Search Results - "Pham, Tuyetnhu"

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  1. 1

    An intergenic “safe haven” region in Aspergillus fumigatus by Pham, Tuyetnhu, Xie, Xiaofeng, Lin, Xiaorong

    Published in Medical mycology (Oxford) (10-11-2020)
    “…Abstract Aspergillus fumigatus is the most common opportunistic human fungal pathogen responsible for invasive aspergillosis. Gene manipulation is critical for…”
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    Journal Article
  2. 2

    Aspartyl peptidase May1 induces host inflammatory response by altering cell wall composition in the fungal pathogen Cryptococcus neoformans by Li, Yeqi, Chadwick, Benjamin, Pham, Tuyetnhu, Xie, Xiaofeng, Lin, Xiaorong

    Published in mBio (12-06-2024)
    “…causes cryptococcal meningoencephalitis, a disease that kills more than 180,000 people annually. Contributing to its success as a fungal pathogen is its cell…”
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    Journal Article
  3. 3

    The RAM signaling pathway links morphology, thermotolerance, and CO2 tolerance in the global fungal pathogen Cryptococcus neoformans by Chadwick, Benjamin J, Pham, Tuyetnhu, Xie, Xiaofeng, Ristow, Laura C, Krysan, Damian J, Lin, Xiaorong

    Published in eLife (23-11-2022)
    “…The environmental pathogen Cryptococcus neoformans claims over 180,000 lives each year. Survival of this basidiomycete at host CO 2 concentrations has only…”
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    Journal Article
  4. 4

    Immunoprotection against Cryptococcosis Offered by Znf2 Depends on Capsule and the Hyphal Morphology by Lin, Jianfeng, Pham, Tuyetnhu, Hipsher, Kenton, Glueck, Nathan, Fan, Yumeng, Lin, Xiaorong

    Published in mBio (22-02-2022)
    “…Systemic cryptococcosis is fatal without treatment. Globally, this disease kills 180,000 of the 225,000 infected people each year, even with the use of…”
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    Journal Article
  5. 5

    Antifungal Liposomes Directed by Dectin-2 Offer a Promising Therapeutic Option for Pulmonary Aspergillosis by Ambati, Suresh, Ellis, Emma C, Pham, Tuyetnhu, Lewis, Zachary A, Lin, Xiaorong, Meagher, Richard B

    Published in mBio (23-02-2021)
    “…Invasive fungal diseases cause millions of deaths each year. There are currently approximately 300,000 acute cases of aspergillosis, most of which result from…”
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    Journal Article
  6. 6

    Identification and Characterization of an Intergenic "Safe Haven" Region in Human Fungal Pathogen Cryptococcus gattii by Li, Yeqi, Pham, Tuyetnhu, Xie, Xiaofeng, Lin, Xiaorong

    Published in Journal of fungi (Basel) (11-02-2022)
    “…is a primary fungal pathogen, which causes pulmonary and brain infections in healthy as well as immunocompromised individuals. Genetic manipulations in this…”
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    Journal Article
  7. 7

    DC-SIGN targets amphotericin B-loaded liposomes to diverse pathogenic fungi by Ambati, Suresh, Pham, Tuyetnhu, Lewis, Zachary A, Lin, Xiaorong, Meagher, Richard B

    Published in Fungal biology and biotechnology (24-12-2021)
    “…Life-threatening invasive fungal infections are treated with antifungal drugs such as Amphotericin B (AmB) loaded liposomes. Our goal herein was to show that…”
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    Journal Article
  8. 8

    Raman Characterization of Fungal DHN and DOPA Melanin Biosynthesis Pathways by Strycker, Benjamin D., Han, Zehua, Bahari, Aysan, Pham, Tuyetnhu, Lin, Xiaorong, Shaw, Brian D., Sokolov, Alexei V., Scully, Marlan O.

    Published in Journal of fungi (Basel) (07-10-2021)
    “…Fungal melanins represent a resource for important breakthroughs in industry and medicine, but the characterization of their composition, synthesis, and…”
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    Journal Article
  9. 9

    Vaccination with a ZNF2 oe Strain of Cryptococcus Provides Long-Lasting Protection against Cryptococcosis and Is Effective in Immunocompromised Hosts by Pham, Tuyetnhu, Li, Yeqi, Watford, Wendy, Lin, Xiaorong

    Published in Infection and immunity (18-07-2023)
    “…Systemic cryptococcosis is fatal without treatment. Even with the current antifungal therapies, this disease kills 180,000 of 225,000 infected people annually…”
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    Journal Article
  10. 10

    Vaccination with a ZNF2oe Strain of Cryptococcus Provides Long-Lasting Protection against Cryptococcosis and Is Effective in Immunocompromised Hosts by Pham, Tuyetnhu, Li, Yeqi, Watford, Wendy, Lin, Xiaorong

    Published in Infection and immunity (18-07-2023)
    “…Systemic cryptococcosis is fatal without treatment. Even with the current antifungal therapies, this disease kills 180,000 of 225,000 infected people annually…”
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    Journal Article
  11. 11

    Small but mighty: targeted antifungal liposomes of a smaller size are superior in treating cryptococcal meningitis by Pham, Tuyetnhu, Zhang, Peter, Ambati, Suresh, Meagher, Richard B., Lin, Xiaorong

    Published in mBio (18-11-2024)
    “…Cryptococcal meningoencephalitis (CME) is deadly. CME is responsible for 19% of deaths in AIDS patients, and its global mortality is greater than 60%. The…”
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    Journal Article
  12. 12

    DectiSomes: Glycan Targeting of Liposomal Drugs Improves the Treatment of Disseminated Candidiasis by Ambati, Suresh, Pham, Tuyetnhu, Lewis, Zachary A, Lin, Xiaorong, Meagher, Richard B

    Published in Antimicrobial agents and chemotherapy (18-01-2022)
    “…Candida albicans causes life-threatening disseminated candidiasis. Individuals at greatest risk have weakened immune systems. An outer cell wall,…”
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    Journal Article
  13. 13

    All hands on Dec: Treating cryptococcosis with dectin decorated liposomes loaded with antifungals by Pham, Tuyetnhu, Shi, Ran, Ambati, Suresh, Meagher, Richard, Lin, Xiaorong

    Published in iScience (19-07-2024)
    “…Systemic cryptococcosis is often fatal even with the current antifungal therapy and there is no vaccine available. Induction therapy with amphotericin B (AmB)…”
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    Journal Article
  14. 14

    The RAM signaling pathway links morphology, thermotolerance, and CO.sub.2 tolerance in the global fungal pathogen Cryptococcus neoformans by Chadwick, Benjamin J, Pham, Tuyetnhu, Xie, Xiaofeng, Ristow, Laura C, Krysan, Damian J, Lin, Xiaorong

    Published in eLife (23-11-2022)
    “…The environmental pathogen Cryptococcus neoformans claims over 180,000 lives each year. Survival of this basidiomycete at host CO.sub.2 concentrations has only…”
    Get full text
    Journal Article
  15. 15

    The RAM signaling pathway links morphology, thermotolerance, and CO 2 tolerance in the global fungal pathogen Cryptococcus neoformans by Chadwick, Benjamin J, Pham, Tuyetnhu, Xie, Xiaofeng, Ristow, Laura C, Krysan, Damian J, Lin, Xiaorong

    Published in eLife (23-11-2022)
    “…The environmental pathogen claims over 180,000 lives each year. Survival of this basidiomycete at host CO concentrations has only recently been considered an…”
    Get full text
    Journal Article