Search Results - "Pi, Haiwei"

Piwi reduction in the aged niche eliminates germline stem cells via Toll-GSK3 signaling by Lin, Kun-Yang, Wang, Wen-Der, Lin, Chi-Hung, Rastegari, Elham, Su, Yu-Han, Chang, Yu-Tzu, Liao, Yung-Feng, Chang, Yi-Chieh, Pi, Haiwei, Yu, Bo-Yi, Chen, Shu-Hwa, Lin, Chung-Yen, Lu, Mei-Yeh, Su, Tsu-Yi, Tzou, Fei-Yang, Chan, Chih-Chiang, Hsu, Hwei-Jan

“…Transposons are known to participate in tissue aging, but their effects on aged stem cells remain unclear. Here, we report that in the Drosophila ovarian…”
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Upregulated TNF/Eiger signaling mediates stem cell recovery and tissue homeostasis during nutrient resupply in Drosophila testis by Chang, Yi Chieh, Tu, Hsin, Huang, To-Wei, Xu, Bo-Wen, Pi, Haiwei

“…Stem cell activity and cell differentiation is robustly influenced by the nutrient availability in the gonads. The signal that connects nutrient availability…”
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Reproduction disrupts stem cell homeostasis in testes of aged male Drosophila via an induced microenvironment by Chang, Yi Chieh, Tu, Hsin, Chen, Jing-Yi, Chang, Ching-Chin, Yang, Shu Yuan, Pi, Haiwei

“…Stem cells rely on instructive cues from their environment. Alterations in microenvironments might contribute to tissue dysfunction and disease pathogenesis…”
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Control of a Novel Spermatocyte-Promoting Factor by the Male Germline Sex Determination Factor PHF7 of Drosophila melanogaster by Yang, Shu Yuan, Chang, Yi-Chieh, Wan, Yu Hsin, Whitworth, Cale, Baxter, Ellen M, Primus, Shekerah, Pi, Haiwei, Van Doren, Mark

“…A key aspect of germ cell development is to establish germline sexual identity and initiate a sex-specific developmental program to promote spermatogenesis or…”
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USP5/Leon deubiquitinase confines postsynaptic growth by maintaining ubiquitin homeostasis through Ubiquilin by Wang, Chien-Hsiang, Huang, Yi-Chun, Chen, Pei-Yi, Cheng, Ying-Ju, Kao, Hsiu-Hua, Pi, Haiwei, Chien, Cheng-Ting

“…Synapse formation and growth are tightly controlled processes. How synaptic growth is terminated after reaching proper size remains unclear. Here, we show that…”
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DDX3 is critical for female fertility via translational control in oogenesis by Tsai, Shang-Yu, Lin, Chih-Hung, Jiang, Yu-Ting, Huang, Guo-Jen, Pi, Haiwei, Hung, Hsin-Yuan, Tarn, Woan-Yuh, Lai, Ming-Chih

“…DEAD-box RNA helicase 3 (DDX3) and its homologs play a vital role in translation initiation by unwinding secondary structures of selected mRNAs. The human DDX3…”
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Aging and insulin signaling differentially control normal and tumorous germline stem cells by Kao, Shih‐Han, Tseng, Chen‐Yuan, Wan, Chih‐Ling, Su, Yu‐Han, Hsieh, Chang‐Che, Pi, Haiwei, Hsu, Hwei‐Jan

“…Summary Aging influences stem cells, but the processes involved remain unclear. Insulin signaling, which controls cellular nutrient sensing and organismal…”
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The COP9 signalosome converts temporal hormone signaling to spatial restriction on neural competence by Huang, Yi-Chun, Lu, Yu-Nung, Wu, June-Tai, Chien, Cheng-Ting, Pi, Haiwei

“…During development, neural competence is conferred and maintained by integrating spatial and temporal regulations. The Drosophila sensory bristles that detect…”
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Nak Regulates Localization of Clathrin Sites in Higher-Order Dendrites to Promote Local Dendrite Growth by Yang, Wei-Kang, Peng, Yu-Huei, Li, Hsun, Lin, Hsiu-Chen, Lin, Yu-Ching, Lai, Tzu-Ting, Suo, Hsien, Wang, Chien-Hsiang, Lin, Wei-Hsiang, Ou, Chan-Yen, Zhou, Xin, Pi, Haiwei, Chang, Henry C., Chien, Cheng-Ting

“…During development, dendrites arborize in a field several hundred folds of their soma size, a process regulated by intrinsic transcription program and…”
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Negative-feedback regulation of proneural proteins controls the timing of neural precursor division by Chang, Pao-Ju, Hsiao, Yun-Ling, Tien, An-Chi, Li, Yi-Chen, Pi, Haiwei

“…Neurogenesis requires precise control of cell specification and division. In Drosophila , the timing of cell division of the sensory organ precursor (SOP) is…”
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Identification of 11-amino acid peptides that disrupt Notch-mediated processes in Drosophila by Pi, Haiwei, Huang, Yi-Chun, Chen, I-Chun, Lin, Chung-De, Yeh, Hsiao-Fong, Pai, Li-Mei

“…The conserved Notch signaling pathway regulates cell fate decisions and maintains stem cells in multicellular organisms. Up-regulation of Notch signaling is…”
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phyllopod Is a Target Gene of Proneural Proteins in Drosophila External Sensory Organ Development by Pi, Haiwei, Huang, Shao-Kuei, Tang, Chiou-Yang, Sun, Y. Henry, Chien, Cheng-Ting, Levine, Michael S.

“…Proneural basic helix-loop-helix (bHLH) proteins initiate neurogenesis in both vertebrates and invertebrates. The Drosophila Achaete (Ac) and Scute (Sc)…”
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A dual function of phyllopod in Drosophila external sensory organ development: cell fate specification of sensory organ precursor and its progeny by Pi, H, Wu, H J, Chien, C T

“…During Drosophila external sensory organ development, one sensory organ precursor (SOP) arises from a proneural cluster, and undergoes asymmetrical cell…”
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Actin-related protein 6 facilitates proneural protein-induced gene activation for rapid neural differentiation by Hsiao, Yun-Ling, Chen, Hui-Wen, Chen, Kuan-Han, Tan, Bertrand Chin-Ming, Chen, Chia-Hsiang, Pi, Haiwei

“…Neurogenesis is initiated by basic helix-loop-helix proneural proteins. Here, we show that Actin-related protein 6 (Arp6), a core component of the H2A.Z…”
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Fringe-positive Golgi outposts unite temporal Furin 2 convertase activity and spatial Delta signal to promote dendritic branch retraction by Li, Hsun, Sung, Hsin-Ho, Huang, Yi-Chun, Cheng, Ying-Ju, Yeh, Hsiao-Fong, Pi, Haiwei, Giniger, Edward, Chien, Cheng-Ting

“…Golgi outposts (GOPs) in dendrites are known for their role in promoting branch extension, but whether GOPs have other functions is unclear. We found that…”
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Smurf-mediated differential proteolysis generates dynamic BMP signaling in germline stem cells during Drosophila testis development by Chang, Yi-Jie, Pi, Haiwei, Hsieh, Chang-Che, Fuller, Margaret T.

“…Germline stem cells (GSCs) produce gametes throughout the reproductive life of many animals, and intensive studies have revealed critical roles of BMP…”
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The COP9 Signalosome Converts Temporal Hormone Signaling to Spatial Restriction on Neural Competence: e1004760 by Huang, Yi-Chun, Lu, Yu-Nung, Wu, June-Tai, Chien, Cheng-Ting, Pi, Haiwei

“…During development, neural competence is conferred and maintained by integrating spatial and temporal regulations. The Drosophila sensory bristles that detect…”
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Proneural proteins Achaete and Scute associate with nuclear actin to promote formation of external sensory organs by Hsiao, Yun-Ling, Chen, Yu-Ju, Chang, Yi-Jie, Yeh, Hsiao-Fong, Huang, Yi-Chun, Pi, Haiwei

“…Basic helix-loop-helix (bHLH) proneural proteins promote neurogenesis through transcriptional regulation. Although much is known about the tissue-specific…”
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Proneural proteins Achaete and Scute associate with nuclear actin to promote external sensory organ formation by Hsiao, Yun-Ling, Chen, Yu-Ju, Chang, Yi-Jie, Yeh, Hsiao-Fong, Huang, Yi-Chun, Pi, Haiwei

“…Basic helix-loop-helix (bHLH) proneural proteins promote neurogenesis through transcriptional regulation. Although much is known about the tissue-specific…”
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CSN-mediated deneddylation differentially modulates Ci155 proteolysis to promote Hedgehog signalling responses by Wu, June-Tai, Lin, Wei-Hsiang, Chen, Wei-Yu, Huang, Yi-Chun, Tang, Chiou-Yang, Ho, Margaret S., Pi, Haiwei, Chien, Cheng-Ting

“…The Hedgehog (Hh) morphogen directs distinct cell responses according to its distinct signalling levels. Hh signalling stabilizes transcription factor cubitus…”
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