Search Results - "Phung Khanh Lam"
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A Randomized, Double-Blind Placebo Controlled Trial of Balapiravir, a Polymerase Inhibitor, in Adult Dengue Patients
Published in The Journal of infectious diseases (01-05-2013)“…Background. Dengue is the most common arboviral infection of humans. There are currently no specific treatments for dengue. Balapiravir is a prodrug of a…”
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2
Quantifying antimicrobial access and usage for paediatric diarrhoeal disease in an urban community setting in Asia
Published in Journal of antimicrobial chemotherapy (01-09-2018)“…Antimicrobial-resistant infections are a major global health issue. Ease of antimicrobial access in developing countries is proposed to be a key driver of the…”
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3
Excess body weight and age associated with the carriage of fluoroquinolone and third-generation cephalosporin resistance genes in commensal Escherichia coli from a cohort of urban Vietnamese children
Published in Journal of medical microbiology (01-10-2018)“…Antimicrobial-resistant bacterial infections in low- and middle-income countries (LMICs) are a well-established global health issue. We aimed to assess the…”
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4
Factors associated with a low prevalence of exclusive breastfeeding during hospital stay in urban and semi-rural areas of southern Vietnam
Published in International breastfeeding journal (19-10-2018)“…There is a paucity of data regarding risk factors associated with suboptimal breastfeeding practices in urbanized areas of low-middle income countries (LMICs)…”
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5
Learning meaningful latent space representations for patient risk stratification: Model development and validation for dengue and other acute febrile illness
Published in Frontiers in digital health (22-02-2023)“…Increased data availability has prompted the creation of clinical decision support systems. These systems utilise clinical information to enhance health care…”
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6
Clinical prognostic models for severe dengue: a systematic review protocol
Published in Wellcome open research (2019)“…Dengue is a common mosquito-borne, with high morbidity rates recorded in the annual. Dengue contributes to a major disease burden in many tropical countries…”
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7
A review of transition experiences in perinatally and behaviourally acquired HIV‐1 infection; same, same but different?
Published in Journal of the International AIDS Society (01-05-2017)“…Introduction: Despite sharing common psychosocial and developmental experiences, adolescents living with perinatally and behaviourally acquired HIV‐1 infection…”
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Lovastatin for the Treatment of Adult Patients With Dengue: A Randomized, Double-Blind, Placebo-Controlled Trial
Published in Clinical infectious diseases (15-02-2016)“…Background. Dengue endangers billions of people in the tropical world, yet no therapeutic is currently available. In part, the severe manifestations of dengue…”
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Higher Plasma Viremia in the Febrile Phase Is Associated With Adverse Dengue Outcomes Irrespective of Infecting Serotype or Host Immune Status: An Analysis of 5642 Vietnamese Cases
Published in Clinical infectious diseases (15-06-2021)“…Abstract Background One of the generally accepted constructs of dengue pathogenesis is that clinical disease severity is at least partially dependent upon…”
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10
C-reactive protein as a potential biomarker for disease progression in dengue: a multi-country observational study
Published in BMC medicine (17-02-2020)“…Dengue infection can cause a wide spectrum of clinical outcomes. The severe clinical manifestations occur sufficiently late in the disease course, during day…”
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Clinical Characteristics of Dengue Shock Syndrome in Vietnamese Children: A 10-Year Prospective Study in a Single Hospital
Published in Clinical infectious diseases (01-12-2013)“…Background. Dengue shock syndrome (DSS) is a severe manifestation of dengue virus infection that particularly affects children and young adults. Despite its…”
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12
Methods to discriminate primary from secondary dengue during acute symptomatic infection
Published in BMC infectious diseases (07-08-2018)“…Dengue virus infection results in a broad spectrum of clinical outcomes, ranging from asymptomatic infection through to severe dengue. Although prior infection…”
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13
Burden of Postinfectious Symptoms after Acute Dengue, Vietnam
Published in Emerging infectious diseases (01-01-2023)“…We assessed predominantly pediatric patients in Vietnam with dengue and other febrile illness 3 months after acute illness. Among dengue patients, 47% reported…”
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14
The value of daily platelet counts for predicting dengue shock syndrome: Results from a prospective observational study of 2301 Vietnamese children with dengue
Published in PLoS neglected tropical diseases (27-04-2017)“…Dengue is the most important mosquito-borne viral infection to affect humans. Although it usually manifests as a self-limited febrile illness, complications…”
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15
The compensatory reserve index predicts recurrent shock in patients with severe dengue
Published in BMC medicine (07-04-2022)“…Dengue shock syndrome (DSS) is one of the major clinical phenotypes of severe dengue. It is defined by significant plasma leak, leading to intravascular volume…”
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16
Association of Microvascular Function and Endothelial Biomarkers With Clinical Outcome in Dengue: An Observational Study
Published in The Journal of infectious diseases (01-09-2016)“…Background. The hallmark of severe dengue is increased microvascular permeability, but alterations in the microcirculation and their evolution over the course…”
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Dengue viremia kinetics and effects on platelet count and clinical outcomes: An analysis of 2340 patients from Vietnam
Published in eLife (21-06-2024)“…Viremia is a critical factor in understanding the pathogenesis of dengue infection, but limited data exist on viremia kinetics. This study aimed to investigate…”
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Endothelial Nitric Oxide Pathways in the Pathophysiology of Dengue: A Prospective Observational Study
Published in Clinical infectious diseases (01-11-2017)“…Dengue can cause increased vascular permeability that may lead to hypovolemic shock. Endothelial dysfunction may underlie this; however, the association of…”
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The seroincidence of childhood Shigella sonnei infection in Ho Chi Minh City, Vietnam
Published in PLoS neglected tropical diseases (01-10-2023)“…Shigella sonnei is a pathogen of growing global importance as a cause of diarrhoeal illness in childhood, particularly in transitional low-middle income…”
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Combination of inflammatory and vascular markers in the febrile phase of dengue is associated with more severe outcomes
Published in eLife (22-06-2021)“…Early identification of severe dengue patients is important regarding patient management and resource allocation. We investigated the association of 10…”
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