Search Results - "Pi, Fengmei"

Nanoparticle orientation to control RNA loading and ligand display on extracellular vesicles for cancer regression by Pi, Fengmei, Binzel, Daniel W., Lee, Tae Jin, Li, Zhefeng, Sun, Meiyan, Rychahou, Piotr, Li, Hui, Haque, Farzin, Wang, Shaoying, Croce, Carlo M., Guo, Bin, Evers, B. Mark, Guo, Peixuan

“…Nanotechnology offers many benefits, and here we report an advantage of applying RNA nanotechnology for directional control. The orientation of arrow-shaped…”
Get full text

Tuning the size, shape and structure of RNA nanoparticles for favorable cancer targeting and immunostimulation by Guo, Sijin, Xu, Congcong, Yin, Hongran, Hill, Jordan, Pi, Fengmei, Guo, Peixuan

“…The past decade has shown exponential growth in the field of RNA nanotechnology. The rapid advances of using RNA nanoparticles for biomedical applications,…”
Get full text

RNA as a stable polymer to build controllable and defined nanostructures for material and biomedical applications by Li, Hui, Lee, Taek, Dziubla, Thomas, Pi, Fengmei, Guo, Sijin, Xu, Jing, Li, Chan, Haque, Farzin, Liang, Xing-Jie, Guo, Peixuan

“…•We reviewed the physicochemical properties of polymers that can apply to RNA.•We reviewed the unique properties of RNA as a polymer.•We reviewed the current…”
Get full text

RNA versatility, flexibility, and thermostability for practice in RNA nanotechnology and biomedical applications by Haque, Farzin, Pi, Fengmei, Zhao, Zhengyi, Gu, Shanqing, Hu, Haibo, Yu, Hang, Guo, Peixuan

“…In recent years, RNA has attracted widespread attention as a unique biomaterial with distinct biophysical properties for designing sophisticated architectures…”
Get full text

Controllable self-assembly of RNA dendrimers by Sharma, Ashwani, PhD, Haque, Farzin, PhD, Pi, Fengmei, MSc, Shlyakhtenko, Lyudmila S., PhD, Guo, Peixuan, PhD

“…Abstract We report programmable self-assembly of branched, 3D globular, monodisperse and nanoscale sized dendrimers using RNA as building blocks. The central…”
Get full text

Design Strategy of Elastoplastic Dampers for Seismic Protection of Structures by Pi, Fengmei, Ren, Wenjie, Chen, Bowen

“…A new methodology for seismic control design of MDOF structures is put forward.The methodology is developed for shear-type building frames with supplemental…”
Get full text

New approach to develop ultra-high inhibitory drug using the power function of the stoichiometry of the targeted nanomachine or biocomplex by Shu, Dan, Pi, Fengmei, Wang, Chi, Zhang, Peng, Guo, Peixuan

“…To find methods for potent drug development by targeting to biocomplex with high copy number. Phi29 DNA packaging motor components with different…”
Get full text

Binomial distribution for quantification of protein subunits in biological Nanoassemblies and functional nanomachines by Fang, Huaming, PhD, Zhang, Peng, PhD, Huang, Lisa P., PhD, Zhao, Zhengyi, BS, Pi, Fengmei, MS, Montemagno, Carlo, PhD, Guo, Peixuan, PhD

“…Abstract Living systems produce ordered structures and nanomachines that inspire the development of biomimetic nanodevices such as chips, MEMS, actuators,…”
Get full text

Controllable Self-Assembly of RNA Tetrahedrons with Precise Shape and Size for Cancer Targeting by Li, Hui, Zhang, Kaiming, Pi, Fengmei, Guo, Sijin, Shlyakhtenko, Luda, Chiu, Wah, Shu, Dan, Guo, Peixuan

“…RNA tetrahedral nanoparticles with two different sizes are successfully assembled by a one‐pot bottom‐up approach with high efficiency and thermal stability…”
Get full text

Stable RNA nanoparticles as potential new generation drugs for cancer therapy by Shu, Yi, Pi, Fengmei, Sharma, Ashwani, Rajabi, Mehdi, Haque, Farzin, Shu, Dan, Leggas, Markos, Evers, B. Mark, Guo, Peixuan

“…Human genome sequencing revealed that only ~1.5% of the DNA sequence coded for proteins. More and more evidence has uncovered that a substantial part of the…”
Get full text

Effective delivery of miR-511-3p with mannose-decorated exosomes with RNA nanoparticles confers protection against asthma by Tu, Wei, Hu, Xinyue, Wan, Rongjun, Xiao, Xiaojun, Shen, Yingchun, Srikaram, Prakhyath, Avvaru, Sai Nithin, Yang, Fuhan, Pi, Fengmei, Zhou, Yufeng, Wan, Mei, Gao, Peisong

“…Our previous studies have shown that miR-511-3p treatment has a beneficial effect in alleviating allergic airway inflammation. Here, we sought to explore its…”
Get full text

RNA Nanoparticles Harboring Annexin A2 Aptamer Can Target Ovarian Cancer for Tumor-Specific Doxorubicin Delivery by Pi, Fengmei, Zhang, Hui, Li, Hui, Thiviyanathan, Varatharasa, Gorenstein, David G, Sood, Anil K, Guo, Peixuan

“…Abstract A novel modified nucleic acid nanoparticle harboring an annexin A2 aptamer for ovarian cancer cell targeting and a GC rich sequence for doxorubicin…”
Get full text

Construction of RNA–Quantum Dot Chimera for Nanoscale Resistive Biomemory Application by Lee, Taek, Yagati, Ajay Kumar, Pi, Fengmei, Sharma, Ashwani, Choi, Jeong-Woo, Guo, Peixuan

“…RNA nanotechnology offers advantages to construct thermally and chemically stable nanoparticles with well-defined shape and structure. Here we report the…”
Get full text

A Simplified Method to Calculate the Additional Interstory Drift of High-Rise Steel Frame Based on the P-Δ Effect by Pi, Fengmei, Ren, Wenjie, Yang, Xinlei, Liu, Gaotong

“…Pi, F.; Ren, W.; Yang, X., and Liu, G., 2020. A simplified method to calculate the additional interstory drift of high-rise steel frame based on the P-Δ…”
Get full text

Abstract NT-112: APTAMER CONJUGATED NANOPARTICLES FOR TARGETED DRUG DELIVERY by Thiviyanathan, Varatharasa, Pi, Fengmei, Zhang, Hui, Li, Hui, Wang, Hongyu, Guo, Peixuan, Sood, Anil

“…Abstract Targeted Delivery of therapeutic drugs and imaging agents, using nanoparticles, shows great promise in diverse fields, including the diagnostics and…”
Get full text

Development of Potent Antiviral Drugs Inspired by Viral Hexameric DNA-Packaging Motors with Revolving Mechanism by Pi, Fengmei, Zhao, Zhengyi, Chelikani, Venkata, Yoder, Kristine, Kvaratskhelia, Mamuka, Guo, Peixuan

“…The intracellular parasitic nature of viruses and the emergence of antiviral drug resistance necessitate the development of new potent antiviral drugs…”
Get full text

Discovery of a new method for potent drug development using power function of stoichiometry of homomeric biocomplexes or biological nanomotors by Pi, Fengmei, Vieweger, Mario, Zhao, Zhengyi, Wang, Shaoying, Guo, Peixuan

“…Multidrug resistance and the appearance of incurable diseases inspire the quest for potent therapeutics. We review a new methodology in designing potent drugs…”
Get more information

In Vitro and In Vivo Evaluation of the Pathology and Safety Aspects of Three- and Four-Way Junction RNA Nanoparticles by Jin, Kai, Liao, You-Cheng, Cheng, Tzu-Chun, Li, Xin, Lee, Wen-Jui, Pi, Fengmei, Jasinski, Daniel, Chen, Li-Ching, Phelps, Mitch A., Ho, Yuan-Soon, Guo, Peixuan

“…RNA therapeutics has advanced into the third milestone in pharmaceutical drug development, following chemical and protein therapeutics. RNA itself can serve as…”
Get full text

Abstract NTOC-109: MULTI–FUNCTIONAL RNA NANOPARTICLES FOR TARGETED DELIVERY OF THERAPEUTIC DRUGS FOR OVARIAN CANCER by Thiviyanathan, Varatharasa, Li, Xin, Pi, Fengmei, Zhang, Hui, Wang, Hongyu, Haque, Farzin, Gorenstein, David, Guo, Peixuan

“…Abstract Targeted delivery of therapeutic drugs and imaging agents remains a promising option in the treatment and diagnosis of ovarian cancer. We have…”
Get full text

Abstract 3147: A novel next generation sequencing strategy for detecting microsatellite instability in colorectal and gastric cancer by Li, Wenyun, Pi, Fengmei, Liang, Xiaoxia, Cao, Taiyuan, Lin, Yiheng, Zhai, Xiaohui, Huang, Mengli, Qin, Hao, Gao, Chan, Cai, Shangli, Wu, Xianrui, Xiao, Jian, Lan, Ping

“…Abstract Background: Microsatellite instability (MSI) has become a critical predictive and prognostic biomarker in multiple cancers. The mainstream…”
Get full text