Search Results - "Phan, Timothy S"

Misinterpretation of the Determinants of Elevated Forward Wave Amplitude Inflates the Role of the Proximal Aorta by Phan, Timothy S., Li, John K‐J., Segers, Patrick, Chirinos, Julio A.

“…Background The hemodynamic basis for increased pulse pressure (PP) with aging remains controversial. The classic paradigm attributes a predominant role to…”
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Visualization and Analysis of Multidimensional Cardiovascular Magnetic Resonance Imaging: Challenges and Opportunities by Axel, Leon, Phan, Timothy S., Metaxas, Dimitris N.

“…Recent advances in magnetic resonance imaging are enabling the efficient creation of high-dimensional, multiparametric images, containing a wealth of potential…”
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Aging is Associated With an Earlier Arrival of Reflected Waves Without a Distal Shift in Reflection Sites by Phan, Timothy S., Li, John K.‐J., Segers, Patrick, Reddy‐Koppula, Maheswara, Akers, Scott R., Kuna, Samuel T., Gislason, Thorarinn, Pack, Allan I., Chirinos, Julio A.

“…Background Despite pronounced increases in central pulse wave velocity (PWV) with aging, reflected wave transit time (RWTT), traditionally defined as the…”
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Beta‐Blocker Use Is Associated With Impaired Left Atrial Function in Hypertension by Sardana, Mayank, Syed, Amer Ahmed, Hashmath, Zeba, Phan, Timothy S., Koppula, Maheswara R., Kewan, Uzma, Ahmed, Zoubair, Chandamuri, Ravikantha, Varakantam, Swapna, Shah, Ejaz, Gorz, Ryan, Akers, Scott R., Chirinos, Julio A.

“…Background Impaired left atrial (LA) mechanical function is present in hypertension and likely contributes to various complications, including atrial…”
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Replicating human expertise of mechanical ventilation waveform analysis in detecting patient-ventilator cycling asynchrony using machine learning by Gholami, Behnood, Phan, Timothy S., Haddad, Wassim M., Cason, Andrew, Mullis, Jerry, Price, Levi, Bailey, James M.

“…— Acute respiratory failure is one of the most common problems encountered in intensive care units (ICU) and mechanical ventilation is the mainstay of…”
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Effects of organic and inorganic nitrate on aortic and carotid haemodynamics in heart failure with preserved ejection fraction by Chirinos, Julio A., Londono‐Hoyos, Francisco, Zamani, Payman, Beraun, Melissa, Haines, Philip, Vasim, Izzah, Varakantam, Swapna, Phan, Timothy S., Cappola, Thomas P., Margulies, Kenneth B., Townsend, Raymond R., Segers, Patrick

“…Aims To assess the haemodynamic effects of organic vs. inorganic nitrate administration among patients with heart failure with preserved ejection fraction…”
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HEART-FEMORAL PULSE WAVE VELOCITY IS A STRONGER MARKER OF ARTERIAL AGING THAN CAROTID-FEMORAL PULSE WAVE VELOCITY by Phan, Timothy S, Syed, Amer Ahmed, Oldland, Harry Garrett, Sanchez, Nicolas, Hashmath, Zeba, Akers, Scott R, Chirinos, Julio A

“…After adjustment for sex, BMI, mean arterial pressure, and heart rate, age remained more explanatory of variance in hfPWV (R2=0.44) than cfPWV (R2=0.34)…”
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Validation of an automated system for detecting ineffective triggering asynchronies during mechanical ventilation: a retrospective study by Phan, Timothy S., Costa, Roberta, Haddad, Wassim M., Mullis, Jerry C., Price, Levi T., Cason, Andrew D., Bailey, James M., Gholami, Behnood

“…We compare the sensitivity and specificity of clinician visual waveform analysis against an automated system’s waveform analysis in detecting ineffective…”
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Late Systolic Myocardial Loading Is Associated With Left Atrial Dysfunction in Hypertension by Chirinos, Julio A, Phan, Timothy S, Syed, Amer A, Hashmath, Zeba, Oldland, Harry G, Koppula, Maheswara R, Tariq, Ali, Javaid, Khuzaima, Miller, Rachana, Varakantam, Swapna, Dunde, Anjaneyulu, Neetha, Vadde, Akers, Scott R

“…Late systolic load has been shown to cause diastolic dysfunction in animal models. Although the systolic loading sequence of the ventricular myocardium likely…”
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CARDIO-FEMORAL VASCULAR INDEX: A NEW MARKER OF ARTERIAL AGING by Phan, Timothy S, Oldland, Harry Garett, Javaid, Khuzaima, Kewan, Uzma, Vasim, Izzah, Varakantam, Swapna, Akers, Scott R, Chirinos, Julio A

“…After adjustment for sex, BMI, heart rate and mean arterial pressure, age remained more strongly explanatory of CAFI (R2=0.38) than CAVI (R2=0.28)…”
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DECREASED AORTIC INERTANCE IS INDEPENDENTLY ASSOCIATED WITH LEFT VENTRICULAR HYPERTROPHY: ROLE IN VENTRICULAR-ARTERIAL COUPLING by Phan, Timothy S, Hashmath, Zeba, Syed, Amer Ahmed, Vasim, Izzah, Kewan, Uzma, Varakantam, Swapna, Akers, Scott R, Chirinos, Julio A

“…Modeling/theoretical considerations indicate that independent of changes within the arterial wall, aortic dilation counters this favorable uncoupling during…”
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ACQUISITION OF TIME-RESOLVED BRACHIAL PRESSURE WAVEFORMS FROM CUFF-BASED PULSE VOLUME RECORDINGS by Phan, Timothy S, Dakka, Jumana, Syed, Amer Ahmed, Vasim, Izzah, Oldland, Harry G, Kewan, Uzma, Akers, Scott R, Chirinos, Julio A

“…Comparisons were made between PVR, PVRp and AT waveforms for (1) Form Factor (FF); (2) Systolic Pressure-Time Integral (SPTI); (3) Diastolic Pressure-Time…”
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EFFECT OF DIABETES MELLITUS ON PULSATILE ARTERIAL LOAD AND HEMODYNAMICS IN HFPEF by Chirinos, Julio A., Zamani, Payman, Hashmath, Zeba, Koppula, Maheshwara Reddy, Syed, Amer Ahmed, Bhattacharya, Priyanka, Chahwala, Jugal, Oldland, Harry G., Miller, Rachana, Kewan, Uzma, Varakantam, Swapna, Tariq, Ali, Phan, Timothy S., Akers, Scott

“…In multivariable models that adjusted for age, sex, race, body mass index, and mean arterial pressure, DM remained a significant independent predictor of…”
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Decreased aortic inertance increases susceptibility of late-systolic left ventricular ejection to arterial wave reflections by Phan, Timothy S, Li, John K.-J, Syed, Amer Ahmed, Oldland, Harry G, Kewan, Uzma, Akers, Scott R, Chirinos, Julio A

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Bilateral symmetry of brachial pulse waveform analysis in a clinical population by Dakka, Jumana, Phan, Timothy S, Vasim, Izzah, Varakantam, Swapna, Kewan, Uzma, Tariq, Ali, Oldland, Harry G, Syed, Amer Ahmed, Hashmath, Zeba, Akers, Scott R, Chirinos, Julio A

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OR-04 DECREASED AORTIC INERTANCE INCREASES SUSCEPTIBILITY OF LATE-SYSTOLIC LEFT VENTRICULAR EJECTION TO ARTERIAL WAVE REFLECTIONS by Phan, Timothy S., Li, John K.-J., Syed, Amer Ahmed, Oldland, Harry G., Kewan, Uzma, Akers, Scott R., Chirinos, Julio A.

“…Background: Left ventricular (LV) afterload patterns consisting of late-systolic loading has been linked to LV remodeling and fibrosis in a number of studies…”
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PO-26 BILATERAL SYMMETRY OF BRACHIAL PULSE WAVEFORM ANALYSIS IN A CLINICAL POPULATION by Dakka, Jumana, Phan, Timothy S., Vasim, Izzah, Varakantam, Swapna, Kewan, Uzma, Tariq, Ali, Oldland, Harry G., Syed, Amer Ahmed, Hashmath, Zeba, Akers, Scott R., Chirinos, Julio A.

“…Background: Pulse waveforms are modified as they propagate along the arterial tree. Small differences in the arterial pathways from the heart to the left and…”
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Reduced-order nonlinear arterial compliance parameter estimation under vasoactive states by Phan, Timothy S., Li, John K.-J

“…The arterial system is coupled with the heart, such that the pressure produced by the left ventricle of the heart is in tune to properties of the vasculature…”
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Abstract 13951: Circulating Inactive Matrix Gla-protein, Warfarin Use and Large Artery Stiffness in Heart Failure With Reduced Ejection Fraction by Chirinos, Julio A, Vassim, Izzah, Varakantam, Swapna, Phan, Timothy S, Syed, Amer Ahmed, Bhattacharya, Priyanka, Beraun, Melissa, Soto-Calderon, Haideliza, Akers, Scott R

“…Backgroundlarge artery stiffness increases pulsatile afterload to the LV and is strongly predictive of adverse outcomes in heart failure and reduced ejection…”
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Propagation of uncertainty and analysis of signal-to-noise in nonlinear compliance estimations of an arterial system model by Phan, Timothy S., Li, John K.-J

“…The arterial system dynamically loads the heart through changes in arterial compliance. The pressure-volume relation of arteries is known to be nonlinear, but…”
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