Search Results - "Physiological research"

COVID-19 and the immune system by Paces, J, Strizova, Z, Smrz, D, Cerny, J

“…A close interaction between the virus SARS-CoV-2 and the immune system of an individual results in a diverse clinical manifestation of the COVID-19 disease…”
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Acute lung injury - from pathophysiology to treatment by Mokra, D

“…Acute lung injury is characterized by acute respiratory insufficiency with tachypnea, cyanosis refractory to oxygen, decreased lung compliance, and diffuse…”
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The PI3k/Akt pathway is associated with angiogenesis, oxidative stress and survival of mesenchymal stem cells in pathophysiologic condition in ischemia by Samakova, A, Gazova, A, Sabova, N, Valaskova, S, Jurikova, M, Kyselovic, J

“…Ischemic diseases are characterized by reduced blood supply to a tissue or an organ due to obstruction of blood vessels. The most serious and most common…”
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Serum levels of spexin and kisspeptin negatively correlate with obesity and insulin resistance in women by Kołodziejski, P A, Pruszyńska-Oszmałek, E, Korek, E, Sassek, M, Szczepankiewicz, D, Kaczmarek, P, Nogowski, L, Maćkowiak, P, Nowak, K W, Krauss, H, Strowski, M Z

“…Spexin (SPX) and kisspeptin (KISS) are novel peptides relevant in the context of regulation of metabolism, food intake, puberty and reproduction. Here, we…”
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Lipopolysaccharide-induced memory impairment in rats: a model of Alzheimer's disease by Zakaria, R, Wan Yaacob, W Mh, Othman, Z, Long, I, Ahmad, A H, Al-Rahbi, B

“…Alzheimer's disease (AD) is a primary cause of dementia in the middle-aged and elderly worldwide. Animal models for AD are widely used to study the disease…”
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Quercetin protects against stress-induced anxiety- and depression-like behavior and improves memory in male mice by Samad, N, Saleem, A, Yasmin, F, Shehzad, M A

“…The present study evaluates the protective role of Quercetin (Quer), against immobilization stress- induced anxiety, depression and cognition alteration in…”
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The anti-obesity and health-promoting effects of tea and coffee by Sirotkin, A V, Kolesárová, A

“…This paper reviews provenance, chemical composition and properties of tea (Camelia sinensis L.) and coffee (Coffee arabica, L. and Coffeacaniphora, L.), their…”
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Structure, function, and pharmacology of NMDA receptor channels by Vyklicky, V, Korinek, M, Smejkalova, T, Balik, A, Krausova, B, Kaniakova, M, Lichnerova, K, Cerny, J, Krusek, J, Dittert, I, Horak, M, Vyklicky, L

“…NMDA receptors have received much attention over the last few decades, due to their role in many types of neural plasticity on the one hand, and their…”
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Pathophysiological mechanisms of calcineurin inhibitor-induced nephrotoxicity and arterial hypertension by Hošková, L, Málek, I, Kopkan, L, Kautzner, J

“…Solid organ transplantation is an established treatment modality in patients with end-stage organ damage in cases where other therapeutic options fail. The…”
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Synthetic polymer scaffolds for soft tissue engineering by Janoušková, O

“…Tissue engineering (TE) and regenerative medicine are progressively developed areas due to many novel tissue replacements and implementation strategies…”
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Acrylamide: a common food toxin related to physiological functions and health by Semla, M, Goc, Z, Martiniaková, M, Omelka, R, Formicki, G

“…Acrylamide (AA) is a highly reactive organic compound capable of polymerization to form polyacrylamide, which is commonly used throughout a variety of…”
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Cell-penetrating peptides: a useful tool for the delivery of various cargoes into cells by Böhmová, E, Machová, D, Pechar, M, Pola, R, Venclíková, K, Janoušková, O, Etrych, T

“…Cell-penetrating compounds are substances that enhance the cellular uptake of various molecular cargoes that do not easily cross the cellular membrane. The…”
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The role of skeletal muscle in the pathogenesis of altered concentrations of branched-chain amino acids (valine, leucine, and isoleucine) in liver cirrhosis, diabetes, and other diseases by Holeček, M

“…The article shows that skeletal muscle plays a dominant role in the catabolism of branched-chain amino acids (BCAAs; valine, leucine, and isoleucine) and the…”
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Hepatic Stellate Cell: A Double-Edged Sword in the Liver by Luo, Nianan, Li, Jiangbin, Wei, Yu, Lu, Jianguo, Dong, Rui

“…Hepatic stellate cells (HSCs) are located in the space of Disse, between liver sinusoidal endothelia cells (LSECs) and hepatocytes. They have surprised and…”
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Some current insights into oxidative stress by Ďuračková, Z

“…Oxidative stress is a phenomenon associated with pathogenetic mechanisms of several diseases including atherosclerosis, neurodegenerative diseases, such as…”
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Metabolic cooperation in the ovarian follicle by Fontana, J, Martínková, S, Petr, J, Žalmanová, T, Trnka, J

“…Granulosa cells (GCs) are somatic cells essential for establishing and maintaining bi-directional communication with the oocytes. This connection has a…”
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Effect of aerobic training and resistance training on circulating irisin level and their association with change of body composition in overweight/obese adults: a pilot study by Kim, H-J, Lee, H-J, So, B, Son, J S, Yoon, D, Song, W

“…The novel myokine irisin has been reported as a therapeutic target for metabolic disease. The objective of this study is to reveal the effects of aerobic…”
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Excess of free fatty acids as a cause of metabolic dysfunction in skeletal muscle by Tumova, J, Andel, M, Trnka, J

“…Obesity is often associated with metabolic impairments in peripheral tissues. Evidence suggests an excess of free fatty acids (FFA) as one factor linking…”
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Side effects of amino acid supplements by Holecek, Milan

“…The aim of the article is to examine side effects of increased dietary intake of amino acids, which are commonly used as a dietary supplement. In addition to…”
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The role of AMPK/mTOR signaling pathway in anticancer activity of metformin by Chomanicova, N, Gazova, A, Adamickova, A, Valaskova, S, Kyselovic, J

“…Metformin (MTF) is a widely used drug for the treatment of diabetes mellitus type 2 (DM2) and frequently used as an adjuvant therapy for polycystic ovarian…”
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