Search Results - "Piascik, M T"

The specific contribution of the novel alpha-1D adrenoceptor to the contraction of vascular smooth muscle by Piascik, M T, Guarino, R D, Smith, M S, Soltis, E E, Saussy, Jr, D L, Perez, D M

“…With a selective antagonist, the specific contribution of the alpha-1D adrenoceptor (AR) to vascular smooth muscle contraction has been assessed. BMY 7378…”
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Solution-phase library screening for the identification of rare clones: isolation of an alpha 1D-adrenergic receptor cDNA by Perez, D M, Piascik, M T, Graham, R M

“…alpha 1-Adrenergic receptor (alpha 1-AR) subtypes (alpha 1A and alpha 1B) play a critical role in vascular smooth muscle contraction and circulatory…”
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The regulation of regional hemodynamics by alpha-1 adrenoceptor subtypes in the conscious rat by Piascik, M T, Smith, M S, Barron, K W, Soltis, E E

“…The role of alpha-1 adrenoceptors sensitive and resistant to chloroethylclonidine (CEC) in the regulation of peripheral hemodynamics in the conscious rat has…”
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Effect of chlorethylclonidine on arterial blood pressure and heart rate in the conscious rat by Piascik, M T, Sparks, M S, Pruitt, T A

“…The effect of chlorethylclonidine (CEC) on arterial blood pressure and heart rate (HR) has been evaluated in the conscious rat. CEC injection (25 mg/kg i.p.)…”
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Agonist interaction with alkylation-sensitive and -resistant alpha-1 adrenoceptor subtypes by Piascik, M T, Butler, B T, Pruitt, T A, Kusiak, J W

“…The interaction of agonists with alpha-1 receptor subtypes sensitive and resistant to alkylation by a prazosin analog…”
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Interaction of imidazolines with alkylation-sensitive and -resistant alpha-1 adrenoceptor subtypes by Piascik, M T, Sparks, M S, Pruitt, T A

“…The interaction of imidazolines with alpha-1 adrenoceptor subtypes sensitive and resistant to inactivation by SZL-49 and chlorethylclonidine (CEC) has been…”
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Interaction of a chemically reactive prazosin analog with alpha-1 adrenoceptors of rat tissues by Kusiak, J W, Pitha, J, Piascik, M T

“…An alkylating analog of prazosin, SZL49 [1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-bicyclo[2.2.2]octa-2,5- diene-2-carbonyl)-piperazine], was synthesized…”
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Effect of an alkylating analog of prazosin on alpha-1 adrenoceptor subtypes and arterial blood pressure by Piascik, M T, Butler, B T, Kusiak, J W, Pitha, J, Holtman, Jr, J R

“…Previous studies have shown that a chemically reactive analog of prazosin, SZL-49, reduces the alpha-1 adrenoceptor population by a maximum of 60% (Kusiak et…”
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Calmodulin stimulation and calcium regulation of smooth muscle adenylate cyclase activity by Piascik, M T, Babich, M, Rush, M E

“…The Ca2+-dependent regulation of the adenylate cyclase activity associated with microsomes isolated from bovine aortic smooth muscle has been studied…”
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Alkylation of alpha-1 receptors with a chemically reactive analog of prazosin reveals low affinity sites for norepinephrine in rabbit aorta by Piascik, M T, Kusiak, J W, Pitha, J, Butler, B T, Le, H T, Babich, M

“…The effect of a newly synthesized irreversible blocker of the alpha-1 receptor [1-(4-amino-6,7-dimethoxy-2-quinazolnyl)-4-(2-bicyclo[2,2,2]…”
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Regulation of the cellular localization and signaling properties of the alpha(1B)- and alpha(1D)-adrenoceptors by agonists and inverse agonists by McCune, D F, Edelmann, S E, Olges, J R, Post, G R, Waldrop, B A, Waugh, D J, Perez, D M, Piascik, M T

“…The regulation of the cellular distribution and intracellular signaling properties of the alpha(1B)- and alpha(1D)- adrenoceptor (alpha(1)-AR) subtypes was…”
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Calmodulin activation and calcium regulation of parotid gland adenylate cyclase by Piascik, M T, Babich, M, Jacobson, K L, Watson, E L

“…The effect of Ca2+ on the adenylate cyclase activity associated with membranes prepared from mouse parotid gland has been examined. Ca2+ stimulated then…”
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Stereoselective and nonstereoselective inhibition exhibited by the enantiomers of verapamil by Piascik, M T, Collins, R, Butler, B T

“…The interaction of the isomers of verapamil with sites on the calcium channel and alpha 1-adrenergic receptor has been examined. The inhibitory potency of…”
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Immunocytochemical localization of the alpha-1B adrenergic receptor and the contribution of this and the other subtypes to vascular smooth muscle contraction: analysis with selective ligands and antisense oligonucleotides by Piascik, M T, Hrometz, S L, Edelmann, S E, Guarino, R D, Hadley, R W, Brown, R D

“…The contribution of the alpha-1B adrenergic receptor (AR) to vascular smooth muscle contraction has been assessed using a combination of immunological,…”
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α-Adrenoceptors and vascular regulation: Molecular, pharmacologic and clinical correlates by Piascik, Michael T., Soltis, Edward E., Piascik, Mary M., Macmillan, Leigh B.

“…This manuscript is intended to provide a comprehensive review of the α-adrenoceptors (ARs) and their role in vascular regulation. The historical development of…”
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The facilitative actions of Bay K 8644 on norepinephrine and KCl-induced contractures of rabbit aortic rings by Piascik, M T, Babich, M

“…The effect of the calcium channel agonist BAY K 8644 on the ability of KCl and norepinephrine to induce contractions of rabbit aortic rings has been examined…”
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Cloning, cell-type specificity, and regulatory function of the mouse alpha(1B)-adrenergic receptor promoter by Zuscik, M J, Piascik, M T, Perez, D M

“…The functionality of a 3422-base pair promoter fragment from the mouse alpha(1B)-adrenergic receptor (alpha(1B)AR) gene was examined. This fragment, cloned…”
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Effect of pentobarbital dependence on adenylate cyclase activity and calmodulin levels in rat cerebral cortex by Piascik, M T, McNicholas, L F

“…The effect of calcium (Ca2+) on the adenylate cyclase activity and calmodulin level of cerebral cortex was determined in pentobarbital dependent rats and age…”
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First degree A-V block in patients on lithium carbonate by Martin, C A, Piascik, M T

“…High doses of lithium in animals and therapeutic doses of lithium in humans caused varied abnormalities in cardiac conduction including A-V block. Five cases…”
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A method for enriching the cadmium content of cigarette smoke and effect of exposure to this smoke on coronary vascular reactivity in the rat by Piascik, M T, Champney, R B, Kasarskis, E J, Forrester, T

“…To study the effect of smoke-borne cadmium on the cardiovascular system, a method was developed to vary the cadmium content in the smoke of Kentucky 2R1…”
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