Search Results - "Pharmaceutical biology"

Coptidis Rhizoma: a comprehensive review of its traditional uses, botany, phytochemistry, pharmacology and toxicology by Wang, Jin, Wang, Lin, Lou, Guan-Hua, Zeng, Hai-Rong, Hu, Ju, Huang, Qin-Wan, Peng, Wei, Yang, Xiang-Bo

“…Context: Coptidis rhizome (CR), also known as Huanglian in Chinese, is the rhizome of Coptis chinensis Franch., C. deltoidea C.Y. Cheng et Hsiao, or C. teeta…”
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A comprehensive review on phytochemistry, pharmacology, and flavonoid biosynthesis of Scutellaria baicalensis by Wang, Zi-Long, Wang, Shuang, Kuang, Yi, Hu, Zhi-Min, Qiao, Xue, Ye, Min

“…Context: Scutellaria baicalensis Georgi (Lamiaceae) is a popular medicinal plant. Its roots are used as the famous traditional Chinese medicine Huang-Qin,…”
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The anti-inflammatory activity of licorice, a widely used Chinese herb by Yang, Rui, Yuan, Bo-Chuan, Ma, Yong-Sheng, Zhou, Shan, Liu, Ying

“…Context: Increasing incidence and impact of inflammatory diseases have encouraged the search of new pharmacological strategies to face them. Licorice has been…”
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Therapeutic potential of naringin: an overview by Chen, Rui, Qi, Qiao-Ling, Wang, Meng-Ting, Li, Qi-Yan

“…Context: Naringin is a natural flavanone glycoside that is found in the Chinese herbal medicines and citrus fruits. Studies have demonstrated that naringin…”
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A review of anti-inflammatory, antioxidant, and immunomodulatory effects of Allium cepa and its main constituents by Marefati, Narges, Ghorani, Vahideh, Shakeri, Farzaneh, Boskabady, Marzie, Kianian, Farzaneh, Rezaee, Ramin, Boskabady, Mohammad Hosein

“…Allium cepa L. (Liliaceae), known as onion, is consumed throughout the world. Onion and its derivatives including saponins, aglycones, quercetin, cepaenes,…”
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A systematic review of the active saikosaponins and extracts isolated from Radix Bupleuri and their applications by Yuan, Bochuan, Yang, Rui, Ma, Yongsheng, Zhou, Shan, Zhang, Xiaodong, Liu, Ying

“…Context: Radix Bupleuri has been used in traditional Chinese medicine for over 2000 years with functions of relieving exterior syndrome, clearing heat,…”
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Britanin relieves ferroptosis-mediated myocardial ischaemia/reperfusion damage by upregulating GPX4 through activation of AMPK/GSK3β/Nrf2 signalling by Lu, Haoyang, Xiao, Hui, Dai, Manyu, Xue, Yangcheng, Zhao, Ren

“…Ferroptosis was described as an important contributor to the myocardial ischaemia/reperfusion (MIR) injury, and britanin (Bri) was reported to exert antitumor…”
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Red ginseng polysaccharide exhibits anticancer activity through GPX4 downregulation-induced ferroptosis by Zhai, Feng-guo, Liang, Qi-chao, Wu, Yi-yan, Liu, Jia-qi, Liu, Jia-wei

“…Red ginseng polysaccharide (RGP) is an active component of the widely used medicinal plant Panax ginseng C. A. Meyer (Araliaceae), which has displayed…”
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Baicalin regulates macrophages polarization and alleviates myocardial ischaemia/reperfusion injury via inhibiting JAK/STAT pathway by Xu, Ming, Li, XiaoYong, Song, Laichun

“…Baicalin is an active compound which demonstrates cardioprotection effects against myocardial ischaemia/reperfusion injury (MI/RI). To investigate how baicalin…”
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Possible therapeutic effects of Nigella sativa and its thymoquinone on COVID-19 by Khazdair, Mohammad Reza, Ghafari, Shoukouh, Sadeghi, Mahmood

“…COVID-19 is a novel coronavirus that causes a severe infection in the respiratory system. Nigella sativa L. (Ranunculaceae) is an annual flowering plant used…”
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Ferulic acid alleviates alveolar epithelial barrier dysfunction in sepsis-induced acute lung injury by activating the Nrf2/HO-1 pathway and inhibiting ferroptosis by Tang, Xianming, Liu, Jiqiang, Yao, Shuo, Zheng, Jianfei, Gong, Xun, Xiao, Bing

“…Ferulic acid (FA) has antioxidative and anti-inflammatory effects, and is a promising drug to treat sepsis. To study the therapeutic effect of FA in…”
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Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway by Feng, Zhuo, Wang, Changyuan, Jin, Yue, Meng, Qiang, Wu, Jingjing, Sun, Huijun

“…The effect of kaempferol, a regulator of oestrogen receptors, on atherosclerosis (AS) and the underlying mechanism is elusive. To explore the effect and…”
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Soy isoflavones exert beneficial effects on letrozole-induced rat polycystic ovary syndrome (PCOS) model through anti-androgenic mechanism by Rajan, Ravi Kumar, M., Siva Selva Kumar, Balaji, Bhaskar

“…Context: Soy is the main source of phytoestrogens, which has long been used as traditional food. One major subtype of phytoestrogens includes isoflavones and…”
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GABA and l-theanine mixture decreases sleep latency and improves NREM sleep by Kim, Suhyeon, Jo, Kyungae, Hong, Ki-Bae, Han, Sung Hee, Suh, Hyung Joo

“…Context: γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter and it is well established that activation of GABA A receptors favours sleep…”
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Kaempferol suppresses acetaminophen-induced liver damage by upregulation/activation of SIRT1 by BinMowyna, Mona Nasser, AlFaris, Nora Abdullah

“…Kaempferol, a flavonoid glycoside, has many hepatoprotective effects in several animals due to its antioxidant potential. This study evaluated the…”
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Anti-inflammatory activity of clove (Eugenia caryophyllata) essential oil in human dermal fibroblasts by Han, Xuesheng, Parker, Tory L.

“…Context: Clove (Eugenia caryophyllata Thunb. [Myrtaceae]) essential oil (CEO) has been shown to possess antimicrobial, antifungal, antiviral, antioxidant,…”
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β-Sitosterol modulates macrophage polarization and attenuates rheumatoid inflammation in mice by Liu, Rui, Hao, Donglin, Xu, Wenya, Li, Jinjin, Li, Xiaoru, Shen, Dong, Sheng, Kang, Zhao, Lin, Xu, Weiwei, Gao, Zhongen, Zhao, Xu, Liu, Qiuhong, Zhang, Yiting

“…Context: β-Sitosterol (BS), the primary constituent of plants and vegetables, exhibits multiple biological effects. Objective: This study explores its effect…”
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Advances in phytochemical and modern pharmacological research of Rhizoma Corydalis by Tian, Bing, Tian, Ming, Huang, Shu-Ming

“…Rhizoma Corydalis (RC) is the dried tubers of Corydalis yanhusuo (Y. H. Chou and Chun C. Hsu) W. T. Wang ex Z. Y. Su and C. Y. Wu (Papaveraceae)…”
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Berberine regulates the Notch1/PTEN/PI3K/AKT/mTOR pathway and acts synergistically with 17-AAG and SAHA in SW480 colon cancer cells by Li, Ge, Zhang, Chuang, Liang, Wei, Zhang, Yanbing, Shen, Yunheng, Tian, Xinhui

“…Berberine (BBR) is used to treat diarrhoea and gastroenteritis in the clinic. It was found to have anticolon cancer effects. To study the anticolon cancer…”
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Traditional uses, phytochemistry and pharmacology of Ficus carica: a review by Badgujar, Shamkant B, Patel, Vainav V, Bandivdekar, Atmaram H, Mahajan, Raghunath T

“…Ficus carica Linn (Moraceae) has been used in traditional medicine for a wide range of ailments related to digestive, endocrine, reproductive, and respiratory…”
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