Search Results - "Picard, Felix. S. R."

Tc17 biology and function: Novel concepts by Lückel, Christina, Picard, Felix. S. R., Huber, Magdalena

“…Research over the past years has provided increasing understanding about IL‐17‐producing CD8+ T cells termed Tc17 or IL‐17+CD8+ T cells, their distribution and…”
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DYRK1B blockade promotes tumoricidal macrophage activity in pancreatic cancer by Brichkina, Anna, Ems, Miriam, Suezov, Roman, Singh, Rajeev, Lutz, Veronika, Picard, Felix S R, Nist, Andrea, Stiewe, Thorsten, Graumann, Johannes, Daude, Michael, Diederich, Wibke E, Finkernagel, Florian, Chung, Ho-Ryun, Bartsch, Detlef K, Roth, Katrin, Keber, Corinna, Denkert, Carsten, Huber, Magdalena, Gress, Thomas M, Lauth, Matthias

“…Highly malignant pancreatic ductal adenocarcinoma (PDAC) is characterised by an abundant immunosuppressive and fibrotic tumour microenvironment (TME). Future…”
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IL18 Receptor Signaling Regulates Tumor-Reactive CD8+ T-cell Exhaustion via Activation of the IL2/STAT5/mTOR Pathway in a Pancreatic Cancer Model by Lutz, Veronika, Hellmund, Veronique M, Picard, Felix S R, Raifer, Hartmann, Ruckenbrod, Teresa, Klein, Matthias, Bopp, Tobias, Savai, Rajkumar, Duewell, Peter, Keber, Corinna U, Weigert, Andreas, Chung, Ho-Ryun, Buchholz, Malte, Menke, André, Gress, Thomas M, Huber, Magdalena, Bauer, Christian

“…Intratumoral cytotoxic CD8+ T cells (CTL) enter a dysfunctional state characterized by expression of coinhibitory receptors, loss of effector function, and…”
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