Search Results - "Piazuelo, Elena"

Omega-3 Polyunsaturated Fatty Acids and Their Bioactive Metabolites in Gastrointestinal Malignancies Related to Unresolved Inflammation. A Review by Irún, Pilar, Lanas, Angel, Piazuelo, Elena

“…Chronic inflammation takes part in the pathogenesis of some malignancies of the gastrointestinal tract including colorectal (CRC), gastric, and esophageal…”
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Serum lipid mediator profiles in COVID-19 patients and lung disease severity: a pilot study by Irún, Pilar, Gracia, Rafael, Piazuelo, Elena, Pardo, Julián, Morte, Elena, Paño, José Ramon, Boza, Julio, Carrera-Lasfuentes, Patricia, Higuera, Gustavo A., Lanas, Angel

“…Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is highly heterogeneous, ranging from asymptomatic to severe and fatal cases. COVID-19 has…”
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Novel Drug-like HsrA Inhibitors Exhibit Potent Narrow-Spectrum Antimicrobial Activities against Helicobacter pylori by Casado, Javier, Olivan-Muro, Irene, Algarate, Sonia, Chueca, Eduardo, Salillas, Sandra, Velázquez-Campoy, Adrián, Piazuelo, Elena, Fillat, María F, Sancho, Javier, Lanas, Ángel, González, Andrés

“…infection constitutes a silent pandemic of global concern. In the last decades, the alarming increase in multidrug resistance evolved by this pathogen has led…”
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Blood-Cell-Based Inflammatory Markers as a Useful Tool for Early Diagnosis in Colorectal Cancer by Hernandez-Ainsa, Maria, Velamazan, Raul, Lanas, Angel, Carrera-Lasfuentes, Patricia, Piazuelo, Elena

“…BackgroundSystemic inflammation seems to be involved in the pathogenetic pathways of colorectal cancer (CRC). Analytical markers that reflect the inflammatory…”
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Optimizing aspirin dose for colorectal cancer patients through deep phenotyping using novel biomarkers of drug action by Patrignani, Paola, Tacconelli, Stefania, Contursi, Annalisa, Piazuelo, Elena, Bruno, Annalisa, Nobili, Stefania, Mazzei, Matteo, Milillo, Cristina, Hofling, Ulrika, Hijos-Mallada, Gonzalo, Sostres, Carlos, Lanas, Angel

“…Low-dose aspirin's mechanism of action for preventing colorectal cancer (CRC) is still debated, and the optimal dose remains uncertain. We aimed to optimize…”
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Antitumor effects of lactate transport inhibition on esophageal adenocarcinoma cells by Grasa, Laura, Chueca, Eduardo, Arechavaleta, Samantha, García-González, María Asunción, Sáenz, María Ángeles, Valero, Alberto, Hördnler, Carlos, Lanas, Ángel, Piazuelo, Elena

“…As a consequence of altered glucose metabolism, cancer cell intake is increased, producing large amounts of lactate which is pumped out the cytosol by…”
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1,4-Dihydropyridine as a Promising Scaffold for Novel Antimicrobials Against Helicobacter pylori by González, Andrés, Casado, Javier, Gündüz, Miyase Gözde, Santos, Brisa, Velázquez-Campoy, Adrián, Sarasa-Buisan, Cristina, Fillat, María F, Montes, Milagrosa, Piazuelo, Elena, Lanas, Ángel

“…The increasing occurrence of multidrug-resistant strains of the gastric carcinogenic bacterium threatens the efficacy of current eradication therapies. In a…”
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Aspirin and the prevention of colorectal cancer by Ferrández, Ángel, MD, PhD, Piazuelo, Elena, MD, PhD, Castells, Antoni, MD, PhD

“…A large body of evidence from basic science, epidemiologic observations and population-based studies demonstrates that aspirin, as well as other non-steroidal…”
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Proton Pump Inhibitors Display Antitumor Effects in Barrett's Adenocarcinoma Cells by Chueca, Eduardo, Apostolova, Nadezda, Esplugues, Juan V, García-González, María A, Lanas, Ángel, Piazuelo, Elena

“…Recent evidence has reported that proton pump inhibitors (PPIs) can exert antineoplastic effects through the disruption of pH homeostasis by inhibiting…”
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Prevention of cancer in the upper gastrointestinal tract with COX-inhibition. Still an option? by Jiménez, Pilar, García, Asunción, Santander, Sonia, Piazuelo, Elena

“…Epidemiological studies have shown that the regular use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with a reduction of gastrointestinal…”
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Prognostic role of host cyclooxygenase and cytokine genotypes in a Caucasian cohort of patients with gastric adenocarcinoma by García-González, María Asunción, Nicolás-Pérez, David, Lanas, Angel, Bujanda, Luis, Carrera, Patricia, Benito, Rafael, Strunk, Mark, Sopeña, Federico, Santolaria, Santos, Piazuelo, Elena, Jiménez, Pilar, Campo, Rafael, Espinel, Jesús, Manzano, Marisa, Geijo, Fernando, Pellisé, María, González-Huix, Ferrán, Espinós, Jorge, Zaballa, Manuel, Titó, Llúcia, Barranco, Luis, Pazo, Roberto, Quintero, Enrique

“…Genetic factors influencing the prognosis of gastric adenocarcinoma (GAC) are not well known. Given the relevance of cytokines and other pro-inflammatory…”
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Indomethacin but not a selective cyclooxygenase-2 inhibitor inhibits esophageal adenocarcinogenesis in rats by Esquivias, Paula, Morandeira, Antonio, Escartín, Alfredo, Cebrián, Carmelo, Santander, Sonia, Esteva, Francisco, García-González, María Asunción, Ortego, Javier, Lanas, Angel, Piazuelo, Elena

“…AIM： To evaluate the effects of indomethacin [dual cyclooxygenase （COX）-I/COX-2 inhibitor] and 3-（3,4-difluorophenyl）-4-（4-（methylsulfonyl） phenyl）-…”
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Superoxide dismutase prevents development of adenocarcinoma in a rat model of Barrett's esophagus by Piazuelo, Elena, Cebrián, Carmelo, Escartín, Alfredo, Jiménez, Pilar, Soteras, Fernando, Ortego, Javier, Lanas, Angel

“…To test whether antioxidant treatment could prevent the progression of Barrett's esophagus to adenocarcinoma. In a rat model of gastroduodenoesophageal reflux…”
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NSAIDS and gastrointestinal cancer by Piazuelo, Elena, Lanas, Angel

“…A large body of evidence from epidemiological and preclinical studies have shown that nonsteroideal anti-inflammatory drugs (NSAIDs) have a chemopreventive…”
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A case-control study of the association between polymorphisms of the endothelial nitric oxide synthase and glycoprotein IIIa genes and upper gastrointestinal bleeding in users of low-dose aspirin by Piazuelo, Elena, MD, PhD, Fuentes, Javier, MD, PhD, Garcfa-González, María Asunción, MD, PhD, Jiménez, Pilar, MD, PhD, Lanas, Angel, MD, PhD

“…Abstract Background: Previous studies have reported a potential genetic predisposition to NSAID-related upper gastrointestinal (GI) bleeding. Objective: This…”
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Role of gastrin-peptides in Barrett's and colorectal carcinogenesis by Chueca, Eduardo, Lanas, Angel, Piazuelo, Elena

“…Gastrin is the main hormone responsible for the stimulation of gastric acid secretion; in addition, gastrin and its derivatives exert proliferative and…”
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Free radicals and antioxidant systems in reflux esophagitis and Barrett's esophagus by Jiménez, Pilar, Piazuelo, Elena, Sánchez, M Teresa, Ortego, Javier, Soteras, Fernando, Lanas, Angel

“…Experimental studies suggest that free radicals are involved in acid and pepsin-induced damage of esophageal mucosa. The profile and balance between free…”
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Biomarkers of Response to Low-Dose Aspirin in Familial Adenomatous Polyposis Patients by Lanas, Angel, Tacconelli, Stefania, Contursi, Annalisa, Piazuelo, Elena, Bruno, Annalisa, Ronci, Maurizio, Marcone, Simone, Dovizio, Melania, Sopeña, Federico, Falcone, Lorenza, Milillo, Cristina, Mucci, Matteo, Ballerini, Patrizia, Patrignani, Paola

“…The results of Aspirin prevention of colorectal adenomas in patients with familial adenomatous polyposis (FAP) are controversial. We conducted a…”
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Role of gastrin-peptides in Barrett＇s and colorectal carcinogenesis by Eduardo Chueca Angel Lanas Elena Piazuelo

“…Gastrin is the main hormone responsible for the stimu- lation of gastric acid secretion; in addition, gastrin and its derivatives exert proliferative and…”
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Low-Dose Aspirin Affects the Small Bowel Mucosa: Results of a Pilot Study With a Multidimensional Assessment by Smecuol, Edgardo, Pinto Sanchez, Maria Ines, Suarez, Alejandro, Argonz, Julio E, Sugai, Emilia, Vazquez, Horacio, Litwin, Nestor, Piazuelo, Elena, Meddings, Jonathan B, Bai, Julio C, Lanas, Angel

“…Background & Aims Whether low-dose aspirin (acetylsalicylic acid [ASA]) produces intestinal damage is controversial. Our aim was to determine whether the small…”
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