Search Results - "Phillips, RE"

Treatment of bioprosthetic heart valve tissue with long chain alcohol solution to lower calcification potential by Pathak, Chandrashekar P., Adams, Alan K., Simpson, Tom, Phillips Jr, Richard E., Moore, Mark A.

“…The use of glutaraldehyde‐treated biological tissue in heart valve substitutes is an important option in the treatment of heart valve disease. These devices…”
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P16-56 LB. Novel tetramer technology for the detection of high affinity CD8 T cells by Hoffmann, M, Hickling, S, Filby, A, Wilburg, C, Cole, D, Turner, A, Sims, S, McLean, A, Sewell, A, Klenerman, P, Frater, J, Phillips, R E

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G553(P) ‘back to school’: the psychosocial impact on children with cancer by Im, YR, Phillips, RE, Gite, A

“…BackgroundPrevious studies have shown that the experience of having cancer impacts on various aspects of a child’s mental and physical health and abilities…”
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Memory Inflation: Continuous Accumulation of Antiviral CD8+ T Cells Over Time by Karrer, Urs, Sierro, Sophie, Wagner, Markus, Oxenius, Annette, Hengel, Hartmut, Koszinowski, Ulrich H, Phillips, Rodney E, Klenerman, Paul

“…CD8+ T lymphocytes play an important role in the control of intracellular pathogens during both acute and persistent infections. This is particularly true in…”
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Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses by Kelleher, A D, Long, C, Holmes, E C, Allen, R L, Wilson, J, Conlon, C, Workman, C, Shaunak, S, Olson, K, Goulder, P, Brander, C, Ogg, G, Sullivan, J S, Dyer, W, Jones, I, McMichael, A J, Rowland-Jones, S, Phillips, R E

“…The immune response to HIV-1 in patients who carry human histocompatibility leukocyte antigen (HLA)-B27 is characterized by an immunodominant response to an…”
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Early Highly Active Antiretroviral Therapy for Acute HIV-1 Infection Preserves Immune Function of CD8+and CD4+T Lymphocytes by Oxenius, Annette, Price, David A., Easterbrook, Philippa J., O'Callaghan, Christopher A., Kelleher, Anthony D., Whelan, Joseph A., Sontag, Glenn, Sewell, Andrew K., Phillips, Rodney E.

“…Highly active antiretroviral therapy (HAART) has been advocated for the management of primary HIV-1 infection without clear understanding of its immunological…”
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Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS by Goulder, Philip J.R, Phillips, Rodney E, Colbert, Robert A, McAdam, Stephen, Ogg, Graham, Nowak, Martin A, Giangrande, Paul, Luzzi, Graz, Morgana, Barbara, Edwards, Anne, McMichael, Andrew J, Rowland-Jones, Sarah

“…The precise role played by HIV-specific cytotoxic T lymphocytes (CTL) in HIV infection remains controversial. Despite strong CTL responses being generated…”
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Stimulation of HIV-Specific Cellular Immunity by Structured Treatment Interruption Fails to Enhance Viral Control in Chronic HIV Infection by Oxenius, Annette, Price, David A., Günthard, Huldrych F., Dawson, Sara J., Fagard, Catherine, Perrin, Luc, Fischer, Marek, Weber, Rainer, Plana, Montserrat, Garcia, Felipe, Hirschel, Bernard, McLean, Angela, Phillips, Rodney E.

“…Potent antiretroviral therapy (ART) suppresses HIV-1 viral replication and results in decreased morbidity and mortality. However, prolonged treatment is…”
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Ultrasensitive Detection and Phenotyping of CD4+ T Cells with Optimized HLA Class II Tetramer Staining by Scriba, Thomas J, Purbhoo, Marco, Day, Cheryl L, Robinson, Nicola, Fidler, Sarah, Fox, Julie, Weber, Jonathan N, Klenerman, Paul, Sewell, Andrew K, Phillips, Rodney E

“…HLA class I tetramers have revolutionized the study of Ag-specific CD8+ T cell responses. Technical problems and the rarity of Ag-specific CD4+ Th cells have…”
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Positive Selection of HIV-1 Cytotoxic T Lymphocyte Escape Variants during Primary Infection by Price, David A., Philip J. R. Goulder, Klenerman, Paul, Sewell, Andrew K., Easterbrook, Philippa J., Troop, Maxine, Charles R. M. Bangham, Phillips, Rodney E.

“…Cytotoxic T lymphocytes (CTLs) are thought to play a crucial role in the termination of the acute primary HIV-1 syndrome, but clear evidence for this…”
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Expansion of Protective CD8+ T-Cell Responses Driven by Recombinant Cytomegaloviruses by KARRER, Urs, WAGNER, Markus, SIERRO, Sophie, OXENIUS, Annette, HENGEL, Hartmut, DUMRESE, Tilman, FREIGANG, Stefan, KOSZINOWSKI, Ulrich H, PHILLIPS, Rodney E, KLENERMAN, Paul

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Tenacious Binding of Fibrinogen and Albumin to Pyrolite Carbon and Biomer by Chinn, Joseph A., Phillips, Jr, Richard E., Lew, Kenneth R., Horbett, Thomas A.

“…Adsorption of bovine fibrinogen from dilute plasma and human serum albumin (HSA) from buffered HSA solution to low-temperature isotropic (LTI) pyrolytic carbon…”
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ESCAPE OF HUMAN IMMUNODEFICIENCY VIRUS FROM IMMUNE CONTROL by McMichael, Andrew J, Phillips, Rodney E

“…Cytotoxic T lymphocytes (CTL) play a crucial role in the attempt to control infection with human immunodeficiency virus (HIV). Variation in epitopes recognized…”
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Modelling the Evolution and Spread of HIV Immune Escape Mutants by Fryer, H.R, Frater, J, Duda, A, Roberts, M.G, SPARTAC Trial Investigators, Phillips RE, McLean, A.R, Pumarola Suñé, Tomás

“…During infection with human immunodeficiency virus (HIV), immune pressure from cytotoxic T-lymphocytes (CTLs) selects for viral mutants that confer escape from…”
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CD8+ T Cell Epitope-Flanking Mutations Disrupt Proteasomal Processing of HIV-1 Nef by Milicic, Anita, Price, David A, Zimbwa, Peter, Booth, Bruce L, Brown, Helen L, Easterbrook, Philippa J, Olsen, Kara, Robinson, Nicola, Gileadi, Uzi, Sewell, Andrew K, Cerundolo, Vincenzo, Phillips, Rodney E

“…CTL play a critical role in the control of HIV and SIV. However, intrinsic genetic instability enables these immunodeficiency viruses to evade detection by CTL…”
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The Human CD8 Coreceptor Effects Cytotoxic T Cell Activation and Antigen Sensitivity Primarily by Mediating Complete Phosphorylation of the T Cell Receptor ζ Chain by Purbhoo, Marco A., Boulter, Jonathan M., Price, David A., Vuidepot, Anne-Lise, Hourigan, Christopher S., Dunbar, P. Rod, Olson, Kara, Dawson, Sara J., Phillips, Rodney E., Jakobsen, Bent K., Bell, John I., Sewell, Andrew K.

“…Recognition of antigen by cytotoxic T lymphocytes (CTL) is determined by interaction of both the T cell receptor and its CD8 coreceptor with peptide-major…”
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Immunology taught by Darwin by Phillips, Rodney E

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Quantifiable Cytotoxic T Lymphocyte Responses and HLA-Related Risk of Progression to AIDS by Scherer, Almut, Frater, John, Oxenius, Annette, Agudelo, Juliet, Price, David A., Günthard, Huldrych F., Barnardo, Martin, Perrin, Luc, Hirschel, Bernard, Phillips, Rodney E., McLean, Angela R., The Swiss HIV Cohort Study, May, Robert

“…There are significant associations between possession of certain HLA class I alleles and rate of progression to AIDS. Immunological data provide an explanatory…”
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Population genetic estimation of the loss of genetic diversity during horizontal transmission of HIV-1 by Edwards, Charles T T, Holmes, Edward C, Wilson, Daniel J, Viscidi, Raphael P, Abrams, Elaine J, Phillips, Rodney E, Drummond, Alexei J

“…Genetic diversity of the human immunodeficiency virus type 1 (HIV-1) population within an individual is lost during transmission to a new host. The demography…”
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Loss of viral control in early HIV-1 infection Is temporally associated with sequential escape from CD8+ T cell responses and decrease in HIV-1-specific CD4+ and CD8+ T cell frequencies by Oxenius, Annette, Price, David A., Trkola, Alexandra, Edwards, Charles, Gostick, Emma, Zhang, Hua-Tang, Easterbrook, Philippa J., Tun, Tin, Johnson, Andrew, Waters, Anele, Holmes, Edward C., Phillips, Rodney E.

“…The outcome of human immunodeficiency virus type 1 (HIV-1) infection is related to the set-point plasma virus load (pVL) that emerges after primary HIV-1…”
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