Search Results - "Phillips, Sarah E."
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1
Brown adipose tissue thermogenesis in polycystic ovary syndrome
Published in Clinical endocrinology (Oxford) (01-03-2019)“…Summary Objective Polycystic ovary syndrome (PCOS) is associated with increased obesity with a greater propensity to weight gain and a lack of sustainable…”
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2
Antibody-Based Imaging of Bioreductive Prodrug Release in Hypoxia
Published in JACS Au (27-11-2023)“…Regions of hypoxia occur in most tumors and are a predictor of poor patient prognosis. Hypoxia-activated prodrugs (HAPs) provide an ideal strategy to target…”
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3
The role of β2 adrenergic receptor on infection development after ischaemic stroke
Published in Brain, behavior, & immunity. Health (01-12-2021)“…Mechanisms underlying post-stroke immune impairments and subsequent development of fatal lung infection have been suggested to involve multiple pathways,…”
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4
Comparable Attenuation of Sympathetic Nervous System Activity in Obese Subjects with Normal Glucose Tolerance, Impaired Glucose Tolerance, and Treatment Naïve Type 2 Diabetes following Equivalent Weight Loss
Published in Frontiers in physiology (03-11-2016)“…Elevated sympathetic nervous system (SNS) activity is a characteristic of obesity and type 2 diabetes (T2D) that contributes to target organ damage and…”
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5
Characteristics and physiological basis of falls in ventricular outputs after immediate cord clamping at delivery in preterm fetal lambs
Published in The Journal of physiology (01-08-2021)“…Key points Controversy exists about the physiological mechanism(s) underlying decreases in cardiac output after immediate clamping of the umbilical cord at…”
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Beta-blockade enhances anthracycline control of metastasis in triple-negative breast cancer
Published in Science translational medicine (26-04-2023)“…Beta-adrenergic blockade has been associated with improved cancer survival in patients with triple-negative breast cancer (TNBC), but the mechanisms of these…”
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7
Circulating epinephrine is not required for chronic stress to enhance metastasis
Published in Psychoneuroendocrinology (01-01-2019)“…•Chronic stress enhances cancer progression including metastasis in mouse models of breast cancer.•Splanchnic nerve lesioning eliminates epinephrine release…”
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Blunted sympathoadrenal activation accompanies hemodynamic stability after early ventilation and delayed cord clamping at birth in preterm lambs
Published in Pediatric research (01-10-2019)“…Background As surges in circulating norepinephrine and epinephrine have chronotropic, pressor, and inotropic effects, we tested the hypothesis that blunted…”
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Greater sympathoadrenal activation with longer preventilation intervals after immediate cord clamping increases hemodynamic lability at birth in preterm lambs
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-06-2017)“…This study tested the hypothesis that varying degrees of hemodynamic fluctuations seen after birth following immediate cord clamping were related to…”
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10
Effects of Moxonidine and Low‐Calorie Diet: Cardiometabolic Benefits from Combination of Both Therapies
Published in Obesity (Silver Spring, Md.) (01-11-2017)“…Objective Because sympathetic nervous system activity plays a detrimental role in metabolic and cardiovascular health, this study compared the effects of a…”
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Arabidopsis thaliana T-DNA Mutants Implicate GAUT Genes in the Biosynthesis of Pectin and Xylan in Cell Walls and Seed Testa
Published in Molecular plant (01-09-2009)“…Galacturonosyltransferase 1 (GAUT1) is an α1,4-D-galacturonosyltransferase that transfers galacturonic acid from uridine 5′-diphosphogalacturonic acid onto the…”
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Arterial Norepinephrine Concentration is Inversely and Independently Associated With Insulin Clearance in Obese Individuals With Metabolic Syndrome
Published in The journal of clinical endocrinology and metabolism (01-04-2015)“…Context: Impaired insulin clearance contributes to the hyperinsulinemia of obesity, yet relatively little is known concerning the pathophysiological…”
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13
Neck Circumference Is Associated with Muscle Sympathetic Nerve Activity in Overweight and Obese Men but Not Women
Published in Frontiers in physiology (06-04-2017)“…Neck circumference (NC) is a predictor of cardiometabolic risk. The objective of this study was to explore the relationship of NC to muscle sympathetic nerve…”
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14
Reduction in peripheral vascular resistance predicts improvement in insulin clearance following weight loss
Published in Cardiovascular diabetology (22-08-2015)“…The hyperinsulinemia of obesity is a function of both increased pancreatic insulin secretion and decreased insulin clearance, and contributes to cardiovascular…”
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