Search Results - "Philippe, Cécile"
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A truncated anti-CRISPR protein prevents spacer acquisition but not interference
Published in Nature communications (19-05-2022)“…CRISPR-Cas systems in prokaryotic cells provide an adaptive immunity against invading nucleic acids. For example, phage infection leads to addition of new…”
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Solitary fibrous tumor of the breast: A rare entity
Published in The breast journal (01-02-2020)Get more information
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Approaching Complete Inhibition of P-Glycoprotein at the Human Blood–Brain Barrier: An (R)-[11C]Verapamil PET Study
Published in Journal of cerebral blood flow and metabolism (01-05-2015)“…As P-glycoprotein (Pgp) inhibition at the blood–brain barrier (BBB) after administration of a single dose of tariquidar is transient, we performed positron…”
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Evaluation of Hepatic Glucose and Palmitic Acid Metabolism in Rodents on High-Fat Diet Using Deuterium Metabolic Imaging
Published in Journal of magnetic resonance imaging (09-05-2024)“…One of the main features of several metabolic disorders is dysregulation of hepatic glucose and lipid metabolism. Deuterium metabolic imaging (DMI) allows for…”
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5
Phage-host interactions as a driver of population dynamics during wine fermentation: Betting on underdogs
Published in International journal of food microbiology (16-12-2022)“…Winemaking is a complex process in which numerous microorganisms, mainly yeasts and lactic acid bacteria (LAB), play important roles. After alcoholic…”
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Effect of Rifampicin on the Distribution of [11C]Erlotinib to the Liver, a Translational PET Study in Humans and in Mice
Published in Molecular pharmaceutics (01-10-2018)“…Organic anion-transporting polypeptides (OATPs) mediate the uptake of various drugs from blood into the liver in the basolateral membrane of hepatocytes…”
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Bacteriophage GC1, a Novel Tectivirus Infecting Gluconobacter Cerinus, an Acetic Acid Bacterium Associated with Wine-Making
Published in Viruses (16-01-2018)“…The phage GC1 is a novel member of the family isolated from a juice sample collected during dry white wine making. The bacteriophage infects , an acetic acid…”
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A Proof-of-Concept Study to Inhibit ABCG2- and ABCB1-Mediated Efflux Transport at the Human Blood-Brain Barrier
Published in Journal of Nuclear Medicine (01-04-2019)“…The adenosine triphosphate-binding cassette transporters P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) are 2 efflux transporters at the…”
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The never-ending battle between lactic acid bacteria and their phages
Published in FEMS microbiology reviews (01-07-2023)“…Abstract Over the past few decades, the interest in lactic acid bacteria (LAB) has been steadily growing. This is mainly due to their industrial use, their…”
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10
Phage Encounters Recorded in CRISPR Arrays in the Genus Oenococcus
Published in Viruses (01-01-2023)“…The genus comprises four recognized species, and members have been found in different types of beverages, including wine, kefir, cider and kombucha. In this…”
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Effect of P‐glycoprotein inhibition at the blood–brain barrier on brain distribution of (R)‐[11C]verapamil in elderly vs. young subjects
Published in British journal of clinical pharmacology (01-09-2017)“…Aims The efflux transporter P‐glycoprotein (ABCB1) acts at the blood–brain barrier (BBB) to restrict the distribution of many different drugs from blood to the…”
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Measurement of Hepatic ABCB1 and ABCG2 Transport Activity with [11C]Tariquidar and PET in Humans and Mice
Published in Molecular pharmaceutics (06-01-2020)“…P-Glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) in the canalicular membrane of hepatocytes mediate the biliary excretion of drugs and drug…”
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A survey of oenophages during wine making reveals a novel group with unusual genomic characteristics
Published in International journal of food microbiology (18-09-2017)“…Oenophages have so far been mostly isolated from red wines under malolactic fermentation (MLF), and correspond to temperate or ex-temperate phages of…”
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14
Dynamics of human serotonin synthesis differentially link to reward anticipation and feedback
Published in Molecular psychiatry (23-08-2024)“…Serotonin (5-HT) plays an essential role in reward processing, however, the possibilities to investigate 5-HT action in humans during emotional stimulation are…”
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Characterization of the First Virulent Phage Infecting Oenococcus oeni , the Queen of the Cellars
Published in Frontiers in microbiology (13-01-2021)“…There has been little exploration of how phages contribute to the diversity of the bacterial community associated with winemaking and may impact fermentations…”
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Novel Genus of Phages Infecting Streptococcus thermophilus: Genomic and Morphological Characterization
Published in Applied and environmental microbiology (17-06-2020)“…is a lactic acid bacterium commonly used for the manufacture of yogurt and specialty cheeses. Virulent phages represent a major risk for milk fermentation…”
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Influence of OATPs on Hepatic Disposition of Erlotinib Measured With Positron Emission Tomography
Published in Clinical pharmacology and therapeutics (01-07-2018)“…To assess the hepatic disposition of erlotinib, we performed positron emission tomography (PET) scans with [11C]erlotinib in healthy volunteers without and…”
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Simultaneous radiomethylation of [11C]harmine and [11C]DASB and kinetic modeling approach for serotonergic brain imaging in the same individual
Published in Scientific reports (28-02-2022)“…Simultaneous characterization of pathologies by multi-tracer positron emission tomography (PET) is among the most promising applications in nuclear medicine…”
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Fecal microbiota transplantation promotes reduction of antimicrobial resistance by strain replacement
Published in Science translational medicine (01-11-2023)“…Multidrug-resistant organism (MDRO) colonization is a fundamental challenge in antimicrobial resistance. Limited studies have shown that fecal microbiota…”
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A Comprehensive Review for the Surveillance of Human Pathogenic Microorganisms in Shellfish
Published in Microorganisms (Basel) (31-08-2023)“…Bivalve molluscan shellfish have been consumed for centuries. Being filter feeders, they may bioaccumulate some microorganisms present in coastal water, either…”
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