Search Results - "Piccini, J P"

QT as a Safety Biomarker in Drug Development by Whellan, DJ, Green, CL, Piccini, JP, Krucoff, MW

“…The cardiovascular safety of new drugs is an overarching concern for all stakeholders: the pharmaceutical industry and the US Food and Drug Administration…”
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Clinical course of atrial fibrillation in older adults: the importance of cardiovascular events beyond stroke by Piccini, Jonathan P, Hammill, Bradley G, Sinner, Moritz F, Hernandez, Adrian F, Walkey, Allan J, Benjamin, Emelia J, Curtis, Lesley H, Heckbert, Susan R

“…Atrial fibrillation increases the risks of stroke, heart failure, and death, and anticoagulation therapy increases the risk of gastrointestinal haemorrhage…”
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Efficacy of adjunctive ablation of complex fractionated atrial electrograms and pulmonary vein isolation for the treatment of atrial fibrillation: a meta-analysis of randomized controlled trials by Kong, Melissa H, Piccini, Jonathan P, Bahnson, Tristram D

“…Although useful, percutaneous left atrial ablation for pulmonary vein isolation (PVI) does not eliminate atrial fibrillation (AF) in all patients. The ablation…”
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Distribution of, and immune response to, chicken anti‐αGal immunoglobulin Y antibodies in wild‐type and αGal knockout mice by Walsh Jr, W. E., Anderson, B. E., Ivancic, D., Zhang, Z., Piccini, J. P., Rodgers, T. G., Pao, W., Fryer, J. P.

“…Summary Chicken antibodies (immunoglobulin Y; IgY) to the αGal epitope (galactose α‐1,3‐galactose) bind to αGal antigens of mouse and porcine tissues and…”
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Rhodopsin maturation antagonized by dominant rhodopsin mutants by Kurada, P, Tonini, T D, Serikaku, M A, Piccini, J P, O'Tousa, J E

“…ninaE(D1), a dominant allele of the major Drosophila rhodopsin gene, expresses a rhodopsin that is predominantly recovered in a 80-kD complex that likely…”
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Higher risk of death and stroke in patients with persistent vs. paroxysmal atrial fibrillation: results from the ROCKET-AF Trial by Steinberg, Benjamin A, Hellkamp, Anne S, Lokhnygina, Yuliya, Patel, Manesh R, Breithardt, Günter, Hankey, Graeme J, Becker, Richard C, Singer, Daniel E, Halperin, Jonathan L, Hacke, Werner, Nessel, Christopher C, Berkowitz, Scott D, Mahaffey, Kenneth W, Fox, Keith A A, Califf, Robert M, Piccini, Jonathan P

“…Anticoagulation prophylaxis for stroke is recommended for at-risk patients with either persistent or paroxysmal atrial fibrillation (AF). We compared outcomes…”
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Prevention of stroke and systemic embolism with rivaroxaban compared with warfarin in patients with non-valvular atrial fibrillation and moderate renal impairment by Fox, Keith A.A., Piccini, Jonathan P., Wojdyla, Daniel, Becker, Richard C., Halperin, Jonathan L., Nessel, Christopher C., Paolini, John F., Hankey, Graeme J., Mahaffey, Kenneth W., Patel, Manesh R., Singer, Daniel E., Califf, Robert M.

“…Aims Patients with non-valvular atrial fibrillation (AF) and renal insufficiency are at increased risk for ischaemic stroke and bleeding during…”
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Dronedarone as early rhythm control: post-hoc analysis of the ATHENA trial using EAST-AFNET4 criteria by Kirchhof, P, Camm, A J, Crijns, H J G M, Piccini, J P, Torp-Pedersen, C, McKindley, D, Stewart, J, Wieloch, M, Hohnloser, S H

“…Abstract Introduction The EAST-AFNET4 study found that early, systematic rhythm control reduced cardiovascular (CV) outcomes in patients with early atrial…”
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Impact of age on patient selection in leadless pacemaker implant: experience with the micra transcatheter pacemaker by Iacopino, S, Roberts, P R, Rao, A, Johansen, J B, Marijon, E, Piccini, J P, El-Chami, M F, Stromberg, K, Fagan, D, Garweg, C

“…Abstract Background The safety and efficacy of the Micra AV leadless pacemaker has been demonstrated in the real-world setting. However, whether the patient…”
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Cost-effectiveness of remote monitoring for cardiac implantable electronic devices compared with conventional follow-up: a systematic review by Arcinas, L A, Alyosif, M, Rennert-May, E, Piccini, J P, Varma, N, Frazier-Mills, C, Raj, S J, Mark, D B, Miller, R J H, Chew, D S

“…Abstract Background Remote monitoring (RM) of cardiovascular implantable electronic devices (CIEDs) is a form of virtual patient care that involves electronic…”
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A leadless ventricular pacemaker providing atrioventricular synchronous pacing in the real-world setting: results from the Micra AV post-approval registry by Garweg, C, Chinitz, J, Marijon, E, Haeberlin, A, Winter, S, Iacopino, S, Curnis, A, Breitenstein, A, Hussin, A, Mela, T, El-Chami, M F, Roberts, P R, Piccini, J P, Stromberg, K, Clementy, N

“…Abstract Introduction Advances in leadless pacemaker technology have enabled accelerometer based atrioventricular synchronous (AVS) pacing by sensing atrial…”
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CO61 Incremental Healthcare Costs for Cardiac Surgery Patients with New-Onset Post-Operative Atrial Fibrillation by Park, TJ, Hansen, R, Gillard, P, Ferguson, W, P Piccini, J, Romano, M, Devine, B

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Incidence and risk factors for major bleeding events in atrial fibrillation patients on direct oral anticoagulant therapy: data from the National Patient-Centered Clinical Research Network by Arps, K, Harrington, J, Carnicelli, A P, Wu, A, Chiswell, K, Chamberlain, A M, Chrischilles, E, Jones, W S, Raj, V, Steinberg, B A, Mundl, H, Viethen, T, Granger, C B, Piccini, J P, Patel, M R

“…Abstract Background Direct oral anticoagulation (DOACs) prevent stroke in patients with atrial fibrillation (AF) and have a superior safety profile compared…”
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Amiodarone for the prevention of sudden cardiac death: a meta-analysis of randomized controlled trials by Piccini, Jonathan P., Berger, Jeffrey S., O’Connor, Christopher M.

“…Aims Not all patients at risk for sudden cardiac death (SCD) are eligible for, or have access to implantable cardioverter defibrillator (ICD) implantation…”
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Management of major bleeding events in patients treated with rivaroxaban vs. warfarin: results from the ROCKET AF trial by Piccini, Jonathan P, Garg, Jyotsna, Patel, Manesh R, Lokhnygina, Yuliya, Goodman, Shaun G, Becker, Richard C, Berkowitz, Scott D, Breithardt, Günter, Hacke, Werner, Halperin, Jonathan L, Hankey, Graeme J, Nessel, Christopher C, Mahaffey, Kenneth W, Singer, Daniel E, Califf, Robert M, Fox, Keith A A

“…There are no data regarding management and outcomes of major bleeding events in patients treated with oral factor Xa inhibitors. Using data from ROCKET AF, we…”
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A leadless ventricular pacemaker providing atrioventricular synchronous pacing in the real-world setting: acute results from the Micra AV post-approval registry by Clementy, N, Chinitz, J, Marijon, E, Haeberlin, A, Winter, S, Iacopino, S, Curnis, A, Breitenstein, A, Hussin, A, Mela, T, El-Chami, M, Roberts, P R, Piccini, J P, Stromberg, K, Garweg, C

“…Abstract Funding Acknowledgements Type of funding sources: Private company. Main funding source(s): Medtronic, inc. Introduction Advances in leadless pacemaker…”
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5970Morbidity and mortality in patients precluded for transvenous pacemaker implantation: experience with the Micra transcatheter pacemaker by Garg, A, Koneru, J N, Fagan, D, Stromberg, K, El-Chami, M F, Piccini, J P, Roberts, P R, Soejima, K, Cheng, A, Ellenbogen, K A

“…Abstract Background The Micra transcatheter pacemaker has proven to be a safe and effective alternative to transvenous pacemakers (TVPs). However, the safety…”
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Efficacy and safety of rivaroxaban compared with warfarin in patients with peripheral artery disease and non-valvular atrial fibrillation: insights from ROCKET AF by Jones, William Schuyler, Hellkamp, Anne S, Halperin, Jonathan, Piccini, Jonathan P, Breithardt, Gunter, Singer, Daniel E, Fox, Keith A A, Hankey, Graeme J, Mahaffey, Kenneth W, Califf, Robert M, Patel, Manesh R

“…Vascular disease is included in a risk scoring system to predict stroke in patients with non-valvular atrial fibrillation (AF). This post hoc analysis of…”
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TT2 CARDIAC PERFORATION AMONG PATIENTS WITH ATRIAL FIBRILLATION UNDERGOING ABLATION: WHAT ARE THE UNDERLYING PREDICTORS? by J Friedman, D., Pokorney, S.D., Ghanem, A., Marcello, S., Kalsekar, I., Yadalam, S., G Akar, J., V Freeman, J., Goldstein, L.J., Khanna, R., P Piccini, J.

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P3783A higher habitual flavonoid intake is associated with a lower risk of atrial fibrillation by Bondonno, N, Murray, K, Bondonno, C P, Lewis, J R, Croft, K D, Kyro, C, Gislason, G, Tjonneland, A, Scalbert, A, Cassidy, A, Piccini, J P, Overvad, K, Dalgaard, F

“…Abstract Background Our understanding of how diet affects future risk of atrial fibrillation (AF) is limited. Evidence suggests that higher habitual intakes of…”
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