Search Results - "Pi‐Denis, Natalia"
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A novel mutation in the OAR domain of the ARX gene
Published in Clinical case reports (01-02-2017)“…Key Clinical Message Mutations in ARX gene should be considered in patients with mental disability or/and epilepsy. It is an X‐linked gene that has pleiotropic…”
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Dissecting the active site of the collagenolytic cathepsin L3 protease of the invasive stage of Fasciola hepatica
Published in PLoS neglected tropical diseases (2013)“…A family of secreted cathepsin L proteases with differential activities is essential for host colonization and survival in the parasitic flatworm Fasciola…”
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Substrate Specificity of Cysteine Proteases Beyond the S2 Pocket: Mutagenesis and Molecular Dynamics Investigation of Fasciola hepatica Cathepsins L
Published in Frontiers in molecular biosciences (19-04-2018)“…Cysteine proteases are widespread in all life kingdoms, being central to diverse physiological processes based on a broad range of substrate specificity…”
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The major cathepsin L secreted by the invasive juvenile Fasciola hepatica prefers proline in the S2 subsite and can cleave collagen
Published in Molecular and biochemical parasitology (01-09-2009)“…Secreted cysteine proteases are major players in host–parasite interactions; in Fasciola hepatica, a distinct group of cathepsins L was found to be…”
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Substrate Specificity of Cysteine Proteases Beyond the S 2 Pocket: Mutagenesis and Molecular Dynamics Investigation of Fasciola hepatica Cathepsins L
Published in Frontiers in molecular biosciences (19-04-2018)“…Cysteine proteases are widespread in all life kingdoms, being central to diverse physiological processes based on a broad range of substrate specificity…”
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Dissecting the Active Site of the Collagenolytic Cathepsin L3 Protease of the Invasive Stage of Fasciola hepatica: e2269
Published in PLoS neglected tropical diseases (01-07-2013)“…Background A family of secreted cathepsin L proteases with differential activities is essential for host colonization and survival in the parasitic flatworm…”
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A novel mutation in the OAR domain of the ARX gene
Published in Clinical case reports (01-02-2017)Get full text
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