Search Results - "Piché, A"
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The inhibition of Bid expression by Akt leads to resistance to TRAIL-induced apoptosis in ovarian cancer cells
Published in Oncogene (07-10-2010)“…Epithelial ovarian cancer (EOC) cells often show increased activity of the PI3K/Akt pathway. In addition, we have previously shown that EOC ascites induce Akt…”
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Downregulation of cell surface CA125 MUC16 induces epithelial-to-mesenchymal transition and restores EGFR signalling in NIH:OVCAR3 ovarian carcinoma cells
Published in British journal of cancer (15-03-2011)“…Background: Epithelial ovarian cancer (EOC) cells are prone to metastasise throughout the peritoneal cavity. The epithelial-to-mesenchymal transition (EMT) is…”
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Ovarian cancer ascites protects from TRAIL-induced cell death through αvβ5 integrin-mediated focal adhesion kinase and Akt activation
Published in Oncogene (17-06-2010)“…Interactions between ovarian cancer cells and the surrounding tumor microenvironment are not well characterized. We have earlier shown that ovarian cancer…”
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Faster Use and Fewer Failures with Needle-Free Nasal Glucagon Versus Injectable Glucagon in Severe Hypoglycemia Rescue: A Simulation Study
Published in Diabetes technology & therapeutics (01-07-2017)“…During severe hypoglycemic episodes, people with diabetes depend on others to help with treatment. We compared needle-free nasal glucagon and commercially…”
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A phase 3 multicenter, open‐label, prospective study designed to evaluate the effectiveness and ease of use of nasal glucagon in the treatment of moderate and severe hypoglycemia in children and adolescents with type 1 diabetes in the home or school setting
Published in Pediatric diabetes (01-08-2018)“…Objective This multicenter, open‐label study was designed to evaluate real‐world effectiveness and ease of use of nasal glucagon (NG) in treating moderate or…”
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Prospective study evaluating the use of nasal glucagon for the treatment of moderate to severe hypoglycaemia in adults with type 1 diabetes in a real‐world setting
Published in Diabetes, obesity & metabolism (01-05-2018)“…In the present multicentre, open‐label, prospective, phase III study, we evaluated the real‐world effectiveness and ease of use of nasal glucagon (NG) in the…”
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HDL-cholesterol-raising effect of orange juice in subjects with hypercholesterolemia
Published in The American journal of clinical nutrition (01-11-2000)“…Orange juice-a rich source of vitamin C, folate, and flavonoids such as hesperidin-induces hypocholesterolemic responses in animals. We determined whether…”
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PEGylated insulin in PLGA microparticles. In vivo and in vitro analysis
Published in Journal of controlled release (02-06-2005)“…A novel controlled release formulation has been developed with PEGylated human insulin encapsulated in PLGA microspheres that produces multi-day release in…”
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Urodynamic parameters and plasma LH/FSH in spayed Beagle bitches before and 8 weeks after GnRH depot analogue treatment
Published in Theriogenology (01-12-2006)“…The pathophysiology of urinary incontinence due to spaying remains unknown. Incontinent bitches can be treated successfully with depot preparations of…”
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Glucagon Nasal Powder: A Promising Alternative to Intramuscular Glucagon in Youth With Type 1 Diabetes
Published in Diabetes care (01-04-2016)“…Treatment of severe hypoglycemia outside of the hospital setting is limited to intramuscular glucagon requiring reconstitution prior to injection. The current…”
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Intranasal Glucagon for Treatment of Insulin-Induced Hypoglycemia in Adults With Type 1 Diabetes: A Randomized Crossover Noninferiority Study
Published in Diabetes care (01-02-2016)“…Treatment of severe hypoglycemia with loss of consciousness or seizure outside of the hospital setting is presently limited to intramuscular glucagon requiring…”
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Clinical and endocrine responses to treatment with deslorelin acetate implants in ferrets with adrenocortical disease
Published in American journal of veterinary research (01-05-2005)“…To evaluate the clinical and endocrine responses of ferrets with adrenocortical disease (ACD) to treatment with a slow-release implant of deslorelin acetate…”
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Cell detachment modulates TRAIL resistance in ovarian cancer cells by downregulating the phosphatidylinositol 3-kinase/Akt pathway
Published in International journal of gynecological cancer (01-07-2008)“…TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) is a potent inducer of apoptosis but many ovarian cancer cells display intrinsic resistance to…”
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Changes in plasma gonadotropin concentrations and urethral closure pressure in the bitch during the 12 months following ovariectomy
Published in Theriogenology (01-11-2004)“…Urinary incontinence due to acquired urethral sphincter incompetence is a common side effect of spaying, for which the underlying cause remains unknown…”
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FSH and LH plasma levels in bitches with differences in risk for urinary incontinence
Published in Theriogenology (01-05-2005)“…To determine whether the height of the plasma gonadotropin levels after spaying is associated with urinary incontinence, the concentrations of plasma follicle…”
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Multicenter Evaluation of the Clinical Performance and the Neutralizing Antibody Activity Prediction Properties of 10 High-Throughput Serological Assays Used in Clinical Laboratories
Published in Journal of clinical microbiology (18-02-2021)“…As the coronavirus disease 2019 (COVID-19) pandemic second wave is emerging, it is of the upmost importance to screen the population immunity in order to keep…”
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The effect of GnRH analogs on urinary incontinence after ablation of the ovaries in dogs
Published in Theriogenology (15-10-2003)“…After removal of the ovaries approximately 20% of dogs develop urinary incontinence. Removal of the gonads results in estrogen deficiency and chronic elevation…”
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2-hydroxyestradiol is a prodrug of 2-methoxyestradiol
Published in The Journal of pharmacology and experimental therapeutics (01-06-2004)“…Previous in vivo studies indicate that 2-hydroxyestradiol (2OHE) attenuates cardiovascular and renal diseases. In vitro studies suggest that the biological…”
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