Search Results - "Philippe Lalle"

Impact of hypoxia on the double-strand break repair after photon and carbon ion irradiation of radioresistant HNSCC cells by Wozny, Anne-Sophie, Alphonse, Gersende, Cassard, Audrey, Malésys, Céline, Louati, Safa, Beuve, Michael, Lalle, Philippe, Ardail, Dominique, Nakajima, Tetsuo, Rodriguez-Lafrasse, Claire

“…DNA double-strand breaks (DSBs) induced by photon irradiation are the most deleterious damage for cancer cells and their efficient repair may contribute to…”
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Definition of a Short Region of XPG Necessary for TFIIH Interaction and Stable Recruitment to Sites of UV Damage by Thorel, Fabrizio, Constantinou, Angelos, Dunand-Sauthier, Isabelle, Nouspikel, Thierry, Lalle, Philippe, Raams, Anja, Jaspers, Nicolaas G. J., Vermeulen, Wim, Shivji, Mahmud K. K., Wood, Richard D., Clarkson, Stuart G.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A Common Mutational Pattern in Cockayne Syndrome Patients from Xeroderma Pigmentosum Group G: Implications for a Second XPG Function by Nouspikel, Thierry, Lalle, Philippe, Leadon, Steven A., Cooper, Priscilla K., Clarkson, Stuart G.

“…Xeroderma pigmentosum (XP) patients have defects in nucleotide excision repair (NER), the versatile repair pathway that removes UV-induced damage and other…”
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Conserved Residues of Human XPG Protein Important for Nuclease Activity and Function in Nucleotide Excision Repair by Constantinou, A, Gunz, D, Evans, E, Lalle, P, Bates, P A, Wood, R D, Clarkson, S G

“…The human XPG endonuclease cuts on the 3′ side of a DNA lesion during nucleotide excision repair. Mutations in XPG can lead to the disorders xeroderma…”
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Nrh, a human homologue of Nr-13 associates with Bcl-Xs and is an inhibitor of apoptosis by AOUACHERIA, Abdel, ARNAUD, Estelle, VENET, Séverine, LALLE, Philippe, GOUY, Manolo, RIGAL, Dominique, GILLET, Germain

“…In search of human homologues of the anti-apoptotic protein Nr-13, we have characterized a human EST clone that potentially encodes a protein, which is the…”
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Differential pattern of HIF-1α expression in HNSCC cancer stem cells after carbon ion or photon irradiation: one molecular explanation of the oxygen effect by Wozny, Anne-Sophie, Lauret, Alexandra, Battiston-Montagne, Priscillia, Guy, Jean-Baptiste, Beuve, Michael, Cunha, Micaela, Saintigny, Yannick, Blond, Emilie, Magne, Nicolas, Lalle, Philippe, Ardail, Dominique, Alphonse, Gersende, Rodriguez-Lafrasse, Claire

“…Background: Head and neck squamous cell carcinoma (HNSCC) are resistant to standard treatments, partly due to cancer stem cells (CSCs) localised in hypoxic…”
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Differential pattern of HIF-1[alpha] expression in HNSCC cancer stem cells after carbon ion or photon irradiation: one molecular explanation of the oxygen effect by Wozny, Anne-sophie, Lauret, Alexandra, Battiston-montagne, Priscillia, Guy, Jean-baptiste, Beuve, Michael, Cunha, Micaela, Saintigny, Yannick, Blond, Emilie, Magne, Nicolas, Lalle, Philippe, Ardail, Dominique, Alphonse, Gersende, Rodriguez-lafrasse, Claire

“…Background:Head and neck squamous cell carcinoma (HNSCC) are resistant to standard treatments, partly due to cancer stem cells (CSCs) localised in hypoxic…”
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RETRACTED: A common mutational pattern in Cockayne syndrome patients from xeroderma pigmentosum group G: Implications for a second XPG function by Nouspikel, Thierry, Lalle, Philippe, Leadon, Steven A., Cooper, Priscilla K., Clarkson, Stuart G.

“…Xeroderma pigmentosum (XP) patients have defects in nucleotide excision repair (NER), the versatile repair pathway that removes UV-induced damage and other…”
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Quels usages d’un dispositif de formation continue en ligne à la pédagogie universitaire ? by Pascaline Delalande, Philippe Lalle, Luc Massou, Carole Nocera-Picand, Nathalie Younes

“…This article has two objectives : to explain the engineering and pedagogical design of an online continuous training system for academics, beginners or not, to…”
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Quels usages d’un dispositif de formation continue en ligne à la pédagogie universitaire ?: Le cas du MOOC « Se former pour enseigner dans le supérieur by Delalande, Pascaline, Lalle, Philippe, Massou, Luc, Nocera-Picand, Carole, Younes, Nathalie

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Oocytes and early embryos selectively express the survival factor BCL2L10 by Guillemin, Yannis, Lalle, Philippe, Gillet, Germain, Guerin, Jean-François, Hamamah, Samir, Aouacheria, Abdel

“…Apoptosis has been reported in oocytes and human preimplantation embryos both in vitro and in vivo. BCL-2 family proteins are likely to play a pivotal role in…”
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La formation initiale et continue des enseignants et des formateurs à distance : enjeux, usages et ressources by Albero, Brigitte, Cabassut, Richard, Delalande, Pascaline, Gettliffe, Nathalie, Gras, Benjamin, Guérin, Jérôme, Heiser, Laurent, Klein, Hélène Hoblingre, Lalle, Philippe, Marquet, Pascal, Massou, Luc, Nocera-Picand, Carole, Peraya, Daniel, Pierrot, Laetitia, Poellhuber, Bruno, Pogent, Frédéric, Potolia, Anthippi, Romero, Margarida, Roy, Normand, Trestini, Marc, Tretola, Jessyca, Younes, Nathalie, Zourou, Katerina

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Quels usages d’un dispositif de formation continue en ligne à la pédagogie universitaire ? by Delalande, Pascaline, Lalle, Philippe, Massou, Luc, Nocera-Picand, Carole, Younes, Nathalie

“…Cet article vise deux objectifs : expliciter les choix d’ingénierie et de conception pédagogique d’un dispositif de formation continue en ligne des…”
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Quels usages d’un dispositif de formation continue en ligne à la pédagogie universitaire ? Le cas du MOOC « Se former pour enseigner dans le supérieur by Delalande, Pascaline, Lalle, Philippe, Massou, Luc, Nocera-Picand, Carole, Younes, Nathalie

“…This article has two objectives : to explain the engineering and pedagogical design of an online continuous training system for academics, beginners or not, to…”
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The Founding Members of Xeroderma Pigmentosum Group G Produce XPG Protein with Severely Impaired Endonuclease Activity by Lalle, Philippe, Nouspikel, Thierry, Constantinou, Angelos, Thorel, Fabrizio, Clarkson, Stuart G.

“…Of the eight human genes implicated in xeroderma pigmentosum, defects in XPG produce some of the most clinically diverse symptoms. These range from mild…”
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Evidence for crucial electrostatic interactions between Bcl-2 homology domains BH3 and BH4 in the anti-apoptotic Nr-13 protein by Lalle, Philippe, Aouacheria, Abdel, Dumont-Miscopein, Agnès, Jambon, Martin, Venet, Séverine, Bobichon, Hélène, Colas, Pierre, Deléage, Gilbert, Geourjon, Christophe, Gillet, Germain

“…Nr-13 is an anti-apoptotic member of the Bcl-2 family previously shown to interact with Bax. The biological significance of this interaction was explored both…”
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Detection of allelic losses on 17q12-q21 chromosomal region in benign lesions and malignant tumors occurring in a familial context by Lalle, P, De Latour, M, Rio, P, Bignon, Y J

“…A predisposing gene (BRCA-1) for breast and ovarian cancer has been located on chromosomal region 17q12-21. According to Knudson's hypothesis if this gene is a…”
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Genomic stability and wild-type p53 function of lymphoblastoid cells with germ-line p53 mutation by Lalle, P, Moyret-Lalle, C, Wang, Q, Vialle, J M, Navarro, C, Bressac-de Paillerets, B, Magaud, J P, Ozturk, M

“…Increased cancer risk associated with germ-line p53 mutation was linked to a deficit in the ability to maintain genomic stability. Accordingly, normal…”
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Two germ-line mutations affecting the same nucleotide at codon 257 of p53 gene, a rare site for mutations by Mazoyer, S, Lalle, P, Moyret-Lalle, C, Marçais, C, Schraub, S, Frappaz, D, Sobol, H, Ozturk, M

“…Codon 257 of the p53 gene is an extremely rare target for somatic mutations (accounting for only two of 1600 published mutations). We report here two…”
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Modulating mitochondria-mediated apoptotic cell death through targeting of Bcl-2 family proteins by Aouacheria, Abdel, Cibiel, Agnès, Guillemin, Yannis, Gillet, Germain, Lalle, Philippe

“…Research demonstrated that the function of mitochondria extends well beyond that of being cell powerhouses and revealed that these organelles fulfil a dual…”
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