Time trends of cancer incidence in childhood in Campania region: 25 years of observation

Time trends of cancer incidence in childhood in Campania region: 25 years of observation

Childhood cancer is relatively uncommon and the European age-standardized rate was 164 new case per million per year among children 0 to 14 years of age (95 % CI 158-170). Aims of our study are to evaluate the cases of these malignant diseases observed between 0 and 15 years of age in the Campania r...

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Published in:Italian journal of pediatrics Vol. 42; no. 1; p. 82
Main Authors: Indolfi, Paolo, Picazio, Serena, Perrotta, Silverio, Rossi, Francesca, Pession, Andrea, Di Martino, Martina, Pota, Elvira, Di Pinto, Daniela, Indolfi, Cristiana, Rondelli, Roberto, Vetrano, Francesco, Casale, Fiorina
Format: Journal Article
Language:English
Published: England BioMed Central 06-09-2016
Subjects:
Adolescent
Age
Cancer
Child
Child, Preschool
Disease
Epidemiology
Female
Health risk assessment
Hospitals
Humans
Incidence
Infant
Infant, Newborn
Italy - epidemiology
Leukemia
Lymphoma
Male
Migration
Neoplasms - epidemiology
Nervous system
Oncology
Pediatrics
Population
Risk Factors
Trends
Tumors
Epidemiology
Children
Cancer
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Summary:Childhood cancer is relatively uncommon and the European age-standardized rate was 164 new case per million per year among children 0 to 14 years of age (95 % CI 158-170). Aims of our study are to evaluate the cases of these malignant diseases observed between 0 and 15 years of age in the Campania region between 1990 and 2014, the ration between observed and expected cases by disease and province of residence. Also we studied the percentage of extra-regional migration over the time by disease and province of residence. In this study we reported the patients with malignant disease observed in 25 years (1990-2014) based on the specialized registry, the Mod. 1.01 of the AIEOP (Association Italian Pediatric Hematology-Oncology). The size of the monitored population also allowed us to systematically examine five time trends: 1990-94: 1995-99; 2000-04; 2005-09; and 2010-14. Between 1990 and 2014 a total of 3655 malignant neoplasms were reported: Napoli province (2059 cases), Salerno province (625), Caserta province (589), Avellino province (229), and Benevento province (153). Epidemiological data suggested that about 4100 cases could be expected in Campania region during the same period. The overall ratio between observed (O) and expected (E) numbers of cases in the five periods considered rose gradually from 0.69 in the first period to 0.76, then 0.82, 0.91, and 0.94, in the other periods considered. The extra-regional migration involved 1029 cases (28.1 %), showing a reduction from 33.7 % of the first period to 20.3 % of the last period considered. Considering single province of residence we observed the lowest rate of migration in Napoli and Caserta province, whereas higher levels were observed in the other provinces. For all provinces, except Salerno, the extra-regional migration declined significantly over time. The present findings showed an increase over time of O/E ratio, probably due to improvement in the organization of centers and greater trust of families in local centers. It is possible to further improve the efficiency of healthcare system of Campania region and migration can be reduced with a more rational use of hospitals throughout region.
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ISSN:1824-7288
1720-8424
1824-7288
DOI:10.1186/s13052-016-0287-y