Search Results - "Phan, Tien"

Developing Bonded Potentials for a Coarse-Grained Model of Intrinsically Disordered Proteins by Rizuan, Azamat, Jovic, Nina, Phan, Tien M., Kim, Young C., Mittal, Jeetain

“…Recent advances in residue-level coarse-grained (CG) computational models have enabled molecular-level insights into biological condensates of intrinsically…”
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Wnt/β-catenin signaling promotes regeneration after adult zebrafish spinal cord injury by Strand, Nicholas S., Hoi, Kimberly K., Phan, Tien M.T., Ray, Catherine A., Berndt, Jason D., Moon, Randall T.

“…Unlike mammals, zebrafish can regenerate their injured spinal cord and regain control of caudal tissues. It was recently shown that Wnt/β-catenin signaling is…”
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Conformational entropy limits the transition from nucleation to elongation in amyloid aggregation by Phan, Tien M., Schmit, Jeremy D.

“…The formation of β-sheet-rich amyloid fibrils in Alzheimer’s disease and other neurodegenerative disorders is limited by a slow nucleation event. To understand…”
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Molecular insights into phase separation of HP1 isoforms using coarse-grained and atomistic simulations by Phan, Tien M., Kapoor, Utkarsh, Debelouchina, Galia T., Mittal, Jeetain

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Acetylation-Dependent Compaction of the Histone H4 Tail Ensemble by Dewing, Sophia M., Phan, Tien M., Kraft, Emma J., Mittal, Jeetain, Showalter, Scott A.

“…Acetylation of the histone H4 tail (H4Kac) has been established as a significant regulator of chromatin architecture and accessibility; however, the molecular…”
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Molecular interactions underlying the phase separation of HP1α: role of phosphorylation, ligand and nucleic acid binding by Her, Cheenou, Phan, Tien M, Jovic, Nina, Kapoor, Utkarsh, Ackermann, Bryce E, Rizuan, Azamat, Kim, Young C, Mittal, Jeetain, Debelouchina, Galia T

“…Heterochromatin protein 1α (HP1α) is a crucial element of chromatin organization. It has been proposed that HP1α functions through liquid-liquid phase…”
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Expression of PD-L1 and presence of CD8-positive T cells in pre-treatment specimens of locally advanced cervical cancer by Enwere, Emeka K, Kornaga, Elizabeth N, Dean, Michelle, Koulis, Theodora A, Phan, Tien, Kalantarian, Maria, Köbel, Martin, Ghatage, Prafull, Magliocco, Anthony M, Lees-Miller, Susan P, Doll, Corinne M

“…Several of the cancer immunotherapies under investigation or in clinical use target the programmed death-ligand 1/programmed death-1 (PD-L1/PD-1) signaling…”
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Interplay between charge distribution and DNA in shaping HP1 paralog phase separation and localization by Phan, Tien M, Kim, Young C, Debelouchina, Galia T, Mittal, Jeetain

“…The heterochromatin protein 1 (HP1) family is a crucial component of heterochromatin with diverse functions in gene regulation, cell cycle control, and cell…”
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Numerical approximations of stochastic delay differential equations with delayed impulses by Quan Tran, Ky, Trong Tien, Phan

“…This paper focuses on approximating stochastic delay differential equations with delayed impulses using Euler-Maruyama-type approximations. One key difference…”
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Beneficial and detrimental effects of non-specific binding during DNA hybridization by Phan, Tam T.M., Phan, Tien M., Schmit, Jeremy D.

“…DNA strands have to sample numerous states to find the alignment that maximizes Watson-Crick-Franklin base pairing. This process depends strongly on sequence,…”
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Dexamethasone-Induced Ocular Hypertension in Mice: Effects of Myocilin and Route of Administration by Patel, Gaurang C, Phan, Tien N, Maddineni, Prabhavathi, Kasetti, Ramesh B, Millar, J Cameron, Clark, Abbot F, Zode, Gulab S

“…Glucocorticoid (GC)-induced ocular hypertension (OHT) is a serious adverse effect of prolonged GC therapy that can lead to iatrogenic glaucoma and permanent…”
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Adaptive Visual Assistance System for Enhancing the Driver Awareness of Pedestrians by Frémont, Vincent, Phan, Minh-Tien, Thouvenin, Indira

“…In the past decade, Pedestrian Collision Warning Systems have been proposed to detect pedestrians and warn drivers of imminent collision. However, such systems…”
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Optimal Earthquake Intensity Measures for Probabilistic Seismic Demand Models of Base-Isolated Nuclear Power Plant Structures by Nguyen, Duy-Duan, Lee, Tae-Hyung, Phan, Van-Tien

“…The purpose of this study is to evaluate the optimal earthquake intensity measures (IMs) for probabilistic seismic demand models (PSDMs) of the base-isolated…”
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Expression of Mutant Myocilin Induces Abnormal Intracellular Accumulation of Selected Extracellular Matrix Proteins in the Trabecular Meshwork by Kasetti, Ramesh B, Phan, Tien N, Millar, J Cameron, Zode, Gulab S

“…Abnormal accumulation of extracellular matrix (ECM) in the trabecular meshwork (TM) is associated with decreased aqueous humor outflow facility and IOP…”
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Strain and Age Effects on Aqueous Humor Dynamics in the Mouse by Millar, J Cameron, Phan, Tien N, Pang, Iok-Hou, Clark, Abbot F

“…We evaluated differences in aqueous humor dynamics (AHD) among several mouse strains within younger and older age groups. Albino (A/J, BALB/cJ) and pigmented…”
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Prediction accuracy of genomic estimated breeding values for fruit traits in cultivated tomato (Solanum lycopersicum L.) by Yeon, Jeyun, Nguyen, Thuy Tien Phan, Kim, Minkyung, Sim, Sung-Chur

“…Genomic selection (GS) is an efficient breeding strategy to improve quantitative traits. It is necessary to calculate genomic estimated breeding values (GEBVs)…”
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A retrospective analysis to demonstrate achievable dosimetry for the left anterior descending artery in left-sided breast cancer patients treated with radiotherapy by Quirk, Sarah, Grendarova, Petra, Phan, Tien, Conroy, Leigh, Burke, Ben, Long, Karen, Thind, Kundan, Cao, Jeffrey, Craighead, Peter, Olivotto, Ivo A., Roumeliotis, Michael

“…•Dose to the LAD is reported for 1221 left-sided breast cancer patients.•Achievable LAD dose is reported in the context of modern motion management.•Cardiac…”
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Evaluation of physicochemical and hydromechanical properties of MSWI bottom ash for road construction by Le, Ngoc Hung, Razakamanantsoa, Andry, Nguyen, Mai-Lan, Phan, Van Tien, Dao, Phuc-Lam, Nguyen, Dang Hanh

“…•Physicochemical and geotechnical methodology are coupled to evaluate bottom ash.•Bottom ash characteristics are governed mainly by its SiO2 component.•Tested…”
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Arctigenin in combination with quercetin synergistically enhances the antiproliferative effect in prostate cancer cells by Wang, Piwen, Phan, Tien, Gordon, David, Chung, Seyung, Henning, Susanne M, Vadgama, Jaydutt V

“…SCOPE: We investigated whether a combination of two promising chemopreventive agents arctigenin (Arc) and quercetin (Q) increases the anticarcinogenic potency…”
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Governing energy consumption in Hadoop through CPU frequency scaling: An analysis by Ibrahim, Shadi, Phan, Tien-Dat, Carpen-Amarie, Alexandra, Chihoub, Houssem-Eddine, Moise, Diana, Antoniu, Gabriel

“…With increasingly inexpensive storage and growing processing power, the cloud has rapidly become the environment of choice to store and analyze data for a…”
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