Search Results - "Pham, Khoa N"
-
1
Mapping the Binding Trajectory of a Suicide Inhibitor in Human Indoleamine 2,3-Dioxygenase 1
Published in Journal of the American Chemical Society (07-11-2018)“…Human indoleamine 2,3-dioxygenase 1 (hIDO1) is an important heme-containing enzyme that is a key drug target for cancer immunotherapy. Several hIDO1 inhibitors…”
Get full text
Journal Article -
2
Structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase 1
Published in Nature communications (22-11-2017)“…Human indoleamine 2,3-dioxygenase 1 (hIDO1) is an attractive cancer immunotherapeutic target owing to its role in promoting tumoral immune escape. However,…”
Get full text
Journal Article -
3
Diaryl hydroxylamines as pan or dual inhibitors of indoleamine 2,3-dioxygenase-1, indoleamine 2,3-dioxygenase-2 and tryptophan dioxygenase
Published in European journal of medicinal chemistry (15-01-2019)“…Tryptophan (Trp) catabolizing enzymes play an important and complex role in the development of cancer. Significant evidence implicates them in a range of…”
Get full text
Journal Article -
4
The effect of red wine in modifying the salivary pellicle and modulating dental erosion kinetics
Published in European journal of oral sciences (01-02-2021)“…This study investigated the potential of red wine in modulating dental erosion kinetics in the presence or absence of salivary pellicle. Polished human enamel…”
Get full text
Journal Article -
5
Structural Characterization of Human Histone H4.1 by Tandem Nonlinear and Linear Ion Mobility Spectrometry Complemented with Molecular Dynamics Simulations
Published in ACS omega (09-11-2021)“…Extracellular histone H4 is an attractive drug target owing to its roles in organ failure in sepsis and other diseases. To identify inhibitors using in silico…”
Get full text
Journal Article -
6
Structural Basis of Inhibitor Selectivity in Human Indoleamine 2,3-Dioxygenase 1 and Tryptophan Dioxygenase
Published in Journal of the American Chemical Society (27-11-2019)“…Indoleamine 2,3-dioxygenase 1 (hIDO1) and tryptophan dioxygenase (hTDO) are two of the only three heme-based dioxygenases in humans. They have recently been…”
Get full text
Journal Article -
7
Conformational Plasticity in Human Heme-Based Dioxygenases
Published in Journal of the American Chemical Society (03-02-2021)“…Human indoleamine 2,3-dioxygenase 1 (hIDO1) and human tryptophan dioxygenase (hTDO) are two important heme proteins that degrade the essential amino acid,…”
Get full text
Journal Article -
8
Correction to “Structural Heterogeneity of Human Histone H2A.1”
Published in The journal of physical chemistry. B (27-04-2023)Get full text
Journal Article -
9
Structural Heterogeneity of Human Histone H2A.1
Published in The journal of physical chemistry. B (20-05-2021)“…Histones are highly basic chromatin proteins that tightly package and order eukaryotic DNA into nucleosomes. While the atomic structure of the nucleosomes has…”
Get full text
Journal Article -
10
Structural Insights into Protein-Inhibitor Interactions in Human Tryptophan Dioxygenase
Published in Journal of medicinal chemistry (22-08-2024)“…Human tryptophan dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO) are two important targets in cancer immunotherapy. Extensive research has led to a…”
Get full text
Journal Article -
11
Surface modification for stability of nano-sized silica colloids
Published in Journal of colloid and interface science (01-11-2007)“…The surfaces of commercial 30-nm colloidal silica particles were modified by reacting with functional silanes. The high specific surface area and reactivity of…”
Get full text
Journal Article -
12
Nano-scale reservoir computing
Published in Nano communication networks (01-12-2013)“…This work describes preliminary steps towards nano-scale reservoir computing using quantum dots. Our research has focused on the development of an…”
Get full text
Journal Article -
13
RETRACTED: Surface modification for stability of nano-sized silica colloids
Published in Journal of colloid and interface science (01-11-2007)“…This article has been retracted at the request of the Handling Editor and Publisher, approved by EIC. Please see Elsevier Policy on Article Withdrawal (…”
Get full text
Journal Article -
14
Mapping the Binding Trajectory of a Suicide Inhibitor in Human Indoleamine 2,3 Dioxygenase 1
Published in Biophysical journal (15-02-2019)Get full text
Journal Article -
15
Identify the Binding Interface between Calsenilin and Presenilin 1 C-Terminal Fragment
Published in Biophysical journal (27-01-2015)Get full text
Journal Article -
16
Characterization of the Role of Individual EF-Hands in Dream in Modulating Conformational Dynamics, Oligomeric States, and Interaction with DNA
Published in Biophysical journal (16-02-2016)Get full text
Journal Article -
17
Spectroscopic Study Ca2+ Induced Changes in the Structure, Dynamics and Stability of Dream Protein and its Mechanism of DNA Interaction
Published in Biophysical journal (29-01-2013)Get full text
Journal Article -
18
-
19
To the editor
Published in The Journal of emergency medicine (01-07-2001)Get full text
Journal Article -
20