Search Results - "Phytomedicine (Stuttgart)"

Ginkgetin derived from Ginkgo biloba leaves enhances the therapeutic effect of cisplatin via ferroptosis-mediated disruption of the Nrf2/HO-1 axis in EGFR wild-type non-small-cell lung cancer by Lou, Jian-Shu, Zhao, Li-Ping, Huang, Zhi-Hui, Chen, Xia-Yin, Xu, Jing-Ting, TAI, William Chi-Shing, Tsim, Karl W.K., Chen, Yi-Tao, Xie, Tian

“…Cisplatin (DDP) is the first-in-class drug for advanced and non-targetable non-small-cell lung cancer (NSCLC). A recent study indicated that DDP could slightly…”
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Luteolin protects against diabetic cardiomyopathy by inhibiting NF-κB-mediated inflammation and activating the Nrf2-mediated antioxidant responses by Li, Li, Luo, Wu, Qian, Yuanyuan, Zhu, Weiwei, Qian, Jianchang, Li, Jieli, Jin, Yiyi, Xu, Xuzhong, Liang, Guang

“…Diabetes mellitus is a well-known risk factor for the development of heart failure. Inflammation and oxidative stress play a key role in the development of…”
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Protection against chemotherapy- and radiotherapy-induced side effects: A review based on the mechanisms and therapeutic opportunities of phytochemicals by Liu, Yong-Qiang, Wang, Xiao-Lu, He, Dan-Hua, Cheng, Yong-Xian

“…Although great achievements have been made in the field of cancer therapy, chemotherapy and radiotherapy remain the mainstay cancer therapeutic modalities…”
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Cyclocarya paliurus polysaccharides alleviate type 2 diabetic symptoms by modulating gut microbiota and short-chain fatty acids by Yao, Ye, Yan, Lijing, Chen, Han, Wu, Ning, Wang, Wenbo, Wang, Dongsheng

“…Cyclocarya paliurus polysaccharide (CCPP), a primary active component in the leaves of Cyclocarya paliurus (Batal.) Iljinsk (C. paliurus), has the ability to…”
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A review on pharmacological activities and synergistic effect of quercetin with small molecule agents by Zou, Haoyang, Ye, Haiqing, Kamaraj, Rajamanikkam, Zhang, Tiehua, Zhang, Jie, Pavek, Petr

“…Quercetin is a natural flavonoid, which widely exists in nature, such as tea, coffee, apples, and onions. Numerous studies have showed that quercetin has…”
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Honokiol: A review of its pharmacological potential and therapeutic insights by Rauf, Abdur, Olatunde, Ahmed, Imran, Muhammad, Alhumaydhi, Fahad A., Aljohani, Abdullah S.M., Khan, Shahid Ali, Uddin, Md. Sahab, Mitra, Saikat, Emran, Talha Bin, Khayrullin, Mars, Rebezov, Maksim, Kamal, Mohammad Amjad, Shariati, Mohammad Ali

“…Honokiol is a pleiotropic compound which been isolated from Magnolia species such as Magnolia grandiflora and Magnolia dealbata. Magnolia species Magnolia…”
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Antidiabetic potential of gallic acid from Emblica officinalis: Improved glucose transporters and insulin sensitivity through PPAR-γ and Akt signaling by Variya, Bhavesh C., Bakrania, Anita K., Patel, Snehal S.

“…Nature has gifted a variety of vital phytochemicals having potential therapeutic application against various ailments. Emblica officinalis (E. officinalis), an…”
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β-Caryophyllene suppresses ferroptosis induced by cerebral ischemia reperfusion via activation of the NRF2/HO-1 signaling pathway in MCAO/R rats by Hu, Qingwen, Zuo, Tianrui, Deng, Ling, Chen, Sha, Yu, Wu, Liu, Shengwei, Liu, JingDong, Wang, Xuan, Fan, Xiaomei, Dong, Zhi

“…Ischemic stroke is a complex brain disease regulated by several cell death processes, including apoptosis, autophagy, and ferroptosis. β-Caryophyllene (BCP), a…”
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Royal jelly acid suppresses hepatocellular carcinoma tumorigenicity by inhibiting H3 histone lactylation at H3K9la and H3K14la sites by Xu, Haiying, Li, Lanqing, Wang, Shunshun, Wang, Zijun, Qu, Linghang, Wang, Chunli, Xu, Kang

“…Human hepatocellular carcinoma (HCC) features include enhanced glycolysis and elevated lactate concentrations. Accumulation of lactate during metabolism…”
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Shaoyao decoction attenuates DSS-induced ulcerative colitis, macrophage and NLRP3 inflammasome activation through the MKP1/NF-κB pathway by Wei, Yuan-yuan, Fan, Yi-meng, Ga, Yu, Zhang, Yan-nan, Han, Jun-cheng, Hao, Zhi-hui

“…Shaoyao decoction (SYD), a traditional Chinese medicine prescription that originated in the Jin-Yuan Dynasty, has shown effects in treating ulcerative colitis…”
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Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells by Ooko, Edna, Saeed, Mohamed E.M., Kadioglu, Onat, Sarvi, Shabnam, Colak, Merve, Elmasaoudi, Kaoutar, Janah, Rabab, Greten, Henry J., Efferth, Thomas

“…Apoptosis and other forms of cell death have been intensively investigated in the past years to explain the mode of action of synthetic anticancer drugs and…”
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Ginsenoside Rd: A promising natural neuroprotective agent by Chen, Yu-Ying, Liu, Qiu-Ping, An, Pei, Jia, Min, Luan, Xin, Tang, Jian-Yuan, Zhang, Hong

“…Neurological diseases seriously affect human health, which are arousing wider attention, and it is a great challenge to discover neuroprotective drugs with…”
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Salidroside stimulates the Sirt1/PGC-1α axis and ameliorates diabetic nephropathy in mice by Xue, Haiyan, Li, Peipei, Luo, Yishu, Wu, Chuwen, Liu, Yue, Qin, Xiaogang, Huang, Xinzhong, Sun, Cheng

“…Salidroside, an active component from Traditional Chinese Medicine Rhodiola rosea L., has various pharmacological functions including anti-inflammatory,…”
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Dietary polyphenols in chemoprevention and synergistic effect in cancer: Clinical evidences and molecular mechanisms of action by Patra, Srimanta, Pradhan, Biswajita, Nayak, Rabindra, Behera, Chhandashree, Das, Surajit, Patra, Samir Kumar, Efferth, Thomas, Jena, Mrutyunjay, Bhutia, Sujit Kumar

“…•Dietary polyphenols regulate molecular cell death pathways and inflammation for cancer prevention.•Polyphenolic drug synergism enhances the anticancer…”
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Phytosterols of marine algae: Insights into the potential health benefits and molecular pharmacology by Hannan, Md. Abdul, Sohag, Abdullah Al Mamun, Dash, Raju, Haque, Md. Nazmul, Mohibbullah, Md, Oktaviani, Diyah Fatimah, Hossain, Md. Tahmeed, Choi, Ho Jin, Moon, Il Soo

“…Marine algae are rich in some unique biologically active secondary metabolites having diverse pharmacological benefits. Of these, sterols comprise a group of…”
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Analytical strategies for the discovery and validation of quality-markers of traditional Chinese medicine by Ren, Jun-ling, Zhang, Ai-Hua, Kong, Ling, Han, Ying, Yan, Guang-Li, Sun, Hui, Wang, Xi-Jun

“…Quality control of traditional Chinese medicine (TCM) is the basis of clinical efficacy. Due to the complexity of TCM, it is difficult to unify the quality…”
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Effect of Coptis chinensis franch and Magnolia officinalis on intestinal flora and intestinal barrier in a TNBS-induced ulcerative colitis rats model by Xie, Qian, Li, Hongyan, Ma, Rong, Ren, Mihong, Li, Yong, Li, Jinxiu, Chen, Hai, Chen, Zhuoping, Gong, Daoyin, Wang, Jian

“…In folk medicine Coptis chinensis Franch (Huanglian in Chinese, HL) and Magnoliae officinalis (Houpo, HP) have been used to treat gastrointestinal disorders…”
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Shikonin, a naphthalene ingredient: Therapeutic actions, pharmacokinetics, toxicology, clinical trials and pharmaceutical researches by Sun, Qiang, Gong, Ting, Liu, Maolun, Ren, Shan, Yang, Han, Zeng, Sha, Zhao, Hui, Chen, Li, Ming, Tianqi, Meng, Xianli, Xu, Haibo

“…Shikonin is one of the major phytochemical components of Lithospermum erythrorhizon (Purple Cromwell), which is a type of medicinal herb broadly utilized in…”
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Shikonin and cisplatin synergistically overcome cisplatin resistance of ovarian cancer by inducing ferroptosis via upregulation of HMOX1 to promote Fe2+ accumulation by Ni, Maowei, Zhou, Jie, Zhu, Zhihui, Xu, Qiang, Yin, Zhuomin, Wang, Yifan, Zheng, Zhiguo, Zhao, Huajun

“…•Shikonin and cisplatin synergistically reduced proliferation and colony formation of cisplatin-resistant OC cells.•Co-treatment with shikonin and cisplatin…”
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Baicalin induces ferroptosis in osteosarcomas through a novel Nrf2/xCT/GPX4 regulatory axis by Wen, Rui-jia, Dong, Xin, Zhuang, Hao-wen, Pang, Feng-xiang, Ding, Shou-chang, Li, Nan, Mai, Yong-xin, Zhou, Shu-ting, Wang, Jun-yan, Zhang, Jin-fang

“…Osteosarcomas (OS) is a kind of malignant bone tumor which occurs primarily in children and adolescents, and the clinical therapeutics remain disappointing. As…”
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