Search Results - "Picco, Agustín S."
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Short Zwitterionic Sulfobetaine-Modified Silica Nanoparticles: Is Neutrality Possible?
Published in Langmuir (28-05-2024)“…Zwitterionic coatings are an efficient strategy for preventing biomolecule adsorption and enhancing nanoparticle stability in solution. The properties of…”
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Enhanced Hydrogen Bonding by Urea Functionalization Tunes the Stability and Biological Properties of Peptide Amphiphiles
Published in Biomacromolecules (13-05-2024)“…Self-assembled nanostructures such as those formed by peptide amphiphiles (PAs) are of great interest in biological and pharmacological applications. Herein, a…”
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Control of Peptide Amphiphile Supramolecular Nanostructures by Isosteric Replacements
Published in Biomacromolecules (09-08-2021)“…Supramolecular nanostructures with tunable properties can have applications in medicine, pharmacy, and biotechnology. In this work, we show that the…”
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Urea-Modified Self-Assembling Peptide Amphiphiles That Form Well-Defined Nanostructures and Hydrogels for Biomedical Applications
Published in ACS applied bio materials (17-10-2022)“…Hydrogen bonding plays a critical role in the self-assembly of peptide amphiphiles (PAs). Herein, we studied the effect of replacing the amide linkage between…”
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Mesophase Transformation in Amphiphilic Hyperbranched Polymers Induced by Transition Metal Ion Complexation. Creating Well-Defined Metallo-Supramolecular Assemblies from “Ill-Defined” Building Blocks
Published in ACS macro letters (20-01-2015)“…Self-organized metallo-supramolecular heterostructures have potential applications that include molecular electronics, photovoltaics, and magnetic devices,…”
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Cysteamine-modified ZIF-8 colloidal building blocks: Direct assembly of nanoparticulate MOF films on gold surfaces via thiol chemistry
Published in Materials today chemistry (01-06-2018)“…Chemical modification of metal organic framework (MOF) nanocrystal colloids was used to endow them with chemical affinity for gold substrates. Modified…”
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Synthesis and Structural Characterization of Water-Soluble Gold(I) N‑Heterocyclic Carbene Complexes. An X‑ray Absorption Fine Structure Spectroscopy (XAFS) Study
Published in Organometallics (11-11-2013)“…Water-soluble gold(I) N-heterocyclic carbene complexes were synthesized and characterized using X-ray absorption spectroscopy (XAFS) in combination with…”
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Acetylated galactopyranosyl N-heterocyclic monocarbene complexes of Silver(I) as novel anti-proliferative agents in a rhabdomyosarcoma cell line
Published in Bioorganic & medicinal chemistry (01-06-2024)“…[Display omitted] Herein, four silver(I) complexes bearing acetylated d-galactopyranoside-based N-heterocyclic carbene ligands were synthesized and fully…”
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Supramacromolecular organization of gold nanocrystals capped with amphiphilic hyperbranched polyethyleneimine
Published in Journal of colloid and interface science (01-05-2013)“…[Display omitted] ► The supramolecular hetero-assemblies were studied using synchrotron-based SAXS. ► Nanoscale objects are spontaneously integrated into…”
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Temperature-driven self-assembly of self-limiting uniform supraparticles from non-uniform unimolecular micelles
Published in Journal of colloid and interface science (01-06-2016)“…[Display omitted] In this work, the self-assembly of non-uniform unimolecular micelles constituted of a hyperbranched polyester core decorated with a corona of…”
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Inside the Protein Corona: From Binding Parameters to Unstained Hard and Soft Coronas Visualization
Published in Nano letters (13-10-2021)Get full text
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Distinguishing Protein Corona from Nanoparticle Aggregate Formation in Complex Biological Media Using X‑ray Photon Correlation Spectroscopy
Published in Nano letters (23-10-2024)“…In biological systems, nanoparticles interact with biomolecules, which may undergo protein corona formation that can result in noncontrolled aggregation…”
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Hybrid Nanogel‐Wrapped Anisotropic Gold Nanoparticles Feature Enhanced Photothermal Stability
Published in Small (Weinheim an der Bergstrasse, Germany) (02-09-2024)“…Anisotropic gold nanoparticles (AuNPs) are renowned for their unique properties – including localized surface plasmon resonance (LSPR) and adjustable optical…”
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Protein corona meets freeze-drying: overcoming the challenges of colloidal stability, toxicity, and opsonin adsorption
Published in Nanoscale (14-01-2021)“…Freeze-drying of nanoparticle suspensions is capable of generating stable nanoformulations with improved storage times and easier transportation. Nonetheless,…”
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Freeze-drying of silica nanoparticles: redispersibility toward nanomedicine applications
Published in Nanomedicine (London, England) (01-01-2018)“…To study freeze-drying of silica nanoparticles (SiO NPs) in order to find suitable conditions to produce lyophilized powders with no aggregation after…”
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Control of Peptide Amphiphile Supramolecular Nanostructures by Isosteric Replacements
Published in Biomacromolecules (22-07-2021)“…Supramolecular nanostructures with tunable properties can have applications in medicine, pharmacy, and biotechnology. In this work, we show that the…”
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Understanding protein adsorption on silica mesoporous materials through thermodynamic simulations
Published in Surfaces and interfaces (01-09-2024)“…This work presents a molecular thermodynamic theory to study protein interactions within a charge-regulating silica-like nanopore structure. The theory…”
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Tailored Silica Nanoparticles Surface to Increase Drug Load and Enhance Bactericidal Response
Published in Journal of the Brazilian Chemical Society (01-09-2017)“…Nanoparticles' surface properties can be used as triggers to regulate or even enhance biological response and generate tailored structures to substitute…”
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