Search Results - "Phuong Tran, Thao"
-
1
Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells
Published in Cell death & disease (08-02-2022)“…Small extracellular vesicles (sEVs) play a pivotal role in tumor progression by mediating intercellular communication in the tumor microenvironment (TME)…”
Get full text
Journal Article -
2
Decreasing Salt in Hospital Meals Reduced Energy Intake in Elderly Japanese Inpatients
Published in Journal of Nutritional Science and Vitaminology (30-04-2021)“…Japanese salt consumption is high, about 10 g salt/d. Low salt intake reduces the risk of hypertension and cardiovascular disease. However, saltiness is an…”
Get full text
Journal Article -
3
Impact of the Astaxanthin, Betanin, and EGCG Compounds on Small Oligomers of Amyloid Aβ40 Peptide
Published in Journal of chemical information and modeling (23-03-2020)“…There is experimental evidence that the astaxanthin, betanin, and epigallocatechin-3-gallate (EGCG) compounds slow down the aggregation kinetics and the…”
Get full text
Journal Article -
4
Searching and designing potential inhibitors for SARS-CoV-2 Mpro from natural sources using atomistic and deep-learning calculations
Published in RSC advances (29-11-2021)“…The spread of severe acute respiratory syndrome coronavirus 2 novel coronavirus (SARS-CoV-2) worldwide has caused the coronavirus disease 2019 (COVID-19)…”
Get full text
Journal Article -
5
Discovery of Conformationally Restricted Human Glutaminyl Cyclase Inhibitors as Potent Anti-Alzheimer’s Agents by Structure-Based Design
Published in Journal of medicinal chemistry (12-09-2019)“…Alzheimer’s disease (AD) is an incurable, progressive neurodegenerative disease whose pathogenesis cannot be defined by one single element but consists of…”
Get full text
Journal Article -
6
Discovery of Potent Human Glutaminyl Cyclase Inhibitors as Anti-Alzheimer’s Agents Based on Rational Design
Published in Journal of medicinal chemistry (23-03-2017)“…Glutaminyl cyclase (QC) has been implicated in the formation of toxic amyloid plaques by generating the N-terminal pyroglutamate of β-amyloid peptides…”
Get full text
Journal Article -
7
Structure-activity relationship of leucyladenylate sulfamate analogues as leucyl-tRNA synthetase (LRS)-targeting inhibitors of Mammalian target of rapamycin complex 1 (mTORC1)
Published in Bioorganic & medicinal chemistry (15-03-2019)“…[Display omitted] Leucyl-tRNA synthetase (LRS) plays an important role in amino acid-dependent mTORC1 signaling, which is known to be associated with cellular…”
Get full text
Journal Article -
8
Nutritional Status and Feeding Practice among Dysphagic Older Adult Inpatients in Vietnam
Published in Journal of Nutritional Science and Vitaminology (30-06-2020)“…The Vietnamese older adult population has increased rapidly on an annual basis and dysphagia has become a common issue. The nutritional status of older adults…”
Get full text
Journal Article -
9
Emerging Role of Circulating Tumor Cells in Gastric Cancer
Published in Cancers (15-03-2020)“…With over 1 million incidence cases and more than 780,000 deaths in 2018, gastric cancer (GC) was ranked as the 5th most common cancer and the 3rd leading…”
Get full text
Journal Article -
10
Prediction of AChE-ligand affinity using the umbrella sampling simulation
Published in Journal of molecular graphics & modelling (01-12-2019)“…Acetylcholinesterase (AChE) is characterized as a key target for designing inhibitors to prevent Alzheimer's disease (AD). The binding free energy of a ligand…”
Get full text
Journal Article -
11
Discovery of simplified leucyladenylate sulfamates as novel leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors
Published in Bioorganic & medicinal chemistry (01-08-2017)“…[Display omitted] Leucyl-tRNA synthetase (LRS) has been reported to be a possible mediator of intracellular amino acids signaling to mTORC1. Given that mTORC1…”
Get full text
Journal Article -
12
In vitro and in silico determination of glutaminyl cyclase inhibitors
Published in RSC advances (19-09-2019)“…Alzheimer's disease (AD) is the most common form of neurodegenerative disease currently. It is widely accepted that AD is characterized by the self-assembly of…”
Get full text
Journal Article -
13
Smoking trajectory and cancer risk: A population-based cohort study
Published in Tobacco induced diseases (01-08-2022)“…INTRODUCTIONSmoking behavior can change with time and lead to different health outcomes. This study explored the trajectory of smoking and its relationship…”
Get full text
Journal Article -
14
Triterpenoids from Celastrus orbiculatus Thunb. inhibit RANKL-induced osteoclast formation and bone resorption via c-Fos signaling
Published in Journal of natural medicines (2021)“…Fourteen triterpenes, lup-20(29)-ene-3β,6β-diol ( 1 ), betulin ( 2 ), lupeol caffeate ( 3 ), 3β-caffeoyloxylup-20(29)-en-6α-ol ( 4 ), betulin-3β-yl-caffeate (…”
Get full text
Journal Article -
15
Anti-cancer Effect of Xao Tam Phan Paramignya trimera Methanol Root Extract on Human Breast Cancer Cell Line MCF-7 in 3D Model
Published in Advances in experimental medicine and biology (01-01-2020)“…Cancer is one of the leading causes of death in the world. A great deal of effort has been made to discover new agents for cancer treatment. Xao tam phan…”
Get more information
Journal Article -
16
New Acetohydrazides Incorporating 2‐Oxoindoline and 4‐Oxoquinazoline: Synthesis and Evaluation of Cytotoxicity and Caspase Activation Activity
Published in Chemistry & biodiversity (01-03-2020)“…In our search for new small molecules activating procaspase‐3, we have designed and synthesized a series of new acetohydrazides incorporating both…”
Get full text
Journal Article -
17
Potent human glutaminyl cyclase inhibitors as potential anti-Alzheimer’s agents: Structure-activity relationship study of Arg-mimetic region
Published in Bioorganic & medicinal chemistry (01-03-2018)“…[Display omitted] Pyroglutamate-modified amyloid β peptides (pGlu-Aβ) are highly neurotoxic and promote the formation of amyloid plaques. The pGlu-Aβ peptides…”
Get full text
Journal Article -
18
Texture-Modified Diets Need to be Improved in Vietnamese Hospitals
Published in The Journal of Medical Investigation (2022)“…Purpose : The aim of this study is to compare the nutritional status of older adult inpatients consuming Texture-Modified Diets (TMD) to older adult inpatients…”
Get full text
Journal Article -
19
Structure-activity relationship investigation of Phe-Arg mimetic region of human glutaminyl cyclase inhibitors
Published in Bioorganic & medicinal chemistry (23-07-2018)“…[Display omitted] Glutamyl cyclase (QC) is a promising therapeutic target because of its involvement in the pathogenesis of Alzheimer’s disease. In this study,…”
Get full text
Journal Article -
20
Okara Improved Blood Glucose Level in Vietnamese with Type 2 Diabetes Mellitus
Published in Journal of Nutritional Science and Vitaminology (28-02-2019)“…Diabetes mellitus (DM) has been increasing rapidly in Vietnam. We hypothesized that the main reason may be low fiber intake. Regarding sources, fiber comes…”
Get full text
Journal Article