Search Results - "Philip, N."

The clinical pharmacology profile of the new antiepileptic drug perampanel: A novel noncompetitive AMPA receptor antagonist by Patsalos, Philip N.

“…Summary The clinical pharmacology profile of a drug critically determines its therapeutics, and this review summarizes the characteristics associated with the…”
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RGF1 controls root meristem size through ROS signalling by Yamada, Masashi, Han, Xinwei, Benfey, Philip N.

“…The stem cell niche and the size of the root meristem in plants are maintained by intercellular interactions and signalling networks involving a peptide…”
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Soil erosion and sediment dynamics in the Anthropocene: a review of human impacts during a period of rapid global environmental change by Owens, Philip N.

“…Purpose Humanity has been modifying the planet in a measurable way for thousands of years. Recently, this influence has been such that some feel we are in a…”
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Global and country-level estimates of human population at high altitude by Tremblay, Joshua C., Ainslie, Philip N.

“…Estimates of the global population of humans living at high altitude vary widely, and such data at the country level are unavailable. Herein, we use a…”
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The Coevolution of Galaxies and Supermassive Black Holes: Insights from Surveys of the Contemporary Universe by Heckman, Timothy M, Best, Philip N

“…We summarize what large surveys of the contemporary Universe have taught us about the physics and phenomenology of the processes that link the formation and…”
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Modulation of Insulin Resistance in Nonalcoholic Fatty Liver Disease by Khan, Reenam S., Bril, Fernando, Cusi, Kenneth, Newsome, Philip N.

“…Nonalcoholic fatty liver disease (NAFLD) has an estimated prevalence of 25% in the general population, and cirrhosis secondary to nonalcoholic steatohepatitis…”
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A concise review of non-alcoholic fatty liver disease by Than, Nwe Ni, Newsome, Philip N

“…Abstract Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome and the incidence of which is rising rapidly due to…”
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Lithium Isotope History of Cenozoic Seawater: Changes in Silicate Weathering and Reverse Weathering by Misra, Sambuddha, Froelich, Philip N.

“…Weathering of uplifted continental rocks consumes carbon dioxide and transports cations to the oceans, thereby playing a critical role in controlling both…”
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High-Resolution Expression Map of the Arabidopsis Root Reveals Alternative Splicing and lincRNA Regulation by Li, Song, Yamada, Masashi, Han, Xinwei, Ohler, Uwe, Benfey, Philip N.

“…The extent to which alternative splicing and long intergenic noncoding RNAs (lincRNAs) contribute to the specialized functions of cells within an organ is…”
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Regulation of plant root system architecture: implications for crop advancement by Rogers, Eric D, Benfey, Philip N

“…Graphical abstract…”
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Clinical pathophysiology of hypoxic ischemic brain injury after cardiac arrest: a "two-hit" model by Sekhon, Mypinder S, Ainslie, Philip N, Griesdale, Donald E

“…Hypoxic ischemic brain injury (HIBI) after cardiac arrest (CA) is a leading cause of mortality and long-term neurologic disability in survivors. The…”
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Therapeutic Drug Monitoring of Antiepileptic Drugs in Epilepsy: A 2018 Update by Patsalos, Philip N, Spencer, Edgar P, Berry, Dave J

“…Antiepileptic drugs (AEDs) are the mainstay of epilepsy treatment. Since 1989, 18 new AEDs have been licensed for clinical use and there are now 27 licensed…”
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Regulation of cerebral blood flow and metabolism during exercise by Smith, Kurt J., Ainslie, Philip N.

“…New Findings What is the topic of this review? The manuscript collectively combines the experimental observations from >100 publications focusing on the…”
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A Placebo-Controlled Trial of Subcutaneous Semaglutide in Nonalcoholic Steatohepatitis by Newsome, Philip N, Buchholtz, Kristine, Cusi, Kenneth, Linder, Martin, Okanoue, Takeshi, Ratziu, Vlad, Sanyal, Arun J, Sejling, Anne-Sophie, Harrison, Stephen A

“…Patients with nonalcoholic steatohepatitis were randomly assigned to receive subcutaneous semaglutide or placebo. The incidence of NASH resolution was…”
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Incretins (GLP-1 receptor agonists and dual/triple agonists) and the liver by Newsome, Philip N, Ambery, Phil

“…The principle pathological drivers of metabolic dysfunction-associated steatohepatitis (MASH) are obesity and associated insulin resistance, rendering them key…”
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Drug Interactions with the Newer Antiepileptic Drugs (AEDs)—Part 1: Pharmacokinetic and Pharmacodynamic Interactions Between AEDs by Patsalos, Philip N.

“…Since 1989 there has been an exponential introduction of new antiepileptic drugs (AEDs) into clinical practice and these include eslicarbazepine acetate,…”
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Transcriptional Regulation of ROS Controls Transition from Proliferation to Differentiation in the Root by Tsukagoshi, Hironaka, Busch, Wolfgang, Benfey, Philip N.

“…The balance between cellular proliferation and differentiation is a key aspect of development in multicellular organisms. Using high-resolution expression data…”
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“Anything that Causes Chaos”: The Organizational Behavior of Russia Today (RT) by Elswah, Mona, Howard, Philip N

“…Abstract RT (formerly, Russia Today) is one of the most important organizations in the global political economy of disinformation. It is the most richly…”
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Predicting dust extinction from the stellar mass of a galaxy by Garn, Timothy, Best, Philip N.

“…We investigate how the typical dust extinction of Hα luminosity from a star-forming galaxy depends upon star formation rate (SFR), metallicity and stellar mass…”
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Systemic amyloidosis by Wechalekar, Ashutosh D, Dr, Gillmore, Julian D, FRCP, Hawkins, Philip N, FMedSci

“…Summary Tissue deposition of protein fibrils causes a group of rare diseases called systemic amyloidoses. This Seminar focuses on changes in their…”
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