Search Results - "Picarillo, Caryn"
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Dual Inhibition of Interleukin-23 and Interleukin-17 Offers Superior Efficacy in Mouse Models of Autoimmunity
Published in The Journal of pharmacology and experimental therapeutics (01-08-2015)“…Therapies targeting either interleukin (IL)-23 or IL-17 have shown promise in treating T helper 17 (Th17)-driven autoimmune diseases. Although IL-23 is a…”
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Journal Article -
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Immunogenicity Risk Assessment of Process-Related Impurities in An Engineered T Cell Receptor Cellular Product
Published in Journal of pharmaceutical sciences (01-08-2024)“…Cell therapies such as genetically modified T cells have emerged as a promising and viable treatment for hematologic cancers and are being aggressively pursued…”
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Journal Article -
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Discovery and Characterization of a Novel CD4-Binding Adnectin with Potent Anti-HIV Activity
Published in Antimicrobial agents and chemotherapy (01-08-2017)“…A novel fibronectin-based protein (Adnectin) HIV-1 inhibitor was generated using selection. This inhibitor binds to human CD4 with a high affinity (3.9 nM) and…”
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Journal Article