Search Results - "Pham, Anna C"
-
1
Characterization of Solubilizing Nanoaggregates Present in Different Versions of Simulated Intestinal Fluid
Published in The journal of physical chemistry. B (07-12-2017)“…The absorption of hydrophobic drugs and nutrients from the intestine is principally determined by the amount that can be dissolved by the endogenous fluids…”
Get full text
Journal Article -
2
Formation of Self-Assembled Mesophases During Lipid Digestion
Published in Frontiers in cell and developmental biology (11-06-2021)“…Lipids play an important role in regulating bodily functions and providing a source of energy. Lipids enter the body primarily in the form of triglycerides in…”
Get full text
Journal Article -
3
Infant formula as a solid lipid dose form for enhancement of the oral bioavailability of cannabidiol for paediatric patients
Published in International journal of pharmaceutics (20-07-2024)“…[Display omitted] Cannabinoids can save paediatric patients from harmful psychological conditions caused by epilepsy. However, the limited aqueous solubility…”
Get full text
Journal Article -
4
The impact of digestion is essential to the understanding of milk as a drug delivery system for poorly water soluble drugs
Published in Journal of controlled release (28-12-2018)“…Milk has previously been considered as a potential lipid-based drug delivery system for poorly water soluble drugs but it has never gained significant…”
Get full text
Journal Article -
5
A new lipid excipient, phosphorylated tocopherol mixture, TPM enhances the solubilisation and oral bioavailability of poorly water soluble CoQ10 in a lipid formulation
Published in Journal of controlled release (28-12-2017)“…Phosphorylated tocopherols are a new class of lipid excipients that have demonstrated potential in pharmaceutical applications. Their ability to solubilise…”
Get full text
Journal Article -
6
Towards mesoporous silica as a pharmaceutical treatment for obesity - impact on lipid digestion and absorption
Published in European journal of pharmaceutics and biopharmaceutics (01-04-2022)“…[Display omitted] Mesoporous silica particles (MSPs) are emerging as an interesting option to reduce calorific uptake as a treatment for obesity and other…”
Get full text
Journal Article -
7
A Nonionic Polyethylene Oxide (PEO) Surfactant Model: Experimental and Molecular Dynamics Studies of Kolliphor EL
Published in Journal of pharmaceutical sciences (01-01-2019)“…Polyethoxylated, nonionic surfactants are important constituents of many drug formulations, including lipid-based formulations. In an effort to better…”
Get more information
Journal Article -
8
In Vivo Formation of Cubic Phase in Situ after Oral Administration of Cubic Phase Precursor Formulation Provides Long Duration Gastric Retention and Absorption for Poorly Water-Soluble Drugs
Published in Molecular pharmaceutics (04-01-2016)“…Lipid-based liquid crystalline systems based on the combination of digestible and nondigestible lipids have been proposed as potential sustained release…”
Get full text
Journal Article -
9
Sustained absorption of delamanid from lipid-based formulations as a path to reduced frequency of administration
Published in Drug delivery and translational research (01-06-2021)“…Delamanid is a poorly water-soluble drug currently being used for the treatment of tuberculosis. The high frequency of dosing leads to poor adherence for…”
Get full text
Journal Article -
10
Correlating Digestion-Driven Self-Assembly in Milk and Infant Formulas with Changes in Lipid Composition
Published in ACS applied bio materials (18-05-2020)“…Lipids in mammalian milks such as bovine milk and human breast milk have been shown to self-assemble into various liquid crystalline materials during…”
Get full text
Journal Article -
11
Examining the gastrointestinal transit of lipid-based liquid crystalline systems using whole-animal imaging
Published in Drug delivery and translational research (01-12-2015)“…Lipid-based liquid crystalline (LC) systems have the potential to sustain the oral absorption of poorly water-soluble drugs in vivo, facilitating slow drug…”
Get full text
Journal Article -
12
Dissolution of pain-relief drugs: Does beverage choice matter?
Published in Journal of drug delivery science and technology (01-01-2024)Get full text
Journal Article -
13
A new lipid excipient, phosphorylated tocopherol mixture, TPM enhances the solubilisation and oral bioavailability of poorly water soluble CoQ 10 in a lipid formulation
Published in Journal of controlled release (28-12-2017)“…Phosphorylated tocopherols are a new class of lipid excipients that have demonstrated potential in pharmaceutical applications. Their ability to solubilise…”
Get full text
Journal Article