Search Results - "Pham, Tuyetnhu"
-
1
An intergenic “safe haven” region in Aspergillus fumigatus
Published in Medical mycology (Oxford) (10-11-2020)“…Abstract Aspergillus fumigatus is the most common opportunistic human fungal pathogen responsible for invasive aspergillosis. Gene manipulation is critical for…”
Get full text
Journal Article -
2
Aspartyl peptidase May1 induces host inflammatory response by altering cell wall composition in the fungal pathogen Cryptococcus neoformans
Published in mBio (12-06-2024)“…causes cryptococcal meningoencephalitis, a disease that kills more than 180,000 people annually. Contributing to its success as a fungal pathogen is its cell…”
Get full text
Journal Article -
3
The RAM signaling pathway links morphology, thermotolerance, and CO2 tolerance in the global fungal pathogen Cryptococcus neoformans
Published in eLife (23-11-2022)“…The environmental pathogen Cryptococcus neoformans claims over 180,000 lives each year. Survival of this basidiomycete at host CO 2 concentrations has only…”
Get full text
Journal Article -
4
Immunoprotection against Cryptococcosis Offered by Znf2 Depends on Capsule and the Hyphal Morphology
Published in mBio (22-02-2022)“…Systemic cryptococcosis is fatal without treatment. Globally, this disease kills 180,000 of the 225,000 infected people each year, even with the use of…”
Get full text
Journal Article -
5
Antifungal Liposomes Directed by Dectin-2 Offer a Promising Therapeutic Option for Pulmonary Aspergillosis
Published in mBio (23-02-2021)“…Invasive fungal diseases cause millions of deaths each year. There are currently approximately 300,000 acute cases of aspergillosis, most of which result from…”
Get full text
Journal Article -
6
Identification and Characterization of an Intergenic "Safe Haven" Region in Human Fungal Pathogen Cryptococcus gattii
Published in Journal of fungi (Basel) (11-02-2022)“…is a primary fungal pathogen, which causes pulmonary and brain infections in healthy as well as immunocompromised individuals. Genetic manipulations in this…”
Get full text
Journal Article -
7
DC-SIGN targets amphotericin B-loaded liposomes to diverse pathogenic fungi
Published in Fungal biology and biotechnology (24-12-2021)“…Life-threatening invasive fungal infections are treated with antifungal drugs such as Amphotericin B (AmB) loaded liposomes. Our goal herein was to show that…”
Get full text
Journal Article -
8
Raman Characterization of Fungal DHN and DOPA Melanin Biosynthesis Pathways
Published in Journal of fungi (Basel) (07-10-2021)“…Fungal melanins represent a resource for important breakthroughs in industry and medicine, but the characterization of their composition, synthesis, and…”
Get full text
Journal Article -
9
Vaccination with a ZNF2 oe Strain of Cryptococcus Provides Long-Lasting Protection against Cryptococcosis and Is Effective in Immunocompromised Hosts
Published in Infection and immunity (18-07-2023)“…Systemic cryptococcosis is fatal without treatment. Even with the current antifungal therapies, this disease kills 180,000 of 225,000 infected people annually…”
Get full text
Journal Article -
10
Vaccination with a ZNF2oe Strain of Cryptococcus Provides Long-Lasting Protection against Cryptococcosis and Is Effective in Immunocompromised Hosts
Published in Infection and immunity (18-07-2023)“…Systemic cryptococcosis is fatal without treatment. Even with the current antifungal therapies, this disease kills 180,000 of 225,000 infected people annually…”
Get full text
Journal Article -
11
Small but mighty: targeted antifungal liposomes of a smaller size are superior in treating cryptococcal meningitis
Published in mBio (18-11-2024)“…Cryptococcal meningoencephalitis (CME) is deadly. CME is responsible for 19% of deaths in AIDS patients, and its global mortality is greater than 60%. The…”
Get full text
Journal Article -
12
DectiSomes: Glycan Targeting of Liposomal Drugs Improves the Treatment of Disseminated Candidiasis
Published in Antimicrobial agents and chemotherapy (18-01-2022)“…Candida albicans causes life-threatening disseminated candidiasis. Individuals at greatest risk have weakened immune systems. An outer cell wall,…”
Get full text
Journal Article -
13
All hands on Dec: Treating cryptococcosis with dectin decorated liposomes loaded with antifungals
Published in iScience (19-07-2024)“…Systemic cryptococcosis is often fatal even with the current antifungal therapy and there is no vaccine available. Induction therapy with amphotericin B (AmB)…”
Get full text
Journal Article -
14
The RAM signaling pathway links morphology, thermotolerance, and CO.sub.2 tolerance in the global fungal pathogen Cryptococcus neoformans
Published in eLife (23-11-2022)“…The environmental pathogen Cryptococcus neoformans claims over 180,000 lives each year. Survival of this basidiomycete at host CO.sub.2 concentrations has only…”
Get full text
Journal Article -
15
The RAM signaling pathway links morphology, thermotolerance, and CO 2 tolerance in the global fungal pathogen Cryptococcus neoformans
Published in eLife (23-11-2022)“…The environmental pathogen claims over 180,000 lives each year. Survival of this basidiomycete at host CO concentrations has only recently been considered an…”
Get full text
Journal Article