Search Results - "Phillips, T M"
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1
Influence of a change in activity regime on femoral bone architecture and failure behaviour
Published in PloS one (29-04-2024)“…The incidence and morbidity of femoral fractures increases drastically with age. Femoral architecture and associated fracture risk are strongly influenced by…”
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2
Estimation of the firing behaviour of a complete motoneuron pool by combining electromyography signal decomposition and realistic motoneuron modelling
Published in PLoS computational biology (01-09-2022)“…Our understanding of the firing behaviour of motoneuron (MN) pools during human voluntary muscle contractions is currently limited to electrophysiological…”
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3
Motoneuron-driven computational muscle modelling with motor unit resolution and subject-specific musculoskeletal anatomy
Published in PLoS computational biology (01-12-2023)“…The computational simulation of human voluntary muscle contraction is possible with EMG-driven Hill-type models of whole muscles. Despite impactful…”
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4
Mathematical relationships between spinal motoneuron properties
Published in eLife (18-07-2022)“…Our understanding of the behaviour of spinal alpha-motoneurons (MNs) in mammals partly relies on our knowledge of the relationships between MN membrane…”
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5
Function and failure of the fetal membrane: Modelling the mechanics of the chorion and amnion
Published in PloS one (28-03-2017)“…The fetal membrane surrounds the fetus during pregnancy and is a thin tissue composed of two layers, the chorion and the amnion. While rupture of this membrane…”
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6
Consideration of multiple load cases is critical in modelling orthotropic bone adaptation in the femur
Published in Biomechanics and modeling in mechanobiology (01-10-2016)“…Functional adaptation of the femur has been investigated in several studies by embedding bone remodelling algorithms in finite element (FE) models, with…”
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7
Modeling the biomechanics of fetal movements
Published in Biomechanics and modeling in mechanobiology (01-08-2016)“…Fetal movements in the uterus are a natural part of development and are known to play an important role in normal musculoskeletal development. However, very…”
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8
Informing phenomenological structural bone remodelling with a mechanistic poroelastic model
Published in Biomechanics and modeling in mechanobiology (01-02-2016)“…Studies suggest that fluid motion in the extracellular space may be involved in the cellular mechanosensitivity at play in the bone tissue adaptation process…”
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9
Enhancing energy absorption through sequential instabilities in mechanical metamaterials
Published in Royal Society open science (30-08-2023)“…Structural components designed to absorb energy and shield a more valuable structure ideally require mechanical properties that combine a relatively high…”
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10
A novel computational framework for deducing muscle synergies from experimental joint moments
Published in Frontiers in computational neuroscience (03-12-2014)“…Prior experimental studies have hypothesized the existence of a "muscle synergy" based control scheme for producing limb movements and locomotion in…”
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11
Generative deep learning applied to biomechanics: A new augmentation technique for motion capture datasets
Published in Journal of biomechanics (01-11-2022)“…Deep learning biomechanical models perform optimally when trained with large datasets, however these can be challenging to collect in gait labs, while limited…”
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12
Stresses and strains on the human fetal skeleton during development
Published in Journal of the Royal Society interface (01-01-2018)“…Mechanical forces generated by fetal kicks and movements result in stimulation of the fetal skeleton in the form of stress and strain. This stimulation is…”
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13
Neonatal cytokines and coagulation factors in children with cerebral palsy
Published in Annals of neurology (01-10-1998)“…We explored the association of inflammatory mediators and markers of autoimmune and coagulation disorders with cerebral palsy (CP), examining 53 analytes in…”
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14
Reliability and minimal detectable change of the 'Imperial Spine' marker set for the evaluation of spinal and lower limb kinematics in adults
Published in BMC research notes (22-10-2020)“…As a step towards the comprehensive evaluation of movement in patients with low back pain, the aim of this study is to design a marker set (three rigid segment…”
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15
An open source lower limb model: Hip joint validation
Published in Journal of biomechanics (11-08-2011)“…Abstract Musculoskeletal lower limb models have been shown to be able to predict hip contact forces (HCFs) that are comparable to in vivo measurements obtained…”
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16
Maintaining Bone Health in the Lumbar Spine: Routine Activities Alone Are Not Enough
Published in Frontiers in bioengineering and biotechnology (19-05-2021)“…Public health organisations typically recommend a minimum amount of moderate intensity activities such as walking or cycling for two and a half hours a week,…”
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Association Between Combat-Related Traumatic Injury and Skeletal Health: Bone Mineral Density Loss Is Localized and Correlates With Altered Loading in Amputees: the Armed Services Trauma Rehabilitation Outcome (ADVANCE) Study
Published in Journal of bone and mineral research (01-09-2023)“…The association between combat-related traumatic injury (CRTI) and bone health is uncertain. A disproportionate number of lower limb amputees from the Iraq and…”
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18
Immunologic function and survival in hemodialysis patients
Published in Kidney international (01-07-1998)“…Immunologic function and survival in hemodialysis patients. Although the medical determinants of mortality in patients with end-stage renal disease (ESRD)…”
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19
Microscale poroelastic metamodel for efficient mesoscale bone remodelling simulations
Published in Biomechanics and modeling in mechanobiology (01-12-2017)“…Bone functional tissue adaptation is a multiaspect physiological process driven by interrelated mechanical and biological stimuli which requires the combined…”
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20
Interleukin-1β Release in the Supraoptic Nucleus Area During Osmotic Stimulation Requires Neural Function
Published in Journal of neuroendocrinology (01-11-2008)“…Interleukin (IL)‐1β is present throughout the magnocellular neuroendocrine system and co‐depletes with oxytocin and vasopressin from the neural lobe during…”
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