Search Results - "Pharmacological reports"

Drug repurposing approach to fight COVID-19 by Singh, Thakur Uttam, Parida, Subhashree, Lingaraju, Madhu Cholenahalli, Kesavan, Manickam, Kumar, Dinesh, Singh, Raj Kumar

“…Currently, there are no treatment options available for the deadly contagious disease, coronavirus disease 2019 (COVID-19). Drug repurposing is a process of…”
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Therapeutic strategies for Alzheimer's disease in clinical trials by Godyń, Justyna, Jończyk, Jakub, Panek, Dawid, Malawska, Barbara

“…Alzheimer's disease (AD) is considered to be the most common cause of dementia and is an incurable, progressive neurodegenerative disorder. Current treatment…”
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The Nrf2-ARE signaling pathway: An update on its regulation and possible role in cancer prevention and treatment by Krajka-Kuźniak, Violetta, Paluszczak, Jarosław, Baer-Dubowska, Wanda

“…Nrf2 acts as a sensor of oxidative or electrophilic stress and prevents genome instability. The activation of Nrf2 signaling induces ARE-dependent expression…”
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Nanoparticles as drug delivery systems by Wilczewska, Agnieszka Z., Niemirowicz, Katarzyna, Markiewicz, Karolina H., Car, Halina

“…Controlled drug delivery systems (DDS) have several advantages compared to the traditional forms of drugs. A drug is transported to the place of action, hence,…”
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Efficacy of single and repeated administration of ketamine in unipolar and bipolar depression: a meta-analysis of randomized clinical trials by Kryst, Joanna, Kawalec, Paweł, Mitoraj, Alicja Mikrut, Pilc, Andrzej, Lasoń, Władysław, Brzostek, Tomasz

“…Due to unmet clinical needs for efficient drugs with a rapid onset of antidepressant effects, we aimed to evaluate the efficacy of single-dose ketamine in…”
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Overview of the possible role of vitamin C in management of COVID-19 by Abobaker, Anis, Alzwi, Aboubaker, Alraied, Alsalheen Hamed A

“…The mainstay of management of coronavirus disease 2019 (COVID-19) is mainly supportive as to date there is no effective antiviral treatment, apart from…”
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Understanding the role of ACE-2 receptor in pathogenesis of COVID-19 disease: a potential approach for therapeutic intervention by Shirbhate, Ekta, Pandey, Jaiprakash, Patel, Vijay K, Kamal, Mehnaz, Jawaid, Talha, Gorain, Bapi, Kesharwani, Prashant, Rajak, Harish

“…Angiotensin-converting enzyme (ACE) and its homologue, ACE2, are commonly allied with hypertension, renin-angiotensin-aldosterone system pathway, and other…”
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Beneficial roles of honey polyphenols against some human degenerative diseases: A review by Hossen, Md Sakib, Ali, Md Yousuf, Jahurul, M H A, Abdel-Daim, Mohamed M, Gan, Siew Hua, Khalil, Md Ibrahim

“…Honey contains many active constituents and antioxidants such as polyphenols. Polyphenols are phytochemicals, a generic term for the several thousand…”
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A review on antioxidant potential of bioactive heterocycle benzofuran: Natural and synthetic derivatives by Chand, Karam, Rajeshwari, Hiremathad, Asha, Singh, Mahak, Santos, M Amelia, Keri, Rangappa S

“…The majority of heterocycle compounds and typically common heterocycle fragments present in most pharmaceuticals currently marketed, alongside with their…”
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Chemotherapy-induced peripheral neuropathy: part 1-current state of knowledge and perspectives for pharmacotherapy by Sałat, Kinga

“…Despite the increasing knowledge of the etiology of neuropathic pain, this type of chronic pain is resistant to available analgesics in approximately 50% of…”
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Pharmacological properties of baicalin on liver diseases: a narrative review by Yang, Jin-Yu, Li, Min, Zhang, Cheng-Liang, Liu, Dong

“…Baicalin is the main active component of Scutellaria baicalensis, widely used in traditional Chinese medicine thanks to its various pharmacological effects,…”
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Cepharanthine: a review of the antiviral potential of a Japanese-approved alopecia drug in COVID-19 by Rogosnitzky, Moshe, Okediji, Paul, Koman, Igor

“…Cepharanthine (CEP) is a naturally occurring alkaloid derived from Stephania cepharantha Hayata and demonstrated to have unique anti-inflammatory,…”
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Oxidative stress as an etiological factor and a potential treatment target of psychiatric disorders. Part 2. Depression, anxiety, schizophrenia and autism by Smaga, Irena, Niedzielska, Ewa, Gawlik, Maciej, Moniczewski, Andrzej, Krzek, Jan, Przegaliński, Edmund, Pera, Joanna, Filip, Małgorzata

“…The pathophysiology of psychiatric diseases, including depression, anxiety, schizophrenia and autism, is far from being fully elucidated. In recent years, a…”
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Chemotherapy-induced peripheral neuropathy-part 2: focus on the prevention of oxaliplatin-induced neurotoxicity by Sałat, Kinga

“…Chemotherapy-induced peripheral neuropathy (CIPN) is regarded as one of the most common dose-limiting adverse effects of several chemotherapeutic agents, such…”
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Crocin protects cardiomyocytes against LPS-Induced inflammation by Baradaran Rahim, Vafa, Khammar, Mohammad Taghi, Rakhshandeh, Hassan, Samzadeh-Kermani, Alireza, Hosseini, Azar, Askari, Vahid Reza

“…Sepsis causes organ dysfunctions via elevation of oxidative stress and inflammation. Lipopolysaccharide (LPS) is the major surface molecule of most…”
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Caffeic acid improves locomotor activity and lessens inflammatory burden in a mouse model of rotenone-induced nigral neurodegeneration: Relevance to Parkinson's disease therapy by Zaitone, Sawsan A, Ahmed, Eman, Elsherbiny, Nehal M, Mehanna, Eman T, El-Kherbetawy, Mohammed K, ElSayed, Mohamed H, Alshareef, Duha M, Moustafa, Yasser M

“…Caffeic acid phenethyl ester is found in honey bee propolis. It has immunomodulatory, anti-inflammatory and anti-cancer properties. Rotenone is a pesticide…”
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Berberine and neurodegeneration: A review of literature by Ahmed, Touqeer, Gilani, Anwar-Ul-Hassan, Abdollahi, Mohammad, Daglia, Maria, Nabavi, Seyed Fazel, Nabavi, Seyed Mohammad

“…The excessive production of reactive oxygen species in nervous tissues is considered one of the major risk factors of neurodegenerative diseases. During the…”
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In-hospital use of statins is associated with a reduced risk of mortality in coronavirus-2019 (COVID-19): systematic review and meta-analysis by Permana, Hikmat, Huang, Ian, Purwiga, Aga, Kusumawardhani, Nuraini Yasmin, Sihite, Teddy Arnold, Martanto, Erwan, Wisaksana, Rudi, Soetedjo, Nanny Natalia M

“…The idea of treating COVID-19 with statins is biologically plausible, although it is still controversial. The systematic review and meta-analysis aimed to…”
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Anti-inflammatory and ameliorative effects of gallic acid on fluoxetine-induced oxidative stress and liver damage in rats by Karimi-Khouzani, Omid, Heidarian, Esfandiar, Amini, Sayed Asadollah

“…Fluoxetine-induced liver damage is a cause of chronic liver disease. In the present study the hepatoprotective effects of gallic acid against…”
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Recent review of COVID-19 management: diagnosis, treatment and vaccination by Chavda, Vivek P, Vuppu, Suneetha, Mishra, Toshika, Kamaraj, Sathvika, Patel, Aayushi B, Sharma, Nikita, Chen, Zhe-Sheng

“…The idiopathic Coronavirus disease 2019 (COVID-19) pandemic outbreak caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has reached…”
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