Search Results - "Philibert, Claude"
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The roles of P-glycoprotein and intracellular metabolism in the intestinal absorption of methadone: in vitro studies using the rat everted intestinal sac
Published in Fundamental & clinical pharmacology (01-08-1999)“…— Methadone is used as a treatment for opiate detoxification in methadone maintenance programs. Intra‐ and inter‐patient variations in methadone…”
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Journal Article Conference Proceeding -
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In vitro Intestinal Degradation and Absorption of Chondroitin Sulfate, a Glycosaminoglycan Drug
Published in Arzneimittel-Forschung (01-01-2004)“…Summary Chondroitin sulfate (CAS 24967-93-9, CS) is a natural polymer of a disaccharide consisting of glucuronic acid and N-acetyl glucosamine which is…”
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Journal Article -
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The metabolism of midazolam and comparison with other CYP enzyme substrates during intestinal absorption: in vitro studies with rat everted gut sacs
Published in Journal of pharmacy & pharmaceutical sciences (2007)“…The purpose of this study was to quantify the intestinal metabolism of midazolam, a CYP P450 substrate, usually used as a probe for the activity of the isoform…”
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Journal Article -
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Oral absorption of ampicillin: role of paracellular route vs. PepT1 transporter
Published in Fundamental & clinical pharmacology (01-04-2008)“…The β‐lactam antibiotic ampicillin has a relatively poor oral bioavailability in animals and man (30–40%), and its widespread agricultural use in livestock may…”
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Journal Article -
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Toxicité des métaux
Published in Revue française des laboratoires (01-05-2000)“…La toxicité des principaux métaux (Pb, Hg, Cd, As, Al, Li, Co, Cr, Cu, Ni, Se, V et Zn) est décrite en insistant sur leur action à long terme, la plupart…”
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Journal Article -
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In vivo Study of Percutaneous Absorption of 4-Chloroaniline Using Microdialysis in the Rat
Published in Arzneimittel-Forschung (01-11-2000)“…Summary The present work was undertaken to study the percutaneous absorption of 4-chloroaniline (parachloroaniline, PCPA, CAS 106-47-8), a chemical…”
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