Search Results - "Phillips, John P"

Dynamic Functional Connectivity in Pediatric Mild Traumatic Brain Injury by van der Horn, Harm J, Ling, Josef M, Wick, Tracey V, Dodd, Andrew B, Robertson-Benta, Cidney R, McQuaid, Jessica R, Zotev, Vadim, Vakhtin, Andrei A, Ryman, Sephira G, Cabral, Joana, Phillips, John P, Campbell, Richard A, Sapien, Robert E, Mayer, Andrew R

“…Resting-state fMRI can be used to identify recurrent oscillatory patterns of functional connectivity within the human brain, also known as dynamic brain…”
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Hydrogen peroxide scavenging rescues frataxin deficiency in a Drosophila model of Friedreich's ataxia by Anderson, Peter R, Kirby, Kim, Orr, William C, Hilliker, Arthur J, Phillips, John P

“…Friedreich's ataxia (FRDA) is a neurodegenerative disorder arising from a deficit of the mitochondrial iron chaperone, frataxin. Evidence primarily from yeast…”
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RNA Interference-Mediated Silencing of Sod2 in Drosophila Leads to Early Adult-Onset Mortality and Elevated Endogenous Oxidative Stress by Kirby, Kim, Hu, Jianguo, Hilliker, Arthur J., Phillips, John P.

“…Oxidative stress has been widely implicated as an important factor in the aging process. Because mitochondrial respiration is the principal source of reactive…”
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Instability of Superoxide Dismutase 1 of Drosophila in Mutants Deficient for Its Cognate Copper Chaperone by Kirby, Kim, Jensen, Laran T., Binnington, Janet, Hilliker, Arthur J., Ulloa, Janella, Culotta, Valeria C., Phillips, John P.

“…Copper,zinc superoxide dismutase (SOD1) in mammals is activated principally via a copper chaperone (CCS) and to a lesser degree by a CCS-independent pathway of…”
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Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons by Phillips, John P, Parkes, Tony L, Elia, Andrew J, Dickinson, Dale, Hilliker, Arthur J, Boulianne, Gabrielle L

“…Reactive oxygen (RO) has been identified as an important effector in ageing and lifespan determination. The specific cell types, however, in which oxidative…”
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Evolution of universal review and disclosure of MRI reports to research participants by Shoemaker, Jody M., Cole, Caitlin, Petree, Linda E., Helitzer, Deborah L., Holdsworth, Mark T., Gluck, John P., Phillips, John P.

“…Background Although incidental findings (IF) are commonly encountered in neuroimaging research, there is no consensus regarding what to do with them. Whether…”
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Prematurity Affects Cortical Maturation in Early Childhood by Phillips, John P., MD, Montague, Erica Q., PhD, Aragon, Miranda, Lowe, Jean R., PhD, Schrader, Ronald M., PhD, Ohls, Robin K., MD, Caprihan, Arvind, PhD

“…Abstract Cortical development in the first years of age for children with very low birth weight is not well characterized. We obtained high-resolution…”
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Stakeholder Opinions and Ethical Perspectives Support Complete Disclosure of Incidental Findings in MRI Research by Phillips, John P., Cole, Caitlin, Gluck, John P., Shoemaker, Jody M., Petree, Linda E., Helitzer, Deborah L., Schrader, Ronald M., Holdsworth, Mark T.

“…How far does a researcher's responsibility extend when an incidental finding is identified? Balancing pertinent ethical principles such as beneficence, respect…”
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Enhanced tethered-flight duration and locomotor activity by overexpression of the human gene SOD1 in Drosophila motorneurons by Petrosyan, Agavni, Hsieh, I-Hui, Phillips, John P, Saberi, Kourosh

“…Mutation of the human gene superoxide dismutase (hSOD1) is associated with the fatal neurodegenerative disease familial amyotrophic lateral sclerosis (Lou…”
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Transverse Myelitis in a Child With COVID-19 by Kaur, Harsheen, Mason, John Alan, Bajracharya, Manish, McGee, John, Gunderson, Matthew D., Hart, Blaine L., Dehority, Walter, Link, Nathaniel, Moore, Brian, Phillips, John P., Rogers, Danny

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Compartment-specific Protection of Iron-Sulfur Proteins by Superoxide Dismutase by Missirlis, Fanis, Hu, Jianguo, Kirby, Kim, Hilliker, Arthur J, Rouault, Tracey A, Phillips, John P

“…Iron and oxygen are essential but potentially toxic constituents of most organisms, and their transport is meticulously regulated both at the cellular and…”
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Anterior Cingulate and Frontal Lobe White Matter Spectroscopy in Early Childhood of Former Very LBW Premature Infants by Phillips, John P, Ruhl, David, Montague, Erica, Gasparovic, Charles, Caprihan, Arvind, Ohls, Robin K, Schrader, Ronald, Lowe, Jean R

“…Neurometabolic sequelae of children born at very LBW (VLBW) are not well characterized in early childhood. Proton magnetic resonance spectroscopy (1H-MRS) and…”
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Of Two Cytosolic Aconitases Expressed in Drosophila, Only One Functions as an Iron-regulatory Protein by Lind, Maria I., Missirlis, Fanis, Melefors, Öjar, Uhrigshardt, Helge, Kirby, Kim, Phillips, John P., Söderhäll, Kenneth, Rouault, Tracey A.

“…In mammalian cells, iron homeostasis is largely regulated by post-transcriptional control of gene expression through the binding of iron-regulatory proteins…”
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Parkinson’s disease cerebrovascular reactivity pattern: A feasibility study by van der Horn, Harm Jan, Vakhtin, Andrei A, Julio, Kayla, Nitschke, Stephanie, Shaff, Nicholas, Dodd, Andrew B, Erhardt, Erik, Phillips, John P, Pirio Richardson, Sarah, Deligtisch, Amanda, Stewart, Melanie, Suarez Cedeno, Gerson, Meles, Sanne K, Mayer, Andrew R, Ryman, Sephira G

“…A mounting body of research points to cerebrovascular dysfunction as a fundamental element in the pathophysiology of Parkinson’s disease (PD). In the current…”
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Prospective Study of Gray Matter Atrophy Following Pediatric Mild Traumatic Brain Injury by Mayer, Andrew R., Meier, Timothy B., Dodd, Andrew B., Stephenson, David D., Robertson-Benta, Cidney R., Ling, Josef M., Pabbathi Reddy, Sharvani, Zotev, Vadim, Vakamudi, Kishore, Campbell, Richard A., Sapien, Robert E., Erhardt, Erik B., Phillips, John P., Vakhtin, Andrei A.

“…The clinical and physiologic time course for recovery following pediatric mild traumatic brain injury (pmTBI) remains actively debated. The primary objective…”
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Multifaceted neural and vascular pathologies after pediatric mild traumatic brain injury by Mayer, Andrew R, Dodd, Andrew B, Robertson-Benta, Cidney R, Zotev, Vadim, Ryman, Sephira G, Meier, Timothy B, Campbell, Richard A, Phillips, John P, van der Horn, Harm J, Hogeveen, Jeremy, Tarawneh, Rawan, Sapien, Robert E

“…Dynamic changes in neurodevelopment and cognitive functioning occur during adolescence, including a switch from reactive to more proactive forms of cognitive…”
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Persistent alterations in cerebrovascular reactivity in response to hypercapnia following pediatric mild traumatic brain injury by Dodd, Andrew B, Lu, Hanzhang, Wertz, Christopher J, Ling, Josef M, Shaff, Nicholas A, Wasserott, Benjamin C, Meier, Timothy B, Park, Grace, Oglesbee, Scott J, Phillips, John P, Campbell, Richard A, Liu, Peiying, Mayer, Andrew R

“…Much attention has been paid to the effects of mild traumatic brain injury (mTBI) on cerebrovascular reactivity in adult populations, yet it remains…”
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Multicompartmental models and diffusion abnormalities in paediatric mild traumatic brain injury by Mayer, Andrew R, Ling, Josef M, Dodd, Andrew B, Stephenson, David D, Pabbathi Reddy, Sharvani, Robertson-Benta, Cidney R, Erhardt, Erik B, Harms, Robbert L, Meier, Timothy B, Vakhtin, Andrei A, Campbell, Richard A, Sapien, Robert E, Phillips, John P

“…The underlying pathophysiology of paediatric mild traumatic brain injury and the time-course for biological recovery remains widely debated, with clinical care…”
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Association of Positive MRI Findings and Clinical Outcomes in Sub-acute and Chronic Phases of Pediatric Mild Traumatic Brain Injury by Sicard, Veronik, Hergert, Danielle, Stephenson, David, Robertson-Benta, Cidney Rae, Reddy, Sharvani Pabbathi, Dodd, Andrew, Ling, Josef, Wertz, Christopher James, Pluto, Charles, Campbell, Richard, Phillips, John P., Sapien, Robert, Oglesbee, Scott, Yeates, Keith, Mayer, Andrew

“…This study aims to examine the rates of incidental findings (IF) and radiologic common data elements (rCDE), and to explore how these magnetic resonance…”
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Comparison of Methods for Classifying Persistent Post-Concussive Symptoms in Children by Mayer, Andrew R, Stephenson, David D, Dodd, Andrew B, Robertson-Benta, Cidney R, Pabbathi Reddy, Sharvani, Shaff, Nicholas A, Yeates, Keith Owen, van der Horn, Harm J, Wertz, Christopher J, Park, Grace, Oglesbee, Scott J, Bedrick, Edward J, Campbell, Richard A, Phillips, John P, Quinn, Davin K

“…Pediatric mild traumatic brain injury (pmTBI) has received increased public scrutiny over the past decade, especially regarding children who experience…”
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