Search Results - "Picarda, Elodie"

Molecular Pathways: Targeting B7-H3 (CD276) for Human Cancer Immunotherapy by Picarda, Elodie, Ohaegbulam, Kim C, Zang, Xingxing

“…B7-H3 (CD276) is an important immune checkpoint member of the B7 and CD28 families. Induced on antigen-presenting cells, B7-H3 plays an important role in the…”
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IL-34 is a Treg-specific cytokine and mediates transplant tolerance by Bézie, Séverine, Picarda, Elodie, Ossart, Jason, Tesson, Laurent, Usal, Claire, Renaudin, Karine, Anegon, Ignacio, Guillonneau, Carole

“…Cytokines and metabolic pathway-controlling enzymes regulate immune responses and have potential as powerful tools to mediate immune tolerance. Blockade of the…”
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Insulin and leptin oscillations license food-entrained browning and metabolic flexibility by Mattar, Pamela, Reginato, Andressa, Lavados, Christian, Das, Debajyoti, Kalyani, Manu, Martinez-Lopez, Nuria, Sharma, Mridul, Skovbjerg, Grethe, Skytte, Jacob Lercke, Roostalu, Urmas, Subbarayan, Rajasekaran, Picarda, Elodie, Zang, Xingxing, Zhang, Jinghang, Guha, Chandan, Schwartz, Gary, Rajbhandari, Prashant, Singh, Rajat

“…Timed feeding drives adipose browning, although the integrative mechanisms for the same remain unclear. Here, we show that twice-a-night (TAN) feeding…”
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Cross-Reactive Donor-Specific CD8+ Tregs Efficiently Prevent Transplant Rejection by Picarda, Elodie, Bézie, Séverine, Usero, Lorena, Ossart, Jason, Besnard, Marine, Halim, Hanim, Echasserieau, Klara, Usal, Claire, Rossjohn, Jamie, Bernardeau, Karine, Gras, Stéphanie, Guillonneau, Carole

“…To reduce the use of non-specific immunosuppressive drugs detrimental to transplant patient health, therapies in development aim to achieve…”
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Fibrinogen-like protein 2/fibroleukin induces long-term allograft survival in a rat model through regulatory B cells by Bézie, Séverine, Picarda, Elodie, Tesson, Laurent, Renaudin, Karine, Durand, Justine, Ménoret, Séverine, Mérieau, Emmanuel, Chiffoleau, Elise, Guillonneau, Carole, Caron, Lise, Anegon, Ignacio

“…We previously described that in a rat model of heart transplantation tolerance was dependent on CD8+CD45RClow Tregs that over-expressed fibrinogen-like protein…”
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924 Novel immune checkpoint interactions in Medulloblastoma and the TME by Martin, Allison M, Moziak, Kirsten, Munoz Perez, Natalia A, Galbo, Phillip M, Picarda, Elodie, Bell, Robert, Eberhart, Charles G, Zheng, Deyou, Zang, Xingxing

“…BackgroundMedulloblastoma, the most common embryonal brain tumor of childhood, has a cold tumor immune microenvironment, harboring low lymphocytic infiltration…”
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Alloantigenic recognition properties of CD8+ regulatory T cells by Picarda, Elodie, Anegon, Ignacio, Guillonneau, Carole

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Tumor Cholesterol Up, T Cells Down by Picarda, Elodie, Ren, Xiaoxin, Zang, Xingxing

“…Highly suppressive tumor microenvironments often result in T cell dysfunction and inability to control tumors, but factors regulating this process remain…”
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MDB-73. INHIBITING THE B7-H3 CHECKPOINT IN MEDULLOBLASTOMA by Moziak, Kirsten, Pensabene, Juliana, Perez, Natalia Muñoz, Yazejian, Rita, Picarda, Elodie, Zhang, Xingxing, Martin, Allison M

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MEDB-76. Evaluating the B7-H3 checkpoint in Medulloblastoma by Moziak, Kirsten, Picarda, Elodie, Perez, Natalia Muñoz, Galbo, Phillip, Zheng, Deyou, Zang, Xingxing, Martin, Allison

“…Abstract BACKGROUND: There is currently no curative therapy for recurrent/refractory MB. Novel approaches to MB include immunotherapy, such as targeting the…”
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MHC-derived allopeptide activates TCR-biased CD8+ Tregs and suppresses organ rejection by Picarda, Elodie, Bézie, Séverine, Venturi, Vanessa, Echasserieau, Klara, Mérieau, Emmanuel, Delhumeau, Aurélie, Renaudin, Karine, Brouard, Sophie, Bernardeau, Karine, Anegon, Ignacio, Guillonneau, Carole

“…In a rat heart allograft model, preventing T cell costimulation with CD40Ig leads to indefinite allograft survival, which is mediated by the induction of…”
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Compensatory Regulatory Networks between CD8 T, B, and Myeloid Cells in Organ Transplantation Tolerance by Bézie, Séverine, Picarda, Elodie, Ossart, Jason, Martinet, Bernard, Anegon, Ignacio, Guillonneau, Carole

“…In transplantation tolerance, numerous regulatory populations have the capacity to inhibit allograft rejection; however, their compensatory capacities have…”
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The immune checkpoint B7-H3 (CD276) regulates adipocyte progenitor metabolism and obesity development by Picarda, Elodie, Galbo, Jr, Phillip M, Zong, Haihong, Rajan, Meenu Rohini, Wallenius, Ville, Zheng, Deyou, Börgeson, Emma, Singh, Rajat, Pessin, Jeffrey, Zang, Xingxing

“…The immune checkpoint B7-H3 (CD276) is a member of the B7 family that has been studied in the tumor microenvironment and immunotherapy, but its potential role…”
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CD8+ regulatory T cells in solid organ transplantation by Guillonneau, Carole, Picarda, Elodie, Anegon, Ignacio

“…Recent advances in phenotypic identification of CD8 T cells with regulatory properties has allowed better definition of this subset of CD8 Tregs (also called…”
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Transient Anti-CD45RC mAb Treatment Induces Specific Transplant Tolerance Through Potentiation of Tregs by Bézie, Séverine, Picarda, Elodie, Boucault, Laetitia, Autrusseau, Elodie, Kilens, Stéphanie, Meistermann, Dimitri, Martinet, Bernard, Daguin, Véronique, Donnart, Audrey, Charpentier, Eric, David, Laurent, Anegon, Ignacio, Guillonneau, Carole

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Transient antibody targeting of CD45RC induces transplant tolerance and potent antigen-specific regulatory T cells by Picarda, Elodie, Bézie, Séverine, Boucault, Laetitia, Autrusseau, Elodie, Kilens, Stéphanie, Meistermann, Dimitri, Martinet, Bernard, Daguin, Véronique, Donnart, Audrey, Charpentier, Eric, David, Laurent, Anegon, Ignacio, Guillonneau, Carole

“…Rat and human CD4 and CD8 Tregs expressing low levels of CD45RC have strong immunoregulatory properties. We describe here that human CD45 isoforms are…”
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T-cell receptor specificity of CD8(+) Tregs in allotransplantation by Picarda, Elodie, Anegon, Ignacio, Guillonneau, Carole

“…Recent studies in the field of CD8(+) Tregs have allowed a better identification and characterization of this subset of regulatory cells. Their key role in the…”
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Key role of allopeptide-specific CD8(+) Tregs in transplantation by Picarda, Élodie, Ossart, Jason, Bézie, Séverine, Guillonneau, Carole

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MHC-derived allopeptide activates TCR-biased [CD8.sup.+] Tregs and suppresses organ rejection by Picarda, Elodie, Bezie, Severine, Venturi, Vanessa, Echasserieau, Klara, Merieau, Emmanuel, Delhumeau, Aurelie, Renaudin, Karine, Brouard, Sophie, Bernardeau, Karine, Anegon, Ignacio, Guillonneau, Carole

“…In a rat heart allograft model, preventing T cell costimulation with CD40Ig leads to indefinite allograft survival, which is mediated by the induction of…”
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MHC-derived allopeptide activates TCR-biased CD8 super( +) Tregs and suppresses organ rejection by Picarda, Elodie, Bezie, Severine, Venturi, Vanessa, Echasserieau, Klara, Merieau, Emmanuel, Delhumeau, Aurelie, Renaudin, Karine, Brouard, Sophie, Bernardeau, Karine, Anegon, Ignacio, Guillonneau, Carole

“…In a rat heart allograft model, preventing T cell costimulation with CD40Ig leads to indefinite allograft survival, which is mediated by the induction of CD8…”
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