Search Results - "Phillips, Douglas J"

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    Half-life extension using serum albumin-binding DARPin® domains by Steiner, Daniel, Merz, Frieder W, Sonderegger, Ivo, Gulotti-Georgieva, Maya, Villemagne, Denis, Phillips, Douglas J, Forrer, Patrik, Stumpp, Michael T, Zitt, Christof, Binz, H Kaspar

    Published in Protein engineering, design and selection (01-09-2017)
    “…Abstract A long systemic half-life is key for therapeutic proteins. To that end we have generated serum albumin-binding designed ankyrin repeat domains. These…”
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    Journal Article
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    DLX1008 (brolucizumab), a single-chain anti-VEGF-A antibody fragment with low picomolar affinity, leads to tumor involution in an in vivo model of Kaposi Sarcoma by Eason, Anthony B, Sin, Sang-Hoon, Shah, Mohsin, Yuan, Hong, Phillips, Douglas J, Droste, Miriam, Shamshiev, Abdijapar, Dittmer, Dirk P

    Published in PloS one (14-05-2020)
    “…Kaposi Sarcoma (KS) is among the most angiogenic cancers in humans and an AIDS-defining condition. KS-associated herpesvirus (KSHV) is necessary for KS…”
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    Journal Article
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    Design and characterization of MP0250, a tri-specific anti-HGF/anti-VEGF DARPin® drug candidate by Binz, H Kaspar, Bakker, Talitha R, Phillips, Douglas J, Cornelius, Andreas, Zitt, Christof, Göttler, Thomas, Sigrist, Gabriel, Fiedler, Ulrike, Ekawardhani, Savira, Dolado, Ignacio, Saliba, Johan Abram, Tresch, Gaby, Proba, Karl, Stumpp, Michael T

    Published in mAbs (17-11-2017)
    “…MP0250 is a multi-domain drug candidate currently being tested in clinical trials for the treatment of cancer. It comprises one anti-vascular endothelial…”
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    Journal Article
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    DLX1008 by Eason, Anthony B, Sin, Sang-Hoon, Shah, Mohsin, Yuan, Hong, Phillips, Douglas J, Droste, Miriam, Shamshiev, Abdijapar, Dittmer, Dirk P

    Published in PloS one (14-05-2020)
    “…Kaposi Sarcoma (KS) is among the most angiogenic cancers in humans and an AIDS-defining condition. KS-associated herpesvirus (KSHV) is necessary for KS…”
    Get full text
    Journal Article
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    Abstract 4: Antitumor activity of DLX1008, a single chain antibody fragment binding to VEGF-A, in in vivo preclinical models of Kaposi sarcoma and glioblastoma by Eason, Anthony B., Sin, Sang-Hoon, Szabó, Emese, Phillips, Douglas J., Droste, Miriam, Shamshiev, Abdijapar, Dittmer, Dirk P., Weller, Michael

    Published in Cancer research (Chicago, Ill.) (01-07-2018)
    “…Abstract Background: Angiogenesis mediated by vascular endothelial growth factor (VEGF) is a hallmark of several cancers. Efficacy of VEGF inhibitors could be…”
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    Journal Article
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    Use of a standard-addition bromide-selective electrode technique to determine bromide and trace its migration in peaches by Austin, Rodney K, Phillips, Douglas J

    Published in Journal of agricultural and food chemistry (01-11-1985)
    “…A bromide-selective electrode (BrSE), coupled with a standard-addition procedure, was successful in detecting known levels of bromide ion in peach (Prunus…”
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    Journal Article
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    The Multi-Hex Prototype Experiment by Phillips, D.J., Hyland, D.C., Collins, E.G., King, J.A.

    “…The authors describe the Multi-Hex Prototype Experiment (MHPE), which was developed to experimentally investigate the technologies associated with the active…”
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    Conference Proceeding
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    Design and characterization of MP0250, a tri-specific anti-HGF/anti-VEGF DARPin® drug candidate by Binz, H. Kaspar, Bakker, Talitha R., Phillips, Douglas J., Cornelius, Andreas, Zitt, Christof, Göttler, Thomas, Sigrist, Gabriel, Fiedler, Ulrike, Ekawardhani, Savira, Dolado, Ignacio, Saliba, Johan Abram, Tresch, Gaby, Proba, Karl, Stumpp, Michael T.

    Published in mAbs (17-11-2017)
    “…MP0250 is a multi-domain drug candidate currently being tested in clinical trials for the treatment of cancer. It comprises one anti-vascular endothelial…”
    Get full text
    Report
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    Volume, nuclear number, and aggressiveness of conidia of Monilinia fructicola produced on media of varied glucose concentrations at 15 and 25 C by Phillips, D.J, Margosan, D.A, Mackey, B.E

    Published in Phytopathology (01-04-1989)
    “…Conidia of two isolates of Monilinia fructicola were produced at 15 and 25 C on potato-dextrose agar made with 20, 150, or 300 g of glucose per liter. At 15 C…”
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    Journal Article
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    Effect of temperature and high sugar concentrations on spore size of Monilinia fructicola by Margosan, D.A, Phillips, D.J

    Published in Mycologia (01-03-1989)
    “…When Monilinia fructicola (Wint.) Honey, causal agent of brown rot of stone fruit, is grown at 15 C on potato dextrose agar (PDA) it produces larger spores…”
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    Journal Article
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    Robust decentralized control laws for the ACES structure by Collins, E.G., Phillips, D.J., Hyland, D.C.

    Published in IEEE control systems (01-04-1991)
    “…Control system design for the Active Control Technique Evaluation for Spacecraft (ACES) structure at NASA Marshall Space Flight Center is discussed. The…”
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    Magazine Article
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