Search Results - "Pho, Mylan"
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A population-based study of tumor gene expression and risk of breast cancer death among lymph node-negative patients
Published in Breast cancer research : BCR (01-01-2006)“…The Oncotype DX assay was recently reported to predict risk for distant recurrence among a clinical trial population of tamoxifen-treated patients with lymph…”
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Journal Article -
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Whole transcriptome RNA-Seq analysis of breast cancer recurrence risk using formalin-fixed paraffin-embedded tumor tissue
Published in PloS one (13-07-2012)“…RNA biomarkers discovered by RT-PCR-based gene expression profiling of archival formalin-fixed paraffin-embedded (FFPE) tissue form the basis for widely used…”
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Journal Article -
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Analytical Validation of the Oncotype DX Genomic Diagnostic Test for Recurrence Prognosis and Therapeutic Response Prediction in Node-Negative, Estrogen Receptor-Positive Breast Cancer
Published in Clinical chemistry (Baltimore, Md.) (01-06-2007)“…Oncotype DX is a clinically validated, high-complexity, multianalyte reverse transcription-PCR genomic test that predicts the likelihood of breast cancer…”
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Utilization of New Technologies in Drug Trials and Discovery
Published in Drug metabolism and disposition (01-04-2001)“…It has become widely accepted that individual genetic variation is a prime determinant in both disease susceptibility and toxic response to therapeutic agents…”
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Journal Article Conference Proceeding -
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Measurement of Gene Expression in Archival Paraffin-Embedded Tissues: Development and Performance of a 92-Gene Reverse Transcriptase-Polymerase Chain Reaction Assay
Published in The American journal of pathology (01-01-2004)“…Throughout the last decade many laboratories have shown that mRNA levels in formalin-fixed and paraffin-embedded (FPE) tissue specimens can be quantified by…”
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Journal Article -
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Abstract 2160: New prognostic breast cancer biomarkers selected from formalin fixed tissue RNA samples after whole transcriptome amplification
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract RT-PCR-based gene expression profiling in archival FFPE tissues with associated clinical records is clinically important in oncology, as evidenced by…”
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Journal Article -
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Rt-PCR gene expression profiling of RNA from paraffin-embedded tissues prepared using a range of different fixatives and conditions
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2011)“…Although RNA is isolated from archival fixed tissues routinely for reverse transcription polymerase chain reaction (RT-PCR) and microarray analyses to identify…”
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Extension of a pilot study : Impact from the cytochrome P450 2D6 polymorphism on outcome and costs associated with severe mental illness
Published in Journal of clinical psychopharmacology (01-04-2000)“…The influence of cytochrome P450 2D6 (CYP2D6) genetic variability was examined in psychiatric inpatients by evaluating adverse drug events (ADEs), hospital…”
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Journal Article -
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Tumor marker discovery by expression profiling RNA from formalin fixed paraffin embedded tissues
Published in Methods in molecular biology (Clifton, N.J.) (2009)“…Clear identification among early-stage cancer patients of those at highest risk of having metastatic disease would be of great benefit in treatment planning…”
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Journal Article -
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In Situ Synthesis of Oligonucleotide Arrays by Using Surface Tension
Published in Journal of the American Chemical Society (19-09-2001)“…This work describes the in situ synthesis of oligonucleotide arrays on glass surfaces. These arrays are composed of features defined and separated by…”
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Journal Article -
11
Measurement of Gene Expression in Archival Paraffin-Embedded Tissues
Published in The American journal of pathology (2004)“…Throughout the last decade many laboratories have shown that mRNA levels in formalin-fixed and paraffin-embedded (FPE) tissue specimens can be quantified by…”
Get full text
Journal Article