Search Results - "Phong, Binh"
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Cutting Edge: Murine Mast Cells Rapidly Modulate Metabolic Pathways Essential for Distinct Effector Functions
Published in The Journal of immunology (1950) (15-01-2017)“…There is growing appreciation that cellular metabolic and bioenergetic pathways do not play merely passive roles in activated leukocytes. Rather, metabolism…”
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Tim-3 enhances FcεRI-proximal signaling to modulate mast cell activation
Published in The Journal of experimental medicine (14-12-2015)“…T cell (or transmembrane) immunoglobulin and mucin domain protein 3 (Tim-3) has attracted significant attention as a novel immune checkpoint receptor (ICR) on…”
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T cell receptor-dependent activation of mTOR signaling in T cells is mediated by Carma1 and MALT1, but not Bcl10
Published in Science signaling (10-06-2014)“…Signaling to the mechanistic target of rapamycin (mTOR) regulates diverse cellular processes, including protein translation, cellular proliferation,…”
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Nontypeable Haemophilus influenzae Type IV Pilus Mediates Augmented Adherence to Rhinovirus-Infected Human Airway Epithelial Cells
Published in Infection and immunity (19-08-2020)“…Human rhinovirus (hRV) is frequently detected in the upper respiratory tract, and symptomatic infection is associated with an increased nasopharyngeal…”
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IgE-activated mast cells enhance TLR4-mediated antigen-specific CD4+ T cell responses
Published in Scientific reports (06-05-2021)“…Mast cells are potent mediators of allergy and asthma, yet their role in regulating adaptive immunity remains ambiguous. On the surface of mast cells, the…”
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TIM-3–Expressing Mast Cells Are Present in Chronic Rhinosinusitis with Nasal Polyps
Published in Otolaryngology-head and neck surgery (01-09-2018)“…Objectives To identify whether TIM-3 expression is present in the mast cell population within nasal polyps and to determine its correlation with clinical…”
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Regulation of Fertility, Survival, and Cuticle Collagen Function by the Caenorhabditis elegans eaf-1 and ell-1 Genes
Published in The Journal of biological chemistry (14-10-2011)“…EAF2, an androgen-regulated protein, interacts with members of the ELL (eleven-nineteen lysine-rich leukemia) transcription factor family and also acts as a…”
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Mast cell activation is enhanced by Tim1:Tim4 interaction but not by Tim-1 antibodies
Published in F1000 research (2016)“…Polymorphisms in the T cell (or transmembrane) immunoglobulin and mucin domain 1 ( TIM-1 ) gene, particularly in the mucin domain, have been associated with…”
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Modulation of mast cell function by TIM-3 signaling (HYP3P.351)
Published in The Journal of immunology (1950) (01-05-2014)“…Transmembrane, immunoglobulin and mucin domain-3 (Tim-3) is an inducible negative regulator of Th1 function and anti-tumor immune responses. Recent studies…”
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Modulation of mast cell function by TIM-1 signaling (177.4)
Published in The Journal of immunology (1950) (01-05-2012)“…Transmembrane, immunoglobulin and mucin domain (TIM)-1 belongs to a family of transmembrane proteins with emerging roles in immune modulation. As a putative…”
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Mast cell activation enhances the TLR4-mediated antigen-specific CD4 T cell response
Published in The Journal of immunology (1950) (01-05-2020)“…Mast cells are important immune mediators located at host environment interfaces and are most well-known as the major mediators of allergy and asthma. When…”
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Akt Fine-tunes NF-κB-dependent Gene Expression during T Cell Activation
Published in The Journal of biological chemistry (14-10-2011)“…Activation of the NF-κB signaling pathway is critical for leukocyte activation and development. Although previous studies suggested a role for the Akt kinase…”
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Murine mast cells rapidly modulate metabolic pathways essential for distinct effector functions1
Published in The Journal of immunology (1950) (14-12-2016)“…There is growing appreciation that cellular metabolic and bioenergetic pathways do not play merely passive roles in activated leukocytes. Rather, metabolism…”
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Journal Article -
14
TIM polymorphisms—genetics and function
Published in Genes and immunity (01-12-2011)“…The transmembrane immunoglobulin and mucin domain (TIM) family was identified more than a decade ago. Although the founding member of the family was first…”
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Journal Article -
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Mast cell activation is enhanced by Tim1:Tim4 interaction but not by Tim-1 antibodies
Published in F1000 research (2016)“…Polymorphisms in the ( ) gene, particularly in the mucin domain, have been associated with atopy and allergic diseases in mice and human. Genetic- and…”
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Journal Article -
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Regulation of mast cell function by TIM-1 and TIM-3 signaling
Published 01-01-2016“…The T cell (or transmembrane) immunoglobulin and mucin domain (TIM) family proteins have attracted significant attention as novel immune regulators. Tim-3 is…”
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Dissertation