Analysis of Factors Affecting Short-term Results in Elderly Patients Undergoing Elective Surgical Resection for Stage I-II Colon Cancer

Analysis of Factors Affecting Short-term Results in Elderly Patients Undergoing Elective Surgical Resection for Stage I-II Colon Cancer

The aim of this study was to analyze the influence of comorbidities and to compare the short-term results of elective surgical resection of stage I-II colon adenocarcinoma in elderly (≥65 years) versus younger patients. Two groups of sex-matched younger and older patients were compared: Group A: N=3...

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Bibliographic Details
Published in:Anticancer research Vol. 37; no. 4; pp. 1971 - 1974
Main Authors: Basso, Stefano M M, Lumachi, Franco, Pianon, Patrizio, Fanti, Giovanni, Maffeis, Federica, Ubiali, Paolo
Format: Journal Article
Language:English
Published: Greece 01-04-2017
Subjects:
Adenocarcinoma - pathology
Adenocarcinoma - surgery
Adult
Age Factors
Aged
Aged, 80 and over
Colonic Neoplasms - pathology
Colonic Neoplasms - surgery
Comorbidity
Elective Surgical Procedures
Female
Humans
Male
Middle Aged
Neoplasm Staging
Postoperative Complications
Prognosis
Risk Factors
colorectal cancer
short-term results
comorbidities
complications
Elderly
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Summary:The aim of this study was to analyze the influence of comorbidities and to compare the short-term results of elective surgical resection of stage I-II colon adenocarcinoma in elderly (≥65 years) versus younger patients. Two groups of sex-matched younger and older patients were compared: Group A: N=36, median age 58 (range=43-65) years; and group B: N=67, median age 73 (range=66-86) years. Overall, 71 out of 103 (68.9%) patients had one or more comorbidities. A greater number of older patients had an American Society of Anesthesiologists (ASA) score >2 (p=0.004) and were on multiple medications (polypharmacy) (p=0.016), but the distribution of the other parameters was similar (p≥0.05). Intra- and postoperative complications in group A vs. B occurred in 25.0% vs. 26.9%, and 47.2% vs. 64.2%, respectively (p≥0.05). Elderly patients with colon cancer scheduled to elective surgical resection should not be considered at increased risk of intra- or short-term postoperative complications with respect to younger patients. However, they require careful individual preoperative evaluation because they are usually polypharmacy users and have a higher ASA score.
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ISSN:0250-7005
1791-7530
DOI:10.21873/anticanres.11538