Search Results - "Piazza, P. V."
-
1
Adult hippocampal neurogenesis is involved in anxiety-related behaviors
Published in Molecular psychiatry (01-10-2009)“…Adult hippocampal neurogenesis is a unique example of structural plasticity, the functional role of which has been a matter of intense debate. New transgenic…”
Get full text
Journal Article -
2
Prefrontal synaptic markers of cocaine addiction-like behavior in rats
Published in Molecular psychiatry (01-06-2013)“…Defining the drug-induced neuroadaptations specifically associated with the behavioral manifestation of addiction is a daunting task. To address this issue, we…”
Get full text
Journal Article -
3
Pregnenolone blocks cannabinoid-induced acute psychotic-like states in mice
Published in Molecular psychiatry (01-11-2017)“…Cannabis-induced acute psychotic-like states (CIAPS) represent a growing health issue, but their underlying neurobiological mechanisms are poorly understood…”
Get full text
Journal Article -
4
Simultaneous postprandial deregulation of the orexigenic endocannabinoid anandamide and the anorexigenic peptide YY in obesity
Published in International Journal of Obesity (01-06-2012)“…Background: The endocannabinoid system is a potential pharmacotherapy target for obesity. However, the role of this system in human food intake regulation is…”
Get full text
Journal Article -
5
Differential effects of learning on neurogenesis: learning increases or decreases the number of newly born cells depending on their birth date
Published in Molecular psychiatry (01-12-2003)“…The hippocampal formation, to which new neurons are added on a daily basis throughout life, is important in spatial learning. Surviving de novo produced cells…”
Get full text
Journal Article -
6
Palmitoylethanolamide Stimulation Induces Allopregnanolone Synthesis in C6 Cells and Primary Astrocytes: Involvement of Peroxisome-Proliferator Activated Receptor-α
Published in Journal of neuroendocrinology (01-07-2011)“…Palmitoylethanolamide (PEA) regulates many pathophysiological processes in the central nervous system, including pain perception, convulsions and…”
Get full text
Journal Article -
7
The role of stress in drug self-administration
Published in Trends in pharmacological sciences (Regular ed.) (01-02-1998)“…Environmental experiences have an important effect on the sensitivity of an individual to drugs of abuse. Studies of drug self-administration in laboratory…”
Get full text
Journal Article -
8
Lifelong corticosterone level determines age-related decline in neurogenesis and memory
Published in Neurobiology of aging (01-04-2006)“…Ageing is accompanied by an alteration of spatial memory, a decline in hippocampal neurogenesis and a dysregulation of the hypothalamic–pituitary axis (HPA)…”
Get full text
Journal Article -
9
Motherhood-induced memory improvement persists across lifespan in rats but is abolished by a gestational stress
Published in The European journal of neuroscience (01-06-2006)“…Motherhood modifies the biology and behavior of the female, a process which prepares the mother's cognitive systems that are needed for nurturance. It has…”
Get full text
Journal Article -
10
Pregnenolone sulfate enhances neurogenesis and PSA-NCAM in young and aged hippocampus
Published in Neurobiology of aging (2005)“…Age-dependent cognitive impairments have been correlated with functional and structural modifications in the hippocampal formation. In particular, the brain…”
Get full text
Journal Article -
11
Abolition and Reversal of Strain Differences in Behavioral Responses to Drugs of Abuse after a Brief Experience
Published in Science (American Association for the Advancement of Science) (21-07-2000)“…Inbred strains of mice are largely used to identify the genetic basis of normal and pathological behaviors. This report demonstrates that a moderate period of…”
Get full text
Journal Article -
12
SR141716, a CB1 receptor antagonist, decreases the sensitivity to the reinforcing effects of electrical brain stimulation in rats
Published in Psychopharmacologia (01-09-2001)“…The endogenous cannabinoid system is thought to play a role in reinforcement processes. We tested the effects of five doses of the cannabinoid receptor 1 (CB1)…”
Get full text
Journal Article -
13
PAI-1 protein is a key molecular effector in the transition from normal to PTSD-like fear memory
Published in Molecular psychiatry (01-09-2021)“…Moderate stress increases memory and facilitates adaptation. In contrast, intense stress can induce pathological memories as observed in post-traumatic stress…”
Get full text
Journal Article -
14
Integrated physiology and pathophysiology of CB1-mediated effects of the endocannabinoid system
Published in Diabetes & metabolism (01-04-2007)“…Abstract The discovery of the endocannabinoid system (ECS) has raised a large interest in the scientific community providing us with a strikingly long list of…”
Get full text
Journal Article -
15
Gene expression regulation following behavioral sensitization to cocaine in transgenic mice lacking the glucocorticoid receptor in the brain
Published in Neuroscience (01-01-2006)“…Several findings suggest that glucocorticoid hormones influence the propensity of an individual to develop cocaine abuse. These hormones activate two related…”
Get full text
Journal Article -
16
Study of the addictive potential of modafinil in naive and cocaine-experienced rats
Published in Psychopharmacologia (01-06-2002)“…Modafinil is a drug that promotes wakefulness and, as such, is used to treat hypersomnia and narcolepsy. Preclinical and clinical studies suggest that…”
Get full text
Journal Article -
17
Adoption reverses the long-term impairment in glucocorticoid feedback induced by prenatal stress
Published in The Journal of neuroscience (01-01-1995)“…The development of the organism is subjected to critical and complex influences during the perinatal period. Prenatal and postnatal stresses can have different…”
Get full text
Journal Article -
18
Corticosterone in the Range of Stress-Induced Levels Possesses Reinforcing Properties: Implications for Sensation-Seeking Behaviors
Published in Proceedings of the National Academy of Sciences - PNAS (15-12-1993)“…In both humans and animals certain individuals seek stimuli or situations that are considered stressful and consequently avoided by others. A common feature of…”
Get full text
Journal Article -
19
Glucocorticoids have State-Dependent Stimulant Effects on the Mesencephalic Dopaminergic Transmission
Published in Proceedings of the National Academy of Sciences - PNAS (06-08-1996)“…An increase in the activity of mesencephalic dopaminergic neurons has been implicated in the appearance of pathological behaviors such as psychosis and drug…”
Get full text
Journal Article -
20
Implication of corticosteroid receptors in the regulation of hippocampal structural plasticity
Published in The European journal of neuroscience (01-12-2003)“…The dentate gyrus is one of the few areas of the adult brain that continues to produce neurons and to express the embryonic polysialylated isoforms of neuronal…”
Get full text
Journal Article