Search Results - "Pica, Christina M."

Imaging 26S proteasome activity and inhibition in living mice by Piwnica-Worms, David, Luker, Gary D, Pica, Christina M, Song, Jiling, Luker, Kathryn E

“…The ubiquitin-proteasome pathway is the central mediator of regulated proteolysis in cells, and defects in this pathway are associated with cancer and…”
Get full text

Noninvasive Bioluminescence Imaging of Herpes Simplex Virus Type 1 Infection and Therapy in Living Mice by Luker, Gary D., Bardill, J. Patrick, Prior, Julie L., Pica, Christina M., Piwnica-Worms, David, Leib, David A.

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Noninvasive Imaging of Protein-Protein Interactions in Living Animals by Luker, Gary D., Sharma, Vijay, Pica, Christina M., Dahlheimer, Julie L., Li, Wei, Ochesky, Joseph, Ryan, Christine E., Piwnica-Worms, Helen, Piwnica-Worms, David

“…Protein-protein interactions control transcription, cell division, and cell proliferation as well as mediate signal transduction, oncogenic transformation, and…”
Get full text

Bioluminescence Imaging Reveals Systemic Dissemination of Herpes Simplex Virus Type 1 in the Absence of Interferon Receptors by Luker, Gary D, Prior, Julie L, Song, Jiling, Pica, Christina M, Leib, David A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Effects of Cholesterol and Enantiomeric Cholesterol on P-Glycoprotein Localization and Function in Low-Density Membrane Domains by Luker, Gary D, Pica, Christina M, Kumar, A. Sampath, Covey, Douglas F, Piwnica-Worms, David

“…Multidrug resistance P-glycoprotein (Pgp) has been reported to localize in low-density, cholesterol-enriched membranes. However, effects of low-density…”
Get full text

Characterization of novel histidine-tagged Tat-peptide complexes dual-labeled with (99m)Tc-tricarbonyl and fluorescein for scintigraphy and fluorescence microscopy by Bullok, Kristin E, Dyszlewski, Mary, Prior, Julie L, Pica, Christina M, Sharma, Vijay, Piwnica-Worms, David

“…To enable concurrent whole body scintigraphy and direct imaging of subcellular localization of permeation peptides, dual-labeled Tat-peptides useful for both…”
Get full text

Novel Tat-Peptide Chelates for Direct Transduction of Technetium-99m and Rhenium into Human Cells for Imaging and Radiotherapy by Polyakov, Valery, Sharma, Vijay, Dahlheimer, Julie L, Pica, Christina M, Luker, Gary D, Piwnica-Worms, David

“…Rapid and efficient delivery of radioactive metal complexes to the cell interior would enable novel applications in medical imaging and radiotherapy. Membrane…”
Get full text

Molecular imaging of protein-protein interactions: Controlled expression of p53 and large T-antigen fusion proteins in vivo by LUKER, Gary D, SHARMA, Vijay, PICA, Christina M, PRIOR, Julie L, WEI LI, PIWNICA-WORMS, David

“…Protein-protein interactions control essential steps in signal transduction pathways and other intracellular processes, and assembly of protein complexes…”
Get full text

Overexpression of IRF9 confers resistance to antimicrotubule agents in breast cancer cells by LUKER, Kathryn E, PICA, Christina M, SCHREIBER, Robert D, PIWNICA-WORMS, David

“…IRF9/p48/ISGF3gamma (IRF9) is an IFN regulatory factor that mediates signaling by type I IFNs (IFNalpha and IFNbeta). After single-step selection of breast…”
Get full text

MDR1 P-glycoprotein Reduces Influx of Substrates without Affecting Membrane Potential by Luker, Gary D., Flagg, Thomas P., Sha, Qun, Luker, Kathryn E., Pica, Christina M., Nichols, Colin G., Piwnica-Worms, David

“…MDR1(multidrug resistance) P-glycoprotein (Pgp; ABCB1) decreases intracellular concentrations of structurally diverse drugs. Although Pgp is generally thought…”
Get full text

Characterization of Novel Histidine-Tagged Tat-Peptide Complexes Dual-Labeled with 99mTc-Tricarbonyl and Fluorescein for Scintigraphy and Fluorescence Microscopy by Bullok, Kristin E, Dyszlewski, Mary, Prior, Julie L, Pica, Christina M, Sharma, Vijay, Piwnica-Worms, David

“…To enable concurrent whole body scintigraphy and direct imaging of subcellular localization of permeation peptides, dual-labeled Tat-peptides useful for both…”
Get full text

In vitro and in vivo characterization of a dual-function green fluorescent protein--HSV1-thymidine kinase reporter gene driven by the human elongation factor 1 alpha promoter by Luker, Gary D, Luker, Kathryn E, Sharma, Vijay, Pica, Christina M, Dahlheimer, Julie L, Ocheskey, Joe A, Fahrner, Timothy J, Milbrandt, Jeffrey, Piwnica-Worms, David

“…Toward the goal of monitoring activity of native mammalian promoters with molecular imaging techniques, we stably transfected DU145 prostate carcinoma cells…”
Get full text

Effects of Cholesterol and Enantiomeric Cholesterol on P-Glycoprotein Localization and Function in Low-Density Membrane Domains by Luker, Gary D, Pica, Christina M, Kumar, A. Sampath, Covey, Douglas F, Piwnica-Worms, David

Get full text

Characterization of a novel 99mTc-carbonyl complex as a functional probe of MDR1 P-glycoprotein transport activity by Dyszlewski, Mary, Blake, Helen M, Dahlheimer, Julie L, Pica, Christina M, Piwnica-Worms, David

“…Multidrug resistance (MDR) mediated by overexpression of MDR1 P-glycoprotein (Pgp) is one of the best characterized barriers to chemotherapy in cancer…”
Get full text

In Vitro and In Vivo Characterization of a Dual-Function Green Fluorescent Protein–HSV1-Thymidine Kinase Reporter Gene Driven by the Human Elongation Factor 1α Promoter by Luker, Gary D., Luker, Kathryn E., Sharma, Vijay, Pica, Christina M., Dahlheimer, Julie L., Ocheskey, Joe A., Fahrner, Timothy J., Milbrandt, Jeffrey, Piwnica-Worms, David

“…Toward the goal of monitoring activity of native mammalian promoters with molecular imaging techniques, we stably transfected DU145 prostate carcinoma cells…”
Get full text

Effects of MDR1 and MDR3 P-glycoproteins, MRP1, and BCRP/MXR/ABCP on the transport of (99m)Tc-tetrofosmin by Chen, W S, Luker, K E, Dahlheimer, J L, Pica, C M, Luker, G D, Piwnica-Worms, D

“…Multidrug resistance (MDR1) P-glycoprotein (Pgp), multidrug resistance-associated protein (MRP1), and breast cancer resistance protein (BCRP/MXR/ABCP) are…”
Get full text

Noninvasive imaging of protein-protein interactions in livin animals by Luker, Gary D, Sharma, Vijay, Pica, Christina M, Dahlheimer, Julie L

“…Protein-protein interactions control transcription, cell division, and cell proliferation as well as mediate signal transduction, oncogenic transformation, and…”
Get full text

Characterization of Novel Histidine-Tagged Tat-Peptide Complexes Dual-Labeled with 99m Tc-Tricarbonyl and Fluorescein for Scintigraphy and Fluorescence Microscopy by Bullok, Kristin E., Dyszlewski, Mary, Prior, Julie L., Pica, Christina M., Sharma, Vijay, Piwnica-Worms, David

Get full text

Characterization of a Novel 99m Tc-Carbonyl Complex as a Functional Probe of MDR1 P-Glycoprotein Transport Activity by Dyszlewski, Mary, Blake, Helen M., Dahlheimer, Julie L., Pica, Christina M., Piwnica-Worms, David

“…Multidrug resistance (MDR) mediated by overexpression of MDR1 P-glycoprotein (Pgp) is one of the best characterized barriers to chemotherapy in cancer…”
Get full text

Effects of MDR1 and MDR3 P-glycoproteins, MRP1, and BCRP/MXR/ABCP on the transport of 99mTc-tetrofosmin by Chen, Wendy S., Luker, Kathryn E., Dahlheimer, Julie L., Pica, Christina M., Luker, Gary D., Piwnica-Worms, David

“…Multidrug resistance ( MDR1) P-glycoprotein (Pgp), multidrug resistance-associated protein (MRP1), and breast cancer resistance protein (BCRP/MXR/ABCP) are…”
Get full text