Search Results - "Phyo, Aung P."
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Antimalarial Activity of KAF156 in Falciparum and Vivax Malaria
Published in The New England journal of medicine (22-09-2016)“…With the emergence and spread of artemisinin resistance, new therapies for malaria are needed. This study shows that the imidazolopiperazine KAF156, a new…”
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Population genetic correlates of declining transmission in a human pathogen
Published in Molecular ecology (01-01-2013)“…Pathogen control programs provide a valuable, but rarely exploited, opportunity to directly examine the relationship between population decline and population…”
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The risk of Plasmodium vivax parasitaemia after P. falciparum malaria: An individual patient data meta-analysis from the WorldWide Antimalarial Resistance Network
Published in PLoS medicine (19-11-2020)“…There is a high risk of Plasmodium vivax parasitaemia following treatment of falciparum malaria. Our study aimed to quantify this risk and the associated…”
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The haematological consequences of Plasmodium vivax malaria after chloroquine treatment with and without primaquine: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis
Published in BMC medicine (01-08-2019)“…Malaria causes a reduction in haemoglobin that is compounded by primaquine, particularly in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency…”
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The effect of chloroquine dose and primaquine on Plasmodium vivax recurrence: a WorldWide Antimalarial Resistance Network systematic review and individual patient pooled meta-analysis
Published in The Lancet infectious diseases (01-09-2018)“…Chloroquine remains the mainstay of treatment for Plasmodium vivax malaria despite increasing reports of treatment failure. We did a systematic review and…”
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Auditory assessment of patients with acute uncomplicated Plasmodium falciparum malaria treated with three-day mefloquine-artesunate on the north-western border of Thailand
Published in Malaria journal (06-11-2008)“…The use of artemisinin derivatives has increased exponentially with the deployment of artemisinin combination therapy (ACT) in all malarious areas. They are…”
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The efficacy of dihydroartemisinin-piperaquine and artemether-lumefantrine with and without primaquine on Plasmodium vivax recurrence: A systematic review and individual patient data meta-analysis
Published in PLoS medicine (04-10-2019)“…Artemisinin-based combination therapy (ACT) is recommended for uncomplicated Plasmodium vivax malaria in areas of emerging chloroquine resistance. We undertook…”
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An open dataset of Plasmodium vivax genome variation in 1,895 worldwide samples
Published in Wellcome open research (2022)“…This report describes the MalariaGEN Pv4 dataset, a new release of curated genome variation data on 1,895 samples of collected at 88 worldwide locations…”
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Perception of the risk of tobacco use in pregnancy and factors associated with tobacco use in rural areas of Myanmar
Published in Tobacco prevention & cessation (2019)“…Tobacco use is recognized as the most important preventable risk factor for pregnancy complications and undesirable fetal outcomes. This study examined the…”
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Pf7: an open dataset of Plasmodium falciparum genome variation in 20,000 worldwide samples
Published in Wellcome open research (2023)“…We describe the MalariaGEN Pf7 data resource, the seventh release of genome variation data from the MalariaGEN network. It comprises over 20,000 samples from…”
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Genomic epidemiology of artemisinin resistant malaria
Published in eLife (04-03-2016)“…The current epidemic of artemisinin resistant Plasmodium falciparum in Southeast Asia is the result of a soft selective sweep involving at least 20 independent…”
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