Search Results - "Philippe Fosse"
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Norepinephrine weaning in septic shock patients by closed loop control based on fuzzy logic
Published in American journal of respiratory and critical care medicine (01-01-2008)“…The rate of weaning of vasopressors drugs is usually an empirical choice made by the treating in critically ill patients. We applied fuzzy logic principles to…”
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2
Deciphering the complete mitochondrial genome and phylogeny of the extinct cave bear in the Paleolithic painted cave of Chauvet
Published in Proceedings of the National Academy of Sciences - PNAS (11-11-2008)“…Retrieving a large amount of genetic information from extinct species was demonstrated feasible, but complete mitochondrial genome sequences have only been…”
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The Preliminary Analysis of Cave Lion Cubs Panthera spelaea (Goldfuss, 1810) from the Permafrost of Siberia
Published in Quaternary (01-09-2021)“…A preliminary description is presented of the well-preserved frozen mummies of two cubs of the extinct cave lion Panthera spelaea (finds of 2017–2018,…”
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Does Catheter‐Associated Urinary Tract Infection Increase Mortality in Critically Ill Patients?
Published in Infection control and hospital epidemiology (01-12-2007)“…To produce an accurate estimate of the association between catheter-associated urinary tract infection (UTI) and intensive care unit (ICU) and hospital…”
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Flexible Nature and Specific Functions of the HIV-1 Nucleocapsid Protein
Published in Journal of molecular biology (22-07-2011)“…One salient feature of reverse transcription in retroviruses, notably in the human immunodeficiency virus type 1, is that it requires the homologous…”
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RNA Structural Requirements for Nucleocapsid Protein-Mediated Extended Dimer Formation
Published in Viruses (15-03-2022)“…Retroviruses package two copies of their genomic RNA (gRNA) as non-covalently linked dimers. Many studies suggest that the retroviral nucleocapsid protein (NC)…”
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Noninvasive Ventilation Improves Preoxygenation before Intubation of Hypoxic Patients
Published in American journal of respiratory and critical care medicine (15-07-2006)“…Critically ill patients are predisposed to oxyhemoglobin desaturation during intubation. To find out whether noninvasive ventilation (NIV), as a preoxygenation…”
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Single-molecule studies reveal reciprocating of WRN helicase core along ssDNA during DNA unwinding
Published in Scientific reports (07-03-2017)“…Werner syndrome is caused by mutations in the WRN gene encoding WRN helicase. A knowledge of WRN helicase’s DNA unwinding mechanism in vitro is helpful for…”
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Agreement between quantitative cultures of postintubation tracheal aspiration and plugged telescoping catheter, protected specimen brush, or BAL for the diagnosis of nosocomial pneumonia
Published in Chest (01-10-2006)“…The diagnosis of ventilator-associated pneumonia relies on protected specimen brush (PSB), BAL, and plugged telescoping catheter (PTC) procedures. In the…”
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Structural and Dynamical Impact of a Universal Fluorescent Nucleoside Analogue Inserted Into a DNA Duplex
Published in The journal of physical chemistry. B (21-12-2017)“…Recently, a 3-hydroxychromone based nucleoside 3HCnt has been developed as a highly environment-sensitive nucleoside surrogate to investigate protein–DNA…”
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Rationally Designed Peptides as Efficient Inhibitors of Nucleic Acid Chaperone Activity of HIV‑1 Nucleocapsid Protein
Published in Biochemistry (Easton) (31-07-2018)“…Due to its essential roles in the viral replication cycle and to its highly conserved sequence, the nucleocapsid protein (NCp7) of the human immunodeficiency…”
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Dynamics of linker residues modulate the nucleic acid binding properties of the HIV-1 nucleocapsid protein zinc fingers
Published in PloS one (16-07-2014)“…The HIV-1 nucleocapsid protein (NC) is a small basic protein containing two zinc fingers (ZF) separated by a short linker. It is involved in several steps of…”
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Insights into the mechanisms of RNA secondary structure destabilization by the HIV-1 nucleocapsid protein
Published in RNA (Cambridge) (01-04-2016)“…The mature HIV-1 nucleocapsid protein NCp7 (NC) plays a key role in reverse transcription facilitating the two obligatory strand transfers. Several properties…”
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The catalytic triad of rice NARROW LEAF1 involves H234
Published in Nature plants (01-05-2024)“…NARROW LEAF1 ( NAL1 ) exerts a multifaceted influence on leaf morphology and crop yield. Recent crystal study proposed that histidine 233 (H233) is part of the…”
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Identification of acylation products in SHAPE chemistry
Published in Bioorganic & medicinal chemistry letters (01-06-2017)“…[Display omitted] SHAPE chemistry (selective 2′-hydroxyl acylation analyzed by primer extension) has been developed to specifically target flexible nucleotides…”
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Ontogeny/growth of (sub)modern brown bear (Ursus arctos) skeleton: A guideline to appraise seasonality for cave bear (Ursus spelaeus) sites?
Published in Quaternary international (07-08-2014)“…If cave bear (Ursus spelaeus) sites are suspected to be occupied during winters (hibernation), studies clearly demonstrating seasons of cave occupation by this…”
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Differential diagnostic value of procalcitonin in surgical and medical patients with septic shock
Published in Critical care medicine (01-01-2006)“…OBJECTIVE:To assess whether different diagnostic and prognostic cutoff values of procalcitonin should be considered in surgical and in medical patients with…”
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Structural insights into the cTAR DNA recognition by the HIV-1 nucleocapsid protein: role of sugar deoxyriboses in the binding polarity of NC
Published in Nucleic acids research (01-05-2011)“…An essential step of the reverse transcription of the HIV-1 genome is the first strand transfer that requires the annealing of the TAR RNA hairpin to the cTAR…”
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Structural Insights into the HIV-1 Minus-strand Strong-stop DNA
Published in The Journal of biological chemistry (12-02-2016)“…An essential step of human immunodeficiency virus type 1 (HIV-1) reverse transcription is the first strand transfer that requires base pairing of the R region…”
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Intrinsic nucleic acid dynamics modulates HIV-1 nucleocapsid protein binding to its targets
Published in PloS one (20-06-2012)“…HIV-1 nucleocapsid protein (NC) is involved in the rearrangement of nucleic acids occurring in key steps of reverse transcription. The protein, through its two…”
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