Search Results - "Philbert, IP"

Simple Elimination of Background Fluorescence in Formalin-Fixed Human Brain Tissue for Immunofluorescence Microscopy by Sun, Yulong, Ip, Philbert, Chakrabartty, Avijit

“…Immunofluorescence is a common method used to visualize subcellular compartments and to determine the localization of specific proteins within a tissue sample…”
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347 Functional characterization of GUCY2C-TAC T cells for the treatment of colorectal cancer using preclinical models by Benatar, Tania, Nitya-Nootan, Thanyashanthi, Thakor, Gargi, Prosser, Suzanna L, Ip, Philbert, Lal, Prabha, Khan, Alima, Xu, Stacey X, Pirati, Sailaja, Bhemarasetty, Deepika, Helsen, Christopher W, Bader, Andreas G

“…BackgroundThe T cell antigen coupler (TAC) is a novel chimeric receptor that facilitates the redirection of T cells to tumor cells and activates T cells by…”
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Wild-type Cu/Zn superoxide dismutase stabilizes mutant variants by heterodimerization by Weichert, Anna, Besemer, Anna S, Liebl, Martina, Hellmann, Nadja, Koziollek-Drechsler, Ingrid, Ip, Philbert, Decker, Heinz, Robertson, Janice, Chakrabartty, Avijit, Behl, Christian, Clement, Albrecht M

“…Abstract Mutations in the gene encoding Cu/Zn superoxide dismutase (SOD1) are responsible for a subset of amyotrophic lateral sclerosis cases presumably by the…”
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118 Development of Claudin 18.2 TAC T cells for the treatment of gastric cancer by Helsen, Christopher, Benatar, Tania, Philbert, IP, Xu, Stacey, Shaver, Laura, Nitya-Nootan, Thanyashanthi, Bader, Andreas, Lal, Prabha

“…BackgroundThe T cell antigen coupler (TAC) is a novel, proprietary chimeric receptor that facilitates the re-direction of T cells to tumor cells and activates…”
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Quercitrin and quercetin 3-β-d-glucoside as chemical chaperones for the A4V SOD1 ALS-causing mutant by Ip, Philbert, Sharda, Priya Roy, Cunningham, Anna, Chakrabartty, Sumon, Pande, Vijay, Chakrabartty, Avijit

“…Abstract In many cases of familial amyotrophic lateral sclerosis (ALS), mutant forms of the Cu,Zn superoxide dismutase protein (SOD1) misfold and aggregate in…”
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ALS-Causing SOD1 Mutations Promote Production of Copper-Deficient Misfolded Species by Ip, Philbert, Mulligan, Vikram Khipple, Chakrabartty, Avijit

“…Point mutations scattered throughout the sequence of Cu,Zn superoxide dismutase (SOD1) cause a subset of amyotrophic lateral sclerosis (ALS) cases. SOD1 is a…”
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Simple Elimination of Background Fluorescence in Formalin-Fixed Human Brain Tissue for Immunofluorescence Microscopy by Sun, Yulong, Ip, Philbert, Chakrabartty, Avijit

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294 Preclinical studies of TAC01-CLDN18.2, an autologous claudin 18.2-directed TAC T cell therapy, in the treatment of gastric cancer by Wang, Ling, Xu, Stacey, Benatar, Tania, Prosser, Suzanna, Shaver, Laura, Randhawa, Ritu, Ip, Philbert, Lal, Prabha, Nitya-Nootan, Thanyashanthi, MacGregor, Heather, Sengupta, Sadhak, Helsen, Christopher, Bader, Andreas

“…BackgroundThe T cell antigen coupler (TAC) is a novel, proprietary chimeric receptor that facilitates the re-direction of T cells to tumor cells and activates…”
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Abstract 572: Pre-clinical evaluation of Claudin 18.2 TAC T cells for the treatment of gastric cancer by Benatar, Tania, Wang, Ling, Nitya-Nootan, Thanyashanthi, MacGregor, Heather, Prosser, Suzanna, Ip, Philbert, Lal, Prabha, Shaver, Laura, Sengupta, Sadhak, Helsen, Christopher W., Bader, Andreas G.

“…Background: The T cell antigen coupler (TAC) is a novel, proprietary chimeric receptor that facilitates the re-direction of T cells to tumor cells and…”
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Abstract 3188: Patient-derived TAC01-HER2 TAC T cells produced in Cocoon® Platform is highly functional in models of solid tumors by Wang, Ling, Xu, Stacey X., Benatar, Tania, Randhawa, Ritu R., Ip, Philbert, Lal, Prabha, Nitya-Nootan, Thanyashanthi, Ravensbergen, Laura, MacGregor, Heather, Prosser, Suzy, Sengupta, Sadhak, Helsen, Christopher W., Bader, Andreas G.

“…Background: The T cell antigen coupler (TAC) is a novel, proprietary chimeric receptor that facilitates the re-direction of T cells to tumor cells and…”
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261 Evidence for durable anti-tumor responses by TAC-T cells in preclinical models of solid tumors by MacGregor, Heather, Moogk, Duane, Xu, Stacey, Hammill, Joanne, Ip, Philbert, Wang, Ling, Shetty, Swati, MacDonald, Kyle, Shaver, Laura, Pirati, Sailaja, Lal, Prabha, Helsen, Christopher, Bramson, Jonathan, Sengupta, Sadhak, Bader, Andreas

“…BackgroundT cell antigen coupler (TAC) is a chimeric receptor that redirects T cells (TAC-T) towards surface-expressed tumor antigens to create safe and…”
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The Misfolding Pathway of SOD1: Implications for Drug Design in ALS by Ip, Philbert Fung Wah

“…With the development of modern medicine, many diseases and maladies have been eradicated or rendered non-fatal. This has allowed human beings to live longer…”
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