Search Results - "Phillips, P. J"
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1
A prospective diffusion tensor imaging study in mild traumatic brain injury
Published in Neurology (23-02-2010)“…Only a handful of studies have investigated the nature, functional significance, and course of white matter abnormalities associated with mild traumatic brain…”
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2
Four-Month Moxifloxacin-Based Regimens for Drug-Sensitive Tuberculosis
Published in The New England journal of medicine (23-10-2014)“…One approach to improving tuberculosis therapy is to shorten the duration from 6 months to 4 months. In this trial in over 1900 patients with smear-positive…”
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3
High-Dose Rifapentine with Moxifloxacin for Pulmonary Tuberculosis
Published in The New England journal of medicine (23-10-2014)“…In this report from sub-Saharan Africa, a 4-month regimen of moxifloxacin and rifapentine for pulmonary tuberculosis was not as beneficial as two 6-month…”
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4
An evaluation of culture results during treatment for tuberculosis as surrogate endpoints for treatment failure and relapse
Published in PloS one (08-05-2013)“…It is widely acknowledged that new regimens are urgently needed for the treatment of tuberculosis. The primary endpoint in the Phase III trials is a composite…”
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Estimands for clinical endpoints in tuberculosis treatment randomized controlled trials: a retrospective application in a completed trial
Published in Current controlled trials in cardiovascular medicine (12-03-2024)“…Randomized trials for the treatment of tuberculosis (TB) rely on a composite primary outcome to capture unfavorable treatment responses. However, variability…”
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6
High-temperature deformation mechanisms in a polycrystalline nickel-base superalloy studied by neutron diffraction and electron microscopy
Published in Acta materialia (01-08-2014)“…To study the effect of γ′ precipitate size on the deformation behaviour of a polycrystalline nickel-based superalloy, model microstructures with a unimodal γ′…”
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A comparison of clinical development pathways to advance tuberculosis regimen development
Published in BMC infectious diseases (09-12-2022)“…Current tuberculosis (TB) regimen development pathways are slow and in urgent need of innovation. We investigated novel phase IIc and seamless phase II/III…”
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A systematic review of endpoint definitions in late phase pulmonary tuberculosis therapeutic trials
Published in Current controlled trials in cardiovascular medicine (03-08-2021)“…Safe, more efficacious treatments are needed to address the considerable morbidity and mortality associated with pulmonary tuberculosis (TB). However, the…”
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9
Functional connectivity in the developing brain: A longitudinal study from 4 to 9 months of age
Published in NeuroImage (Orlando, Fla.) (01-01-2014)“…We characterize the development of intrinsic connectivity networks (ICNs) from 4 to 9 months of age with resting state magnetic resonance imaging performed on…”
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Completion of isoniazid-rifapentine (3HP) for tuberculosis prevention among people living with HIV: Interim analysis of a hybrid type 3 effectiveness-implementation randomized trial
Published in PLoS medicine (01-12-2021)“…Scaling up shorter regimens for tuberculosis (TB) prevention such as once weekly isoniazid-rifapentine (3HP) taken for 3 months is a key priority for achieving…”
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Investigation of the efficacy of the short regimen for rifampicin-resistant TB from the STREAM trial
Published in BMC medicine (04-11-2020)“…The STREAM trial demonstrated that a 9-11-month "short" regimen had non-inferior efficacy and comparable safety to a 20+ month "long" regimen for the treatment…”
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Use of whole-genome sequencing to distinguish relapse from reinfection in a completed tuberculosis clinical trial
Published in BMC medicine (29-03-2017)“…RIFAQUIN was a tuberculosis chemotherapy trial in southern Africa including regimens with high-dose rifapentine with moxifloxacin. Here, the application of…”
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Cost minimization analysis of line probe assay for detection of multidrug-resistant tuberculosis in Arkhangelsk region of Russian Federation
Published in PloS one (29-01-2019)“…The development of new diagnostic tools allows for faster detection of both tuberculosis (TB) and multidrug-resistant (MDR) TB and should lead to reduced…”
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Principles for designing future regimens for multidrug-resistant tuberculosis
Published in Bulletin of the World Health Organization (01-01-2014)“…Fewer than 20% of patients with multidrug-resistant (MDR) tuberculosis are receiving treatment and there is an urgent need to scale up treatment programmes…”
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15
2MASS near-infrared photometry of symbiotic stars
Published in Monthly notices of the Royal Astronomical Society (11-04-2007)“…We present Two Micron All Sky Survey photometry for 216 symbiotic and possible symbiotic stars. This represents the most comprehensive near-infrared photometry…”
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Setting Tuberculosis Regimen Development on a Firm Foundation
Published in Clinical infectious diseases (01-07-2017)Get full text
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The effect of vascular changes on the photoplethysmographic signal at different hand elevations
Published in Physiological measurement (01-03-2015)“…In order to further understand the contribution of venous and arterial effects to the photoplethysmographic (PPG) signal, recordings were made from 20 healthy…”
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Molecular Bacterial Load Assay, a Culture-Free Biomarker for Rapid and Accurate Quantification of Sputum Mycobacterium tuberculosis Bacillary Load during Treatment
Published in Journal of Clinical Microbiology (01-11-2011)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Performance comparison of Yb:YAG ceramics and crystal gain material in a large-area, high-energy, high average-power diode-pumped laser
Published in Optics express (03-02-2020)“…We compare for the first time the influence of different Yb:YAG gain media on the performance of a large-area, high average-power laser system with an output…”
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The Impact of a Line Probe Assay Based Diagnostic Algorithm on Time to Treatment Initiation and Treatment Outcomes for Multidrug Resistant TB Patients in Arkhangelsk Region, Russia
Published in PloS one (07-04-2016)“…In the Arkhangelsk region of Northern Russia, multidrug-resistant (MDR) tuberculosis (TB) rates in new cases are amongst the highest in the world. In 2014,…”
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