Search Results - "Pham, Khoa N"

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    Mapping the Binding Trajectory of a Suicide Inhibitor in Human Indoleamine 2,3-Dioxygenase 1 by Pham, Khoa N, Yeh, Syun-Ru

    Published in Journal of the American Chemical Society (07-11-2018)
    “…Human indoleamine 2,3-dioxygenase 1 (hIDO1) is an important heme-containing enzyme that is a key drug target for cancer immunotherapy. Several hIDO1 inhibitors…”
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    Structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase 1 by Lewis-Ballester, Ariel, Pham, Khoa N., Batabyal, Dipanwita, Karkashon, Shay, Bonanno, Jeffrey B., Poulos, Thomas L., Yeh, Syun-Ru

    Published in Nature communications (22-11-2017)
    “…Human indoleamine 2,3-dioxygenase 1 (hIDO1) is an attractive cancer immunotherapeutic target owing to its role in promoting tumoral immune escape. However,…”
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    The effect of red wine in modifying the salivary pellicle and modulating dental erosion kinetics by Carvalho, Thiago S., Pham, Khoa N., Niemeyer, Samira H., Baumann, Tommy

    Published in European journal of oral sciences (01-02-2021)
    “…This study investigated the potential of red wine in modulating dental erosion kinetics in the presence or absence of salivary pellicle. Polished human enamel…”
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    Structural Characterization of Human Histone H4.1 by Tandem Nonlinear and Linear Ion Mobility Spectrometry Complemented with Molecular Dynamics Simulations by Pham, Khoa N, Fernandez-Lima, Francisco

    Published in ACS omega (09-11-2021)
    “…Extracellular histone H4 is an attractive drug target owing to its roles in organ failure in sepsis and other diseases. To identify inhibitors using in silico…”
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    Structural Basis of Inhibitor Selectivity in Human Indoleamine 2,3-Dioxygenase 1 and Tryptophan Dioxygenase by Pham, Khoa N, Lewis-Ballester, Ariel, Yeh, Syun-Ru

    Published in Journal of the American Chemical Society (27-11-2019)
    “…Indoleamine 2,3-dioxygenase 1 (hIDO1) and tryptophan dioxygenase (hTDO) are two of the only three heme-based dioxygenases in humans. They have recently been…”
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    Conformational Plasticity in Human Heme-Based Dioxygenases by Pham, Khoa N, Lewis-Ballester, Ariel, Yeh, Syun-Ru

    Published in Journal of the American Chemical Society (03-02-2021)
    “…Human indoleamine 2,3-dioxygenase 1 (hIDO1) and human tryptophan dioxygenase (hTDO) are two important heme proteins that degrade the essential amino acid,…”
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    Structural Heterogeneity of Human Histone H2A.1 by Pham, Khoa N, Mamun, Yasir, Fernandez-Lima, Francisco

    Published in The journal of physical chemistry. B (20-05-2021)
    “…Histones are highly basic chromatin proteins that tightly package and order eukaryotic DNA into nucleosomes. While the atomic structure of the nucleosomes has…”
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    Structural Insights into Protein-Inhibitor Interactions in Human Tryptophan Dioxygenase by Geeraerts, Zachary, Ishigami, Izumi, Lewis-Ballester, Ariel, Pham, Khoa N., Kozlova, Arina, Mathieu, Caroline, Frédérick, Raphaël, Yeh, Syun-Ru

    Published in Journal of medicinal chemistry (22-08-2024)
    “…Human tryptophan dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO) are two important targets in cancer immunotherapy. Extensive research has led to a…”
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    Surface modification for stability of nano-sized silica colloids by PHAM, Khoa N, FULLSTON, Damian, SAGOE-CRENTSIL, Kwesi

    Published in Journal of colloid and interface science (01-11-2007)
    “…The surfaces of commercial 30-nm colloidal silica particles were modified by reacting with functional silanes. The high specific surface area and reactivity of…”
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    Nano-scale reservoir computing by Obst, Oliver, Trinchi, Adrian, Hardin, Simon G., Chadwick, Matthew, Cole, Ivan, Muster, Tim H., Hoschke, Nigel, Ostry, Diet, Price, Don, Pham, Khoa N., Wark, Tim

    Published in Nano communication networks (01-12-2013)
    “…This work describes preliminary steps towards nano-scale reservoir computing using quantum dots. Our research has focused on the development of an…”
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    RETRACTED: Surface modification for stability of nano-sized silica colloids by Pham, Khoa N., Fullston, Damian, Sagoe-Crentsil, Kwesi

    Published in Journal of colloid and interface science (01-11-2007)
    “…This article has been retracted at the request of the Handling Editor and Publisher, approved by EIC. Please see Elsevier Policy on Article Withdrawal (…”
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