Search Results - "Phillips, JT"

A Randomized, Placebo-Controlled Trial of Natalizumab for Relapsing Multiple Sclerosis by Polman, Chris H, O'Connor, Paul W, Havrdova, Eva, Hutchinson, Michael, Kappos, Ludwig, Miller, David H, Phillips, J. Theodore, Lublin, Fred D, Giovannoni, Gavin, Wajgt, Andrzej, Toal, Martin, Lynn, Frances, Panzara, Michael A, Sandrock, Alfred W

“…This placebo-controlled, randomized trial of patients with relapsing multiple sclerosis demonstrated benefits of natalizumab (an α 4 integrin antagonist) in…”
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Immune surveillance in multiple sclerosis patients treated with natalizumab by Stüve, Olaf, Marra, Christina M., Jerome, Keith R., Cook, Linda, Cravens, Petra D., Cepok, Sabine, Frohman, Elliot M., Phillips, J. Theodore, Arendt, Gabriele, Hemmer, Bernhard, Monson, Nancy L., Racke, Michael K.

“…Objective Our objective was to test whether natalizumab, an antibody against very late activating antigen (VLA)‐4, interferes with central nervous system…”
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Interferon beta-1b in secondary progressive MS: Results from a 3-year controlled study by Panitch, Hillel, Miller, Aaron, Paty, Donald, Weinshenker, Brian

“…To evaluate the efficacy and safety of interferon beta-1b (IFNbeta-1b) in subjects with secondary progressive multiple sclerosis (SPMS). This 3-year,…”
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The utility of MRI in suspected MS: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology by FROHMAN, E. M, GOODIN, D. S, KACHUCK, N. J, LEVIN, M. C, PHILLIPS, J. T, RACKE, M. K, RIVERA, V. M, STUART, W. H, CALABRESI, P. A, CORBOY, J. R, COYLE, P. K, FILIPPI, M, FRANK, J. A, GALETTA, S. L, GROSSMAN, R. I, HAWKER, K

“…Advancements in imaging technologies and newly evolving treatments offer the promise of more effective management strategies for MS. Until recently,…”
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P2-12-32: Association between Progranulin (GP88) Expression and Recurrence Risk for Breast Cancer Patients with Estrogen Receptor Positive Invasive Ductal Carcinoma by Serrero, G, Hawkins, DM, Ioffe, O, Bejarano, P, Phillips, JT, Head, JF, Elliott, RL, Godwin, AK, Weaver, J, Yue, B

“…Abstract Purpose: GP88 (progranulin) is a critical player of breast tumorigenesis for estrogen receptor positive (ER+) breast cancer. Pathological studies…”
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Gender effects on intramuscular interferon beta-1a in relapsing–remitting multiple sclerosis: analysis of 1406 patients by Rudick, RA, Kappos, L, Kinkel, R, Clanet, M, Phillips, JT, Herndon, RM, Sandrock, AW, Munschauer, FE

“…Background: We aimed to evaluate effects of gender on efficacy and safety of intramuscular (IM) interferon beta (IFNβ)-1a in patients with relapsing–remitting…”
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A clinical therapeutic trial of cyclosporine in myasthenia gravis by Tindall, R S, Phillips, J T, Rollins, J A, Wells, L, Hall, K

“…We randomly assigned 39 patients with steroid-dependent generalized myasthenia gravis to treatment with cyclosporine (5 mg/kg per body weight in divided doses)…”
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An open-label safety and drug interaction study of natalizumab (Antegren™) in combination with interferon-beta (Avonex®) in patients with multiple sclerosis by Vollmer, T L, Phillips, J T, Goodman, A D, Agius, M A, Libonati, M A, Giacchino, J L, Grundy, J S

“…In this open-label drug-interaction trial, we studied 38 patients with relapsing-remitting multiple sclerosis (MS) who received 3.0 or 6.0 mg/kg of natalizumab…”
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Disease modifying agent related skin reactions in multiple sclerosis: prevention, assessment, and management by Frohman, E M, Brannon, K, Alexander, Sherry, Sims, D, Phillips, J T, O'Leary, S, Hawker, K, Racke, M K

“…Background: The objective for this article is to highlight some of the adverse skin manifestations associated with injectable disease modifying therapy for…”
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Quantitative oculographic characterisation of internuclear ophthalmoparesis in multiple sclerosis: the versional dysconjugacy index Z score by Frohman, E M, Frohman, T C, O'Suilleabhain, P, Zhang, H, Hawker, K, Racke, M K, Frawley, W, Phillips, J T, Kramer, P D

“…Background: There is a poor correlation between multiple sclerosis disease activity, as measured by magnetic resonance imaging, and clinical disability…”
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A multicenter, open-label, phase II study of the immunogenicity and safety of a new prefilled syringe (liquid) formulation of avonex in patients with multiple sclerosis by Phillips, J.Theodore, Rice, George, Frohman, Elliot, Vande Gaer, Luc, Scott, Thomas, Haas, Judith, Eggenberger, Eric, Freedman, Mark S, Stuart, William, Cunha, Luis, Jacobs, Lawrence, Oger, Joel, Arnold, Douglas, Jock Murray, T, DiBiase, Mary, Jethwa, Vijay, Goelz, Susan

“…Background: A new liquid formulation of Avonex (interferon beta-1a [IFNβ-1a]) in a prefilled syringe has been developed to make administration of the drug…”
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Characterizing the mechanisms of progression in multiple sclerosis: evidence and new hypotheses for future directions by Frohman, E M, Filippi, M, Stuve, O, Waxman, S G, Corboy, J, Phillips, J T, Lucchinetti, C, Wilken, J, Karandikar, N, Hemmer, B, Monson, N, De Keyser, J, Hartung, H, Steinman, L, Oksenberg, J R, Cree, B A C, Hauser, S, Racke, M K

“…Major advancements have been achieved in our ability to diagnose multiple sclerosis (MS) and to commence treatment intervention with agents that can favorably…”
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The utility of MRI in suspected MS: report of the Therapeutics and technology assessment Subcommittee of the American Academy of Neurology by Frohman, EM, Goodin, DS, Calabresi, PA, Corboy, JR, Coyle, PK, Filippi, M, Frank, JA, Galetta, SL, Grossman, RI, Hawker, K, Kachuck, NJ, Levin, MC, Phillips, JT, Racke, MK, Rivera, VM, Stuart, WH

“…[...]the presence of two or more gadolinium (Gd)-enhancing lesions at baseline and the appearance of either new T2 lesions or new Gd enhancement on follow-up…”
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Preliminary results of a double-blind, randomized, placebo-controlled trial of cyclosporine in myasthenia gravis by Tindall, R S, Rollins, J A, Phillips, J T, Greenlee, R G, Wells, L, Belendiuk, G

“…We randomly assigned 20 patients with progressively worsening generalized myasthenia gravis of recent onset whose illness was not controlled by…”
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Prolactin Stimulates Proliferation of Cultured Human Keratinocytes by Girolomoni, Giampiero, Phillips, J Theodore, Bergstresser, Paul R

“…The effect of the pituitary hormone prolactin on in vitro proliferation of human keratinocytes has been studied. Cell proliferation was determined by [3H]…”
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Modification of acute experimental autoimmune encephalomyelitis in the Lewis rat by oral administration of type 1 interferons by Brod, S A, Scott, M, Burns, D K, Phillips, J T

“…The effect of orally administered type 1 interferons on the severity of acute experimental autoimmune encephalomyelitis (EAE), a T cell-mediated autoimmune…”
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Therapeutic considerations for disease progression in multiple sclerosis: evidence, experience, and future expectations by Frohman, Elliot M, Stüve, Olaf, Havrdova, Eva, Corboy, John, Achiron, Anat, Zivadinov, Robert, Sorensen, Per Soelberg, Phillips, J Theodore, Weinshenker, Brian, Hawker, Kathleen, Hartung, Hans-Peter, Steinman, Lawrence, Zamvil, Scott, Cree, Bruce A C, Hauser, Stephen, Weiner, Howard, Racke, Michael K, Filippi, Massimo

“…In the management of patients with multiple sclerosis (MS), providers are all faced with the highly formidable challenge of ascertaining whether, and to what…”
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Prolactin receptor expression by lymphoid tissues in normal and immunized rats by Koh, C Y, Phillips, J T

“…Prolactin receptor (PRLr) expression and distribution in thymus, spleen, bone marrow, lymph nodes, and peripheral blood lymphocytes from young adult Lewis rats…”
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Rethinking multiple sclerosis by Phillips, J

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High incidence of post-lumbar puncture headaches in patients with multiple sclerosis treated with natalizumab: role of intrathecal leukocytes by Stüve, Olaf, Cravens, Petra D, Singh, Mahendra P, Frohman, Elliot M, Phillips, J Theodore, Remington, Gina, Hu, Wei, Hemmer, Bernhard, Olek, Michael J, Monson, Nancy L, Racke, Michael K

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