The Beta Subunit of the Interleukin-2 Receptor Mediates Interleukin-2 Induction of Anti-CD3 Redirected Cytotoxic Capability in Large Granular Lymphocytes

The interleukin 2 (IL 2) receptor was studied in three cases of large granular lymphocyte (LGL) lymphocytosis. All cases were nonreactive with anti-Tac monoclonal antibody (MoAb; recognizing the p55 alpha subunit of the IL 2 receptor). Sodium dodecyl sulfate (SDS)/polyacrylamide gel electrophoretic...

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Bibliographic Details

Published in:	Blood Vol. 71; no. 3; pp. 825 - 828
Main Authors:	Colamonici, O.R., Quinones, R., Rosolen, A., J.B., Trepel, Sausville, E., Phares, J.C., Gress, R., Poplack, D., Weber, J., Schechter, G.P., Neckers, L.M.
Format:	Journal Article
Language:	English
Published:	Washington, DC Elsevier Inc 01-03-1988 The Americain Society of Hematology
Subjects:	Antigens, Surface - immunology Biological and medical sciences Cytotoxicity, Immunologic Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Interleukin-2 - pharmacology Lymphocytes - immunology Lymphocytes - metabolism Receptors, Immunologic - metabolism Receptors, Immunologic - physiology Receptors, Interleukin-2 Recombinant Proteins
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