Search Results - "Pichler, WJ"

Classification of Drug Hypersensitivity into Allergic, p-i, and Pseudo-Allergic Forms by Pichler, Werner J, Hausmann, Oliver

“…Drug hypersensitivity reactions (DHR) are clinically and functionally heterogeneous. Different subclassifications based on timing of symptom appearance or type…”
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Delayed drug hypersensitivity reactions by PICHLER, Werner J

“…Immune reactions to small molecular compounds, such as drugs, can cause a variety of diseases involving the skin, liver, kidney, and lungs. In many drug…”
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Controversies in drug allergy: In vitro testing by Mayorga, Cristobalina, Ebo, Didier G., Lang, David M., Pichler, Werner J., Sabato, Vito, Park, Miguel A., Makowska, Joanna, Atanaskovic-Markovic, Marina, Bonadonna, Patrizia, Jares, Edgardo

“…Despite their low frequency, drug hypersensitivity reactions (DHRs) can be serious and result in lifelong sequelae. The diagnosis is critical to avert future…”
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Multiple Drug Hypersensitivity by Pichler, Werner J, Srinoulprasert, Yuttana, Yun, James, Hausmann, Oliver

“…Multiple drug hypersensitivity (MDH) is a syndrome that develops as a consequence of massive T-cell stimulations and is characterized by long-lasting drug…”
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The lymphocyte transformation test in the diagnosis of drug hypersensitivity by Pichler, W. J., Tilch, J.

“…Diagnosis of drug hypersensitivity is difficult, as an enormous amount of different drugs can elicit various immune‐mediated diseases with distinct…”
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Pharmacological interaction of drugs with antigen-specific immune receptors: the p-i concept by Pichler, Werner J

“…PURPOSE OF REVIEWDrug allergies are examples of immune reactions to small molecular compounds. In many drug allergies drug specific CD4+ and CD8+ T-cells can…”
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Drug provocation testing in the diagnosis of drug hypersensitivity reactions: general considerations by Aberer, W., Bircher, A., Romano, A., Blanca, M., Campi, P., Fernandez, J., Brockow, K., Pichler, W. J., Demoly, P.

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Diagnosis of nonimmediate reactions to β‐lactam antibiotics by Romano, A., Blanca, M., Torres, M. J., Bircher, A., Aberer, W., Brockow, K., Pichler, W. J., Demoly, P.

“…Nonimmediate manifestations (i.e. occurring more than 1 h after drug administration), particularly maculopapular and urticarial eruptions, are common during…”
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Long-lasting reactivity and high frequency of drug-specific T cells after severe systemic drug hypersensitivity reactions by Beeler, Andreas, Engler, Olivier, Gerber, Basil O., Pichler, Werner J.

“…Drug-reactive T cells are involved in most drug-induced hypersensitivity reactions. The frequency of such cells in peripheral blood of patients with drug…”
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P20: DOES CHLORHEXIDINE SPECIFIC IgE CROSS‐REACT WITH ALEXIDINE? by Pichler, WJ, Buenter, A, Fernando, S, Wirth, N, Helbling, A, Glatz, M, Spoerl, D, Gupta, N, Hausmann, O

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Incidence of anaphylaxis with circulatory symptoms: a study over a 3-year period comprising 940 000 inhabitants of the Swiss Canton Bern by Helbling, A., Hurni, T., Mueller, U. R., Pichler, W. J.

“…Summary Background Diagnosis of anaphylaxis is clinically based and usually straightforward. However, data on the epidemiology of anaphylaxis, particularly the…”
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Levocetirizine is an effective treatment in patients suffering from chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled, parallel, multicenter study by Kapp, Alexander, Pichler, Werner J.

“…Background  Chronic idiopathic urticaria (CIU) is defined by the almost daily presence of urticaria for at least 6 weeks without an identifiable cause…”
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T-cell involvement in drug-induced acute generalized exanthematous pustulosis by Britschgi, M, Steiner, U C, Schmid, S, Depta, J P, Senti, G, Bircher, A, Burkhart, C, Yawalkar, N, Pichler, W J

“…Acute generalized exanthematous pustulosis (AGEP) is an uncommon eruption most often provoked by drugs, by acute infections with enteroviruses, or by mercury…”
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Immune mechanism of drug hypersensitivity by Pichler, Werner J

“…Drug hypersensitivity reactions can lead to a great variety of different diseases. The main cause is a specific interaction of antibodies or T cells with a…”
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Management of hypersensitivity reactions to iodinated contrast media by Brockow, K., Christiansen, C., Kanny, G., Clément, O., Barbaud, A., Bircher, A., DeWachter, P., Guéant, J.‐L., Rodriguez Guéant, R.‐M., Mouton‐Faivre, C., Ring, J., Romano, A., Sainte‐Laudy, J., Demoly, P., Pichler, W. J.

“…All iodinated contrast media (CM) are known to cause both immediate (≤1 h) and nonimmediate (>1 h) hypersensitivity reactions. Although for most immediate…”
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T cell-mediated hypersensitivity to quinolones: mechanisms and cross-reactivity by Schmid, D. A., Depta, J. P.H., Pichler, W. J.

“…Summary Background Quinolones are widely used, broad spectrum antibiotics that can induce immediate‐ and delayed‐type hypersensitivity reactions, presumably…”
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Characterization of Human T Cells That Regulate Neutrophilic Skin Inflammation by Schaerli, Patrick, Britschgi, Markus, Keller, Monika, Steiner, Urs C, Steinmann, Lisa S, Moser, Bernhard, Pichler, Werner J

“…It is unknown whether neutrophilic inflammations can be regulated by T cells. This question was analyzed by studying acute generalized exanthematous pustulosis…”
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Effect of tree pollen specific, subcutaneous immunotherapy on the oral allergy syndrome to apple and hazelnut by Bucher, X., Pichler, W. J., Dahinden, C. A., Helbling, A.

“…Background:  The efficacy of specific immunotherapy (SIT) in pollen allergy is well established. However, its effect on pollen associated food allergy…”
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Drug hypersensitivity: questionnaire by Demoly, P., Kropf, R., Pichler, W.J., Bircher, A.

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T Cell-Regulated Neutrophilic Inflammation in Autoinflammatory Diseases by Keller, Monika, Spanou, Zoi, Schaerli, Patrick, Britschgi, Markus, Yawalkar, Nikhil, Seitz, Michael, Villiger, Peter M, Pichler, Werner J

“…Previous studies of acute generalized exanthematous pustulosis, a peculiar drug hypersensitivity reaction, suggested that CXCL8-producing T cells regulate…”
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