Search Results - "Philips, Brian J."

Heparanase inhibition preserves the endothelial glycocalyx in lung grafts and improves lung preservation and transplant outcomes by Noda, Kentaro, Philips, Brian J., Snyder, Mark E., Phillippi, Julie A., Sullivan, Mara, Stolz, Donna B., Ren, Xi, Luketich, James D., Sanchez, Pablo G.

“…The endothelial glycocalyx (eGC) is considered a key regulator of several mechanisms that prevent vascular injury and disease. Degradation of this…”
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Human ex vivo lung perfusion: a novel model to study human lung diseases by Cárdenes, Nayra, Sembrat, John, Noda, Kentaro, Lovelace, Tyler, Álvarez, Diana, Bittar, Humberto E. Trejo, Philips, Brian J., Nouraie, Mehdi, Benos, Panayiotis V., Sánchez, Pablo G., Rojas, Mauricio

“…Experimental animal models to predict physiological responses to injury and stress in humans have inherent limitations. Therefore, the development of…”
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Differential expression of functional cannabinoid receptors in human bladder detrusor and urothelium by Tyagi, Vikas, Philips, Brian J, Su, Ruthie, Smaldone, Marc C, Erickson, Vickie L, Chancellor, Michael B, Yoshimura, Naoki, Tyagi, Pradeep

“…Although cannabinoid receptor expression has been demonstrated in human brain and other peripheral neuronal tissues, definitive expression of these receptors…”
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Estrogen Sulfotransferase Inhibits Adipocyte Differentiation by Wada, Taira, Ihunnah, Chibueze A, Gao, Jie, Chai, Xiaojuan, Zeng, Su, Philips, Brian J, Rubin, J. Peter, Marra, Kacey G, Xie, Wen

“…The estrogen sulfotransferase (EST) is a phase II drug-metabolizing enzyme known to catalyze the sulfoconjugation of estrogens. EST is highly expressed in the…”
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Multiplex Analysis of Urinary Cytokine Levels in Rat Model of Cyclophosphamide-induced Cystitis by Smaldone, Marc C, Vodovotz, Yoram, Tyagi, Vikas, Barclay, Derek, Philips, Brian J, Yoshimura, Naoki, Chancellor, Michael B, Tyagi, Pradeep

“…Objectives The urinary proteome is a potential easily accessible source of biomarkers for inflammatory bladder diseases, including interstitial cystitis. In…”
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Antioxidant effects of green tea and its polyphenols on bladder cells by Coyle, Christian H., Philips, Brian J., Morrisroe, Shelby N., Chancellor, Michael B., Yoshimura, Naoki

“…Genitourinary tract inflammation/ailments affect the quality of life and health of a large segment of society. In recent years, studies have demonstrated…”
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Expression analysis of human adipose-derived stem cells during in vitro differentiation to an adipocyte lineage by Satish, Latha, Krill-Burger, J Michael, Gallo, Phillip H, Etages, Shelley Des, Liu, Fang, Philips, Brian J, Ravuri, Sudheer, Marra, Kacey G, LaFramboise, William A, Kathju, Sandeep, Rubin, J Peter

“…Adipose tissue-derived stromal stem cells (ASCs) represent a promising regenerative resource for soft tissue reconstruction. Although autologous grafting of…”
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Induction of apoptosis in human bladder cancer cells by green tea catechins by Philips, Brian J., Coyle, Christian H., Morrisroe, Shelby N., Chancellor, Michael B., Yoshimura, Naoki

“…Cell culture and animal studies have demonstrated strong chemopreventative effects of green tea and its associated polyphenols in multiple cancers, though the…”
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Endothelial protection in lung grafts through heparanase inhibition during ex vivo lung perfusion in rats by Noda, Kentaro, Philips, Brian J, Atale, Neha, Sanchez, Pablo G.

“…We hypothesized that enhancing glycocalyx preservation would reduce endothelial damage in lung grafts during ex-vivo lung perfusion (EVLP) leading to better…”
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Cyclosporin A Administration During Ex Vivo Lung Perfusion Preserves Lung Grafts in Rat Transplant Model by Haam, Seokjin, Noda, Kentaro, Philips, Brian J., Harano, Takashi, Sanchez, Pablo G., Shigemura, Norihisa

“…BACKGROUND.Despite the benefits of ex vivo lung perfusion (EVLP) such as lung reconditioning, preservation, and evaluation before transplantation, deleterious…”
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Impact of triptolide during ex vivo lung perfusion on grafts after transplantation in a rat model by Burki, Sarah, Noda, Kentaro, Philips, Brian J., Velayutham, Murugesan, Shiva, Sruti, Sanchez, Pablo G., Kumar, Ajay, D'Cunha, Jonathan

“…Ex vivo lung perfusion creates a proinflammatory environment leading to deterioration in graft quality that may contribute to post-transplant graft…”
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Adipose-derived stems cells and their role in human cancer development, growth, progression, and metastasis: a systematic review by Freese, Kyle E, Kokai, Lauren, Edwards, Robert P, Philips, Brian J, Sheikh, M Aamir, Kelley, Joseph, Comerci, John, Marra, Kacey G, Rubin, J Peter, Linkov, Faina

“…Obesity is a well recognized risk factor for several types of cancers, many of which occur solely or disproportionately in women. Adipose tissue is a rich…”
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Triptolide-induced apoptosis in non-small cell lung cancer via a novel miR204-5p/Caveolin-1/Akt-mediated pathway by Philips, Brian J., Kumar, Ajay, Burki, Sarah, Ryan, John P., Noda, Kentaro, D’Cunha, Jonathan

“…Lung cancer is one of the most prevalent malignancies world-wide with non-small cell lung cancer (NSCLC) comprising nearly 80% of all cases. Unfortunately,…”
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Prevalence of Endogenous CD34+ Adipose Stem Cells Predicts Human Fat Graft Retention in a Xenograft Model by Philips, Brian J., Grahovac, Tara L., Valentin, Jolene E., Chung, Christopher W., Bliley, Jacqueline M., Pfeifer, Melanie E., Roy, Sohini B., Dreifuss, Stephanie, Kelmendi-Doko, Arta, Kling, Russell E., Ravuri, Sudheer K., Marra, Kacey G., Donnenberg, Vera S., Donnenberg, Albert D., Rubin, J. Peter

“…Fat grafting is a promising technique for soft-tissue augmentation, although graft retention is highly unpredictable and factors that affect graft survival…”
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Adipose stem cell-based soft tissue regeneration by Philips, Brian J, Marra, Kacey G, Rubin, J Peter

“…Since their isolation and characterization nearly a decade ago, adipose-derived stem cells (ASCs) have become one of the most popular adult stem cell…”
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Healing of grafted adipose tissue: Current clinical applications of adipose-derived stem cells for breast and face reconstruction by Philips, Brian J., Marra, Kacey G., Rubin, J. Peter

“…Since their isolation and characterization nearly a decade ago, adipose‐derived stem cells (ASCs) have become one of the most popular adult stem cell…”
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Keratin Gel Filler for Peripheral Nerve Repair in a Rodent Sciatic Nerve Injury Model by Lin, Yen-Chih, Ramadan, Mostafa, Van Dyke, Mark, Kokai, Lauren E., Philips, Brian J., Rubin, J. Peter, Marra, Kacey G.

“…Restoration with sufficient functional recovery after long-gap peripheral nerve damage remains a clinical challenge. In vitro, keratins, which are derived from…”
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DNA damage effects of a polyamide-CBI conjugate in SV40 virions by Philips, Brian J, Chang, Aileen Y, Dervan, Peter B, Beerman, Terry A

“…Polyamides are a class of synthetic molecules that exhibit high-affinity, sequence-specific reversible binding in the DNA minor groove but are incapable of…”
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Biodegradable silk catheters for the delivery of therapeutics across anatomical repair sites by Brown, Joseph E, Tozzi, Lorenzo, Schilling, Benjamin, Kelmendi-Doko, Arta, Truong, April B, Rodriguez, Maria J, Gil, Eun Seok, Sucsy, Robert, Valentin, Jolene E, Philips, Brian J, Marra, Kacey G, Rubin, J Peter, Kaplan, David L

“…Biodegradable silk catheters for the delivery of therapeutics are designed with a focus on creating porous gradients that can direct the release of molecules…”
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Spatially Controlled Delivery of Neurotrophic Factors in Silk Fibroin-Based Nerve Conduits for Peripheral Nerve Repair by LIN, Yen-Chih, RAMADAN, Mostafa, HRONIK-TUPAJ, Marie, KAPLAN, David L, PHILIPS, Brian J, SIVAK, Wesley, PETER RUBIN, J, MARRA, Kacey G

“…Restoration with sufficient functional recovery after long-gap peripheral nerve damage remains a clinical challenge. Silk has shown clinical promise for…”
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