Search Results - "Piccaro, Giovanni"

Mycobacterium tuberculosis Is Selectively Killed by Rifampin and Rifapentine in Hypoxia at Neutral pH by Iacobino, Angelo, Piccaro, Giovanni, Giannoni, Federico, Mustazzolu, Alessandro, Fattorini, Lanfranco

“…The activities of rifampin, rifapentine, bedaquiline, PA-824, clofazimine, nitazoxanide, isoniazid, amikacin, moxifloxacin, niclosamide, thioridazine, and…”
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Activities of Drug Combinations against Mycobacterium tuberculosis Grown in Aerobic and Hypoxic Acidic Conditions by PICCARO, Giovanni, GIANNONI, Federico, FILIPPINI, Perla, MUSTAZZOLU, Alessandro, FATTORINI, Lanfranco

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Activity of lipophilic and hydrophilic drugs against dormant and replicating Mycobacterium tuberculosis by Piccaro, Giovanni, Poce, Giovanna, Biava, Mariangela, Giannoni, Federico, Fattorini, Lanfranco

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Mycobacterium tuberculosis gene expression at different stages of hypoxia-induced dormancy and upon resuscitation by Iona, Elisabetta, Pardini, Manuela, Mustazzolu, Alessandro, Piccaro, Giovanni, Nisini, Roberto, Fattorini, Lanfranco, Giannoni, Federico

“…The physiology of dormant Mycobacterium tuberculosis was studied in detail by examining the gene expression of 51 genes using quantitative…”
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Parenteral Vaccination With a Tuberculosis Subunit Vaccine in Presence of Retinoic Acid Provides Early but Transient Protection to M. Tuberculosis Infection by Riccomi, Antonella, Piccaro, Giovanni, Christensen, Dennis, Palma, Carla, Andersen, Peter, Vendetti, Silvia

“…Most microbes invading through mucosal surfaces cause disease and therefore strategies to induce mucosal immune responses are strongly needed. Vitamin A…”
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Moxifloxacin Activates the SOS Response in Mycobacterium tuberculosis in a Dose- and Time-Dependent Manner by Iacobino, Angelo, Piccaro, Giovanni, Pardini, Manuela, Fattorini, Lanfranco, Giannoni, Federico

“…Previous studies on demonstrated that sub-minimum inhibitory concentration (MIC) of fluoroquinolones induced the SOS response, increasing drug tolerance. We…”
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Fighting tuberculosis by drugs targeting nonreplicating Mycobacterium tuberculosis bacilli by Iacobino, Angelo, Piccaro, Giovanni, Giannoni, Federico, Mustazzolu, Alessandro, Fattorini, Lanfranco

“…Current tuberculosis (TB) treatment requires 6 months of combination therapy with isoniazid (INH), rifampin (RIF), pyrazinamide (PZA), and ethambutol for…”
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Targeting dormant bacilli to fight tuberculosis by Fattorini, Lanfranco, Piccaro, Giovanni, Mustazzolu, Alessandro, Giannoni, Federico

“…Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb), which kills about 2 million people annually. Furthermore, 2 billion…”
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Activity of Drug Combinations against Dormant Mycobacterium tuberculosis by FILIPPINI, Perla, IONA, Elisabetta, PICCARO, Giovanni, PEYRON, Pascale, NEYROLLES, Olivier, FATTORINI, Lanfranco

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Caveolin-1 Endows Order in Cholesterol-Rich Detergent Resistant Membranes by Raggi, Carla, Diociaiuti, Marco, Caracciolo, Giulio, Fratini, Federica, Fantozzi, Luca, Piccaro, Giovanni, Fecchi, Katia, Pizzi, Elisabetta, Marano, Giuseppe, Ciaffoni, Fiorella, Bravo, Elena, Fiani, Maria L, Sargiacomo, Massimo

“…Cholesterol-enriched functional portions of plasma membranes, such as caveolae and rafts, were isolated from lungs of wild-type (WT) and caveolin-1 knockout…”
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The M. tuberculosis Phosphate-Binding Lipoproteins PstS1 and PstS3 Induce Th1 and Th17 Responses That Are Not Associated with Protection against M. tuberculosis Infection by Palma, Carla, Spallek, Ralf, Piccaro, Giovanni, Pardini, Manuela, Jonas, Fatima, Oehlmann, Wulf, Singh, Mahavir, Cassone, Antonio

“…The M. tuberculosis phosphate-binding transporter lipoproteins PstS1 and PstS3 were good immunogens inducing CD8+ T-cell activation and both Th1 and Th17…”
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Rifampin induces hydroxyl radical formation in Mycobacterium tuberculosis by Piccaro, Giovanni, Pietraforte, Donatella, Giannoni, Federico, Mustazzolu, Alessandro, Fattorini, Lanfranco

“…The antituberculosis (anti-TB) drug rifampin (RIF) binds to the beta subunit of the RNA polymerase (RpoB) of Mycobacterium tuberculosis, but the bactericidal…”
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The Combination Rifampin-Nitazoxanide, but Not Rifampin-Isoniazid-Pyrazinamide-Ethambutol, Kills Dormant Mycobacterium tuberculosis in Hypoxia at Neutral pH by Iacobino, Angelo, Giannoni, Federico, Pardini, Manuela, Piccaro, Giovanni, Fattorini, Lanfranco

“…The activities of rifampin, nitazoxanide, PA-824, and sutezolid were tested against dormant under conditions mimicking caseous granulomas (hypoxia at pH 7.3)…”
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Gender differences in pain and its relief by Pieretti, Stefano, Di Giannuario, Amalia, Di Giovannandrea, Rita, Marzoli, Francesca, Piccaro, Giovanni, Minosi, Paola, Aloisi, Anna Maria

“…There is much evidence to suggest that gender is an important factor in the modulation of pain. Literature data strongly suggest that men and women differ in…”
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Mycobacterium tuberculosis antigen 85B modifies BCG-induced antituberculosis immunity and favors pathogen survival by Piccaro, Giovanni, Aquino, Gabriella, Gigantino, Vincenzo, Tirelli, Valentina, Sanchez, Massimo, Iorio, Egidio, Matarese, Giuseppe, Cassone, Antonio, Palma, Carla

“…Tuberculosis is one of the deadliest infectious diseases worldwide. Mycobacterium tuberculosis has developed strategies not only to evade host immunity but…”
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Caloric Restriction Promotes Immunometabolic Reprogramming Leading to Protection from Tuberculosis by Palma, Carla, La Rocca, Claudia, Gigantino, Vincenzo, Aquino, Gabriella, Piccaro, Giovanni, Di Silvestre, Dario, Brambilla, Francesca, Rossi, Rossana, Bonacina, Fabrizia, Lepore, Maria Teresa, Audano, Matteo, Mitro, Nico, Botti, Gerardo, Bruzzaniti, Sara, Fusco, Clorinda, Procaccini, Claudio, De Rosa, Veronica, Galgani, Mario, Alviggi, Carlo, Puca, Annibale, Grassi, Fabio, Rezzonico-Jost, Tanja, Norata, Giuseppe Danilo, Mauri, Pierluigi, Netea, Mihai G., de Candia, Paola, Matarese, Giuseppe

“…There is a strong relationship between metabolic state and susceptibility to Mycobacterium tuberculosis (MTB) infection, with energy metabolism setting the…”
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Mycobacterium tuberculosis PstS1 amplifies IFN‐γ and induces IL‐17/IL‐22 responses by unrelated memory CD4+ T cells via dendritic cell activation by Palma, Carla, Schiavoni, Giovanna, Abalsamo, Laura, Mattei, Fabrizio, Piccaro, Giovanni, Sanchez, Massimo, Fernandez, Carmen, Singh, Mahavir, Gabriele, Lucia

“…The immunological mechanisms that modulate protection during Mycobacterium tuberculosis (Mtb) infection or vaccination are not fully understood. Secretion of…”
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Use of probiotics in medical devices applied to some common pathologies by Verrucci, Maria, Iacobino, Angelo, Fattorini, Lanfranco, Marcoaldi, Roberta, Maggio, Antonino, Piccaro, Giovanni

“…Probiotics, defined as "living microorganisms that, whether ingested in useful amount, may have beneficial effects on human body", are widely used in various…”
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Gender-dependent resiliency to stressful and metabolic challenges following prenatal exposure to high-fat diet in the p66(Shc-/-) mouse by Bellisario, Veronica, Berry, Alessandra, Capoccia, Sara, Raggi, Carla, Panetta, Pamela, Branchi, Igor, Piccaro, Giovanni, Giorgio, Marco, Pelicci, Pier G, Cirulli, Francesca

“…Metabolic stressful challenges during susceptible time windows, such as fetal life, can have important implications for health throughout life. Deletion of the…”
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HIV-1 Tat protein vaccination in mice infected with Mycobacterium tuberculosis is safe, immunogenic and reduces bacterial lung pathology by Cafaro, Aurelio, Piccaro, Giovanni, Altavilla, Giuseppe, Gigantino, Vincenzo, Matarese, Giuseppe, Olivieri, Erika, Ferrantelli, Flavia, Ensoli, Barbara, Palma, Carla

“…The therapeutic HIV-1 Tat protein vaccine is in advanced clinical development. Tuberculosis, the main AIDS co-infection, is highly endemic in areas where AIDS…”
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