Search Results - "Piao, Shunfu"

Structural basis for specific recognition of pre-snRNA by Gemin5 by Tang, Xuhua, Bharath, Sakshibeedu R, Piao, Shunfu, Tan, Vanessa Qianmin, Bowler, Matthew W, Song, Haiwei

“…Dear Editor, The survival of motor neurons （SMN） complex assembles the heptameric rings of Sm proteins （Sm core） on small nuclear RNAs （snRNAs） to form small…”
Get full text

Morin attenuates tau hyperphosphorylation by inhibiting GSK3β by Gong, Eun Ji, Park, Hee Ra, Kim, Mi Eun, Piao, Shunfu, Lee, Eunjin, Jo, Dong-Gyu, Chung, Hae Young, Ha, Nam-Chul, Mattson, Mark P, Lee, Jaewon

“…Abstract Alzheimer's disease (AD) is the major form of age-related dementia and is characterized by progressive cognitive impairment, the accumulation of…”
Get full text

Association between polymorphisms rs2228001 and rs2228000 in XPC and genetic susceptibility to preeclampsia: a case control study by Wang, Jingli, Guan, Chengcheng, Sui, Jing, Zang, Yucui, Wu, Yuwen, Zhang, Ru, Qi, Xiaoying, Piao, Shunfu

“…Background Xeroderma pigmentosum complementation group C (XPC) is a DNA damage recognition protein that plays an important role in nucleotide excision repair…”
Get full text

Structural Basis of the PNRC2-Mediated Link between mRNA Surveillance and Decapping by Lai, Tingfeng, Cho, Hana, Liu, Zhou, Bowler, Matthew W., Piao, Shunfu, Parker, Roy, Kim, Yoon Ki, Song, Haiwei

“…Nonsense-mediated mRNA decay (NMD) is an important mRNA surveillance system, and human PNRC2 protein mediates the link between mRNA surveillance and decapping…”
Get full text

Role of Toll-Like Receptor 3 Gene Polymorphisms in Preeclampsia by Chen, Aiping, Li, Congying, Wang, Jingli, Sha, Han, Piao, Shunfu, Liu, Shiguo

“…Background/Aims: Accumulating evidence suggests that an excessive maternal systemic inflammatory response to pregnancy with exaggerated activation of the…”
Get full text

Crystal Structure of the Periplasmic Component of a Tripartite Macrolide-Specific Efflux Pump by Yum, Soohwan, Xu, Yongbin, Piao, Shunfu, Sim, Se-Hoon, Kim, Hong-Man, Jo, Wol-Soon, Kim, Kyung-Jin, Kweon, Hee-Seok, Jeong, Min-Ho, Jeon, Hyesung, Lee, Kangseok, Ha, Nam-Chul

“…In Gram-negative bacteria, type I protein secretion systems and tripartite drug efflux pumps have a periplasmic membrane fusion protein (MFP) as an essential…”
Get full text

Functional Implications of an Intermeshing Cogwheel-like Interaction between TolC and MacA in the Action of Macrolide-specific Efflux Pump MacAB-TolC by Xu, Yongbin, Song, Saemee, Moeller, Arne, Kim, Nahee, Piao, Shunfu, Sim, Se-Hoon, Kang, Mooseok, Yu, Wookyung, Cho, Hyun-Soo, Chang, Iksoo, Lee, Kangseok, Ha, Nam-Chul

“…Macrolide-specific efflux pump MacAB-TolC has been identified in diverse Gram-negative bacteria including Escherichia coli. The inner membrane transporter MacB…”
Get full text

Functional Relationships between the AcrA Hairpin Tip Region and the TolC Aperture Tip Region for the Formation of the Bacterial Tripartite Efflux Pump AcrAB-TolC by KIM, Hong-Man, YONGBIN XU, LEE, Minho, SHUNFU PIAO, SIM, Se-Hoon, HA, Nam-Chul, LEE, Kangseok

“…OA  Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Crystal structure of a clip-domain serine protease and functional roles of the clip domains by Piao, Shunfu, Song, Young-Lan, Kim, Jung Hyun, Park, Sam Yong, Park, Ji Won, Lee, Bok Leul, Oh, Byung-Ha, Ha, Nam-Chul

“…Clip‐domain serine proteases (SPs) are the essential components of extracellular signaling cascades in various biological processes, especially in embryonic…”
Get full text

Structural and Functional Characterization of a Highly Specific Serpin in the Insect Innate Immunity by Park, Sun Hee, Jiang, Rui, Piao, Shunfu, Zhang, Bing, Kim, Eun-Hye, Kwon, Hyun-Mi, Jin, Xiao Ling, Lee, Bok Luel, Ha, Nam-Chul

“…The Toll signaling pathway, an essential innate immune response in invertebrates, is mediated via the serine protease cascade. Once activated, the serine…”
Get full text

CK1ε targets Cdc25A for ubiquitin-mediated proteolysis under normal conditions and in response to checkpoint activation by Piao, Shunfu, Lee, Su-Jin, Xu, Yongbin, Gwak, Jungsug, Oh, Sangtaek, Park, Bum-Joon, Ha, Nam-Chul

“…Cdc25A phosphatase, which is essential in cell cycle progression, is degraded by the proteasome throughout interphase and in response to genotoxic stress…”
Get full text

A Synthetic Peptidoglycan Fragment as a Competitive Inhibitor of the Melanization Cascade by Park, Ji Won, Je, Byung-Rok, Piao, Shunfu, Inamura, Seiichi, Fujimoto, Yukari, Fukase, Koichi, Kusumoto, Shoichi, Söderhäll, Kenneth, Ha, Nam-Chul, Lee, Bok Luel

“…Melanin synthesis is essential for defense and development but must be tightly controlled because systemic hyperactivation of the prophenoloxidase and…”
Get full text

Crystal Structure of the Serine Protease Domain of Prophenoloxidase Activating Factor-I by Piao, Shunfu, Kim, Seulki, Kim, Jung Hyun, Park, Ji Won, Lee, Bok Leul, Ha, Nam-Chul

“…A family of serine proteases (SPs) mediates the proteolytic cascades of embryonic development and immune response in invertebrates. These proteases, called…”
Get full text

Periplasmic Domain of CusA in an Escherichia coli Cu+/Ag+ Transporter Has Metal Binding Sites by Yun, B.Y., Pusan National University, Busan, Republic of Korea, Xu, Yongbin, Pusan National University, Busan, Republic of Korea, Piao, Shunfu, Pusan National University, Busan, Republic of Korea, Kim, N.H., Yonsei University, Seoul, Republic of Korea, Yoon, J.H., Pusan National University, Busan, Republic of Korea, Cho, H.S., Yonsei University, Seoul, Republic of Korea, Lee, K.S., Chung-Ang University, Seoul, Republic of Korea, Ha, N.C., Pusan National University, Busan, Republic of Korea

“…The resistance nodulation division (RND)-type efflux systems are utilized in Gram-negative bacteria to export a variety of substrates. The CusCFBA system is…”
Get full text

Left Atrial Strain and Compliance Correlate with Diastolic Dysfunction Grades and Complications during Pre-eclampsia: A Speckle-Tracking Echocardiography Study by Li, Rui, Sun, Fei, Piao, Shunfu, He, Xiangqin, Li, Rong, Xu, Lin, Song, Guanghui, Cong, Juan

“…This study aimed to investigate left atrium (LA) strain components in the assessment of cardiac function and its clinical correlates in pre-eclampsia (PE)…”
Get full text

Direct Inhibition of GSK3β by the Phosphorylated Cytoplasmic Domain of LRP6 in Wnt/β-Catenin Signaling by Piao, Shunfu, Lee, Sun-Hye, Kim, Hyunjoon, Yum, Soohwan, Stamos, Jennifer L., Xu, Yongbin, Lee, Su-Jin, Lee, Jaewon, Oh, Sangtaek, Han, Jin-Kwan, Park, Bum-Joon, Weis, William I., Ha, Nam-Chul

“…Wnt/β-catenin signaling plays a central role in development and is also involved in a diverse array of diseases. Binding of Wnts to the coreceptors Frizzled…”
Get full text

Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling by Piao, Shunfu, Lee, Sun-Hye, Kim, Hyunjoon, Yum, Soohwan, Stamos, Jennifer L, Xu, Yongbin, Lee, Su-Jin, Lee, Jaewon, Oh, Sangtaek, Han, Jin-Kwan, Park, Bum-Joon, Weis, William I, Ha, Nam-Chul

“…Wnt/beta-catenin signaling plays a central role in development and is also involved in a diverse array of diseases. Binding of Wnts to the coreceptors Frizzled…”
Get full text

Development of Akt-activated GSK3β inhibitory peptide by Kim, Jin-Sik, Piao, Shunfu, Lee, Eunjin, Yoon, Bo-Young, Moon, Hyung Ryong, Lee, Jaewon, Jung, Yunjin, Ha, Nam-Chul

“…•We designed a novel peptide sequence to inhibit GSK3beta.•Activation of the peptide requires the kinase activities of Akt and GSK3beta.•GSK3beta is inhibited…”
Get full text

The tip region of the MacA α-hairpin is important for the binding to TolC to the Escherichia coli MacAB–TolC pump by Xu, Yongbin, Sim, Se-Hoon, Song, Saemee, Piao, Shunfu, Kim, Hong-Man, Jin, Xiao Ling, Lee, Kangseok, Ha, Nam-Chul

“…The tripartite efflux pump MacAB–TolC found in Gram-negative bacteria is involved in resistance to antibiotics. We previously reported the funnel-like…”
Get full text

Crystal structure and thermostability of a putative α-glucosidase from Thermotoga neapolitana by Yun, Bo-Young, Jun, So-Young, Kim, Nam Ah, Yoon, Bo-Young, Piao, Shunfu, Park, So-Hae, Jeong, Seong Hoon, Lee, Heeseob, Ha, Nam-Chul

“…► We determined crystal structure of a putative α-glucosidase from Thermotoga neapolitana. ► We examine the dimeric assembly and Mn 2+ coordination in the…”
Get full text