Search Results - "Phansopa, Chatchawal"
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Lateral Gene Transfer Acts As an Evolutionary Shortcut to Efficient C4 Biochemistry
Published in Molecular biology and evolution (01-11-2020)“…Abstract The adaptation of proteins for novel functions often requires changes in their kinetics via amino acid replacement. This process can require multiple…”
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Characterization of Porphyromonas gingivalis sialidase and disruption of its role in host-pathogen interactions
Published in Microbiology (Society for General Microbiology) (01-11-2019)“…Key to onset and progression of periodontitis is a complex relationship between oral bacteria and the host. The organisms most associated with severe…”
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Evidence for a carbohydrate-binding module (CBM) of Tannerella forsythia NanH sialidase, key to interactions at the host-pathogen interface
Published in Biochemical journal (30-03-2018)“…Bacterial sialidases cleave terminal sialic acid from a variety of host glycoproteins, and contribute to survival and growth of many human-dwelling bacterial…”
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Structural and functional characterization of NanU, a novel high-affinity sialic acid-inducible binding protein of oral and gut-dwelling Bacteroidetes species
Published in Biochemical journal (15-03-2014)“…Many human-dwelling bacteria acquire sialic acid for growth or surface display. We identified previously a sialic acid utilization operon in Tannerella…”
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A bacterial glycan core linked to surface (S)-layer proteins modulates host immunity through Th17 suppression
Published in Mucosal immunology (01-03-2013)“…Tannerella forsythia is a pathogen implicated in periodontitis, an inflammatory disease of the tooth-supporting tissues often leading to tooth loss. This key…”
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Characterization of a sialate-O-acetylesterase (NanS) from the oral pathogen Tannerella forsythia that enhances sialic acid release by NanH, its cognate sialidase
Published in Biochemical journal (01-12-2015)“…Tannerella forsythia, a Gram-negative member of the Bacteroidetes has evolved to harvest and utilize sialic acid. The most common sialic acid in humans is a…”
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The Virulence Factor PEB4 (Cj0596) and the Periplasmic Protein Cj1289 Are Two Structurally Related SurA-like Chaperones in the Human Pathogen Campylobacter jejuni
Published in The Journal of biological chemistry (17-06-2011)“…The PEB4 protein is an antigenic virulence factor implicated in host cell adhesion, invasion, and colonization in the food-borne pathogen Campylobacter jejuni…”
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Physiological adaptations of key oral bacteria
Published in Advances in microbial physiology (2014)“…Oral colonising bacteria are highly adapted to the various environmental niches harboured within the mouth, whether that means while contributing to one of the…”
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Beta-hexosaminidase activity of the oral pathogen Tannerella forsythia influences biofilm formation on glycoprotein substrates
Published in FEMS immunology and medical microbiology (01-06-2012)“…Abstract Tannerella forsythia is an important pathogen in periodontal disease. Previously, we showed that its sialidase activity is key to utilization of…”
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