Search Results - "Pfosser, Achim"

An angiogenic role for the human peptide antibiotic LL-37/hCAP-18 by Koczulla, Rembert, von Degenfeld, Georges, Kupatt, Christian, Krötz, Florian, Zahler, Stefan, Gloe, Torsten, Issbrücker, Katja, Unterberger, Pia, Zaiou, Mohamed, Lebherz, Corinna, Karl, Alexander, Raake, Philip, Pfosser, Achim, Boekstegers, Peter, Welsch, Ulrich, Hiemstra, Pieter S, Vogelmeier, Claus, Gallo, Richard L, Clauss, Matthias, Bals, Robert

“…Antimicrobial peptides are effector molecules of the innate immune system and contribute to host defense and regulation of inflammation. The human cathelicidin…”
Get full text

An angiogenic role for the human peptide antibiotic LL-37/hCAP-18 by Koczulla, Rembert, von Degenfeld, Georges, Kupatt, Christian, Krötz, Florian, Zahler, Stefan, Gloe, Torsten, Issbrücker, Katja, Unterberger, Pia, Zaiou, Mohamed, Lebherz, Corinna, Karl, Alexander, Raake, Philip, Pfosser, Achim, Boekstegers, Peter, Welsch, Ulrich, Hiemstra, Pieter S., Vogelmeier, Claus, Gallo, Richard L., Clauss, Matthias, Bals, Robert

“…Antimicrobial peptides are effector molecules of the innate immune system and contribute to host defense and regulation of inflammation. The human cathelicidin…”
Get full text

Cotransfection of Vascular Endothelial Growth Factor-A and Platelet-Derived Growth Factor-B Via Recombinant Adeno-Associated Virus Resolves Chronic Ischemic Malperfusion by Kupatt, Christian, MD, Hinkel, Rabea, DVM, Pfosser, Achim, MD, El-Aouni, Chiraz, PhD, Wuchrer, Alexander, MD, Fritz, Andrea, MD, Globisch, Franziska, MD, Thormann, Michael, DVM, Horstkotte, Jan, MD, Lebherz, Corinna, MD, Thein, Eckart, DVM, Banfi, Andrea, PhD, Boekstegers, Peter, MD

“…Objectives We set out to investigate the ability of cardiotropic adeno-associated viral vector (AAV2.9 = recombinant adeno-associated virus [rAAV]) to induce…”
Get full text

Role of target antigen in bispecific‐antibody‐mediated killing of human glioblastoma cells: A pre‐clinical study by Pfosser, Achim, Brandl, Martina, Salih, Helmut, Grosse‐Hovest, Ludger, Jung, Gundram

“…Bispecific antibodies (bsAbs) directed to tumor‐associated antigens and to receptors mediating T‐cell activation, such as the TCR/CD3 complex and the…”
Get full text

Cotransfection of Vascular Endothelial Growth Factor-A and Platelet-Derived Growth Factor-B Via Recombinant Adeno-Associated Virus Resolves Chronic Ischemic Malperfusion: Role of Vessel Maturation by KUPATT, Christian, HINKEL, Rabea, THEIN, Eckart, BANFI, Andrea, BOEKSTEGERS, Peter, PFOSSER, Achim, EL-AOUNI, Chiraz, WUCHRER, Alexander, FRITZ, Andrea, GLOBISCH, Franziska, THORMANN, Michael, HORSTKOTTE, Jan, LEBHERZ, Corinna

“…We set out to investigate the ability of cardiotropic adeno-associated viral vector (AAV2.9 = recombinant adeno-associated virus [rAAV]) to induce prolonged…”
Get full text

SDF‐1 fused to a fractalkine stalk and a GPI anchor enables functional neovascularization by Stachel, Georg, Trenkwalder, Teresa, Götz, Franziska, El Aouni, Chiraz, Muenchmeier, Niklas, Pfosser, Achim, Nussbaum, Claudia, Sperandio, Markus, Hatzopoulos, Antonis K., Hinkel, Rabea, Nelson, Peter J., Kupatt, Christian

“…ABSTRACT The facilitated recruitment of vascular progenitor cells (VPCs) to ischemic areas might be a therapeutic target for neovascularization and repair…”
Get full text

NF κB Activation in Embryonic Endothelial Progenitor Cells Enhances Neovascularization via PSGL‐1 Mediated Recruitment: Novel Role for LL37 by Pfosser, Achim, El‐Aouni, Chiraz, Pfisterer, Iris, Dietz, Melanie, Globisch, Franziska, Stachel, Georg, Trenkwalder, Teresa, Pinkenburg, Olaf, Horstkotte, Jan, Hinkel, Rabea, Sperandio, Markus, Hatzopoulos, Antonis K., Boekstegers, Peter, Bals, Robert, Kupatt, Christian

“…Embryonal endothelial progenitor cells (eEPCs) are capable of inducing therapeutic angiogenesis in a chronic hind limb model. However, the proportion of eEPCs…”
Get full text

Embryonic endothelial progenitor cells expressing a broad range of proangiogenic and remodeling factors enhance vascularization and tissue recovery in acute and chronic ischemia by Kupatt, Christian, Horstkotte, Jan, Vlastos, Georgios A, Pfosser, Achim, Lebherz, Corinna, Semisch, Matthias, Thalgott, Mark, Bůttner, Kerstin, Browarzyk, Christian, Mages, Jörg, Hoffmann, Reinhard, Deten, Alexander, Lamparter, Mathias, Můller, Fabian, Beck, Heike, Bůning, Hildegard, Boekstegers, Peter, Hatzopoulos, Antonis K

“…ABSTRACTClonal embryonic endothelial progenitor cells (eEPCs) isolated from embryonic day 7.5 mice home specifically to hypoxic areas in mouse tumor metastases…”
Get full text

Abstract 5603: LL-37 Improves Adhesion and Therapeutic Effects of Embryonic EPCs in Chronic Ischemia (Rabbit Model) by Pfosser, Achim, Hinkel, Rabea, Stachel, Georg, Trenkwalder, Teresa, Hatzopoulos, Antonis, Bals, Robert, Kupatt, Christian

“…Abstract only Therapeutic neovascularization can be achieved by vascular growth factors or by mobilisation or exogenous application of endothelial progenitor…”
Get full text

Liposomal Hsp90 cDNA induces neovascularization via nitric oxide in chronic ischemia by Pfosser, Achim, Thalgott, Mark, Büttner, Kerstin, Brouet, Agnès, Feron, Olivier, Boekstegers, Peter, Kupatt, Christian

“…Induction of angiogenesis has been reported subsequent to eNOS overexpression or activation, the latter involving Hsp90 as a chaperone protein. Here, we…”
Get full text

Adult presentation of combined unilateral atresia of the right proximal pulmonary artery and left patent ductus arteriosus: Case report and embryological considerations by Deutsch, Marcus-André, Thieme, Sven F, Hinterseer, Martin, Johnson, Thorsten R.C, Pfosser, Achim, Reichart, Bruno, Nikolaou, Konstantin, Behr, Jürgen

“…Abstract We report on a rare case of combined unilateral atresia of the proximal right pulmonary artery (PA) and left patent ductus arteriosus (PDA). A…”
Get full text

Abstract 5590: Therapeutic Neovascularization by AAV 2/9-based Gene Transfer of hVEGF-A and hPDGF-b in Chronic Ischemia (Pig and Rabbit Model) by Pfosser, Achim, Hinkel, Rabea, Thormann, Michael, Lebherz, Corinna, Wuchrer, Alexander, Globisch, Franziska, El-Aouni, Chiraz, Banfi, Andrea, Boekstegers, Peter, Kupatt, Christian

“…Abstract only In patients suffering from ischemic cardiomyopathy or peripheral artery disease, lacking interventional or surgical treatment options, induction…”
Get full text

Abstract 3955: Chemokines Fused to a Fractalkine Backbone and a GPI-Anchor Attract Embryonic Endothelial Progenitor Cells to the Site of Ischemia by El-Aouni, Chiraz, Globisch, Franziska, Pfosser, Achim, Stachel, Georg, Hinkel, Rabea, Boekstegers, Peter, Nelson, Peter, Kupatt, Christian

“…Abstract only Recruitment of endothelial progenitor cells to the sites of ischemia is a prerequisite for efficient therapeutic neovascularization via…”
Get full text

Abstract 247: Therapeutic Neovascularization by AAV2/9 Based Gene Transfer of hVEGF-A and hPDGF in Chronic Ischemia (rabbit model) by Pfosser, Achim, El-Aouni, Chiraz, Globisch, Franziska, Dinges, Claudia, Fritz, Andrea, Sultana, Shahana, Hinkel, Rabea, Lebherz, Corinna, Banfi, Andrea, Boekstegers, Peter, Kupatt, Christian

“…Abstract only Therapeutic neovascularization by several growth factors is a concept well established in multiple animal models, albeit lacking clearcut…”
Get full text

Recombinant adeno-associated virus-based gene transfer of cathelicidin induces therapeutic neovascularization preferentially via potent collateral growth by Pinkenburg, Olaf, Pfosser, Achim, Hinkel, Rabea, Böttcher, Martina, Dinges, Claudia, Lebherz, Corinna, Sultana, Shahana, Enssle, Jörg, El-Aouni, Chiraz, Büning, Hildegard, Boekstegers, Peter, Bals, Robert, Kupatt, Christian

“…Therapeutic neovascularization is a concept well validated in animal models, however, without clear-cut success in clinical studies. To achieve prolonged…”
Get more information

NF kappaB activation in embryonic endothelial progenitor cells enhances neovascularization via PSGL-1 mediated recruitment: novel role for LL37 by Pfosser, Achim, El-Aouni, Chiraz, Pfisterer, Iris, Dietz, Melanie, Globisch, Franziska, Stachel, Georg, Trenkwalder, Teresa, Pinkenburg, Olaf, Horstkotte, Jan, Hinkel, Rabea, Sperandio, Markus, Hatzopoulos, Antonis K, Boekstegers, Peter, Bals, Robert, Kupatt, Christian

“…Embryonal endothelial progenitor cells (eEPCs) are capable of inducing therapeutic angiogenesis in a chronic hind limb model. However, the proportion of eEPCs…”
Get full text

Therapeutic angiogenesis/arteriogenesis in the chronic ischemic rabbit hindlimb: effect of venous basic fibroblast growth factor retroinfusion by Lebherz, Corinna, von Degenfeld, Georges, Karl, Alexander, Pfosser, Achim, Raake, Philip, Pachmayr, Florian, Scholz, Dimitri, Kupatt, Christian, Boekstegers, Peter

“…Therapeutic induction of angiogenesis has been shown in experimental hindlimb ischemia. An alternative to targeting the ischemic hindlimb tissue via the…”
Get more information

Tumor immunotherapy with bispecific antibodies: from bench- to bedside by Jung, Gundram, Große-Hovest, Ludger, Brandl, Martina, Pfosser, Achim, Wilmanns, Wofgang

Get full text

Liposomal Hsp90 cDNA induces neovascularization via nitric oxide in chronic ischemia by PFOSSER, Achim, THALGOH, Mark, BÜTTNER, Kerstin, BROUET, Agnès, FERON, Olivier, BOEKSTEGERS, Peter, KUPATT, Christian

Get full text

Adult presentation of combined unilateral atresia of the right proximal pulmonary artery and left patent ductus arteriosus: case report and embryological considerations by Deutsch, Marcus-André, Thieme, Sven F, Hinterseer, Martin, Johnson, Thorsten R C, Pfosser, Achim, Reichart, Bruno, Nikolaou, Konstantin, Behr, Jürgen

“…We report on a rare case of combined unilateral atresia of the proximal right pulmonary artery (PA) and left patent ductus arteriosus (PDA). A 46 year-old…”
Get full text