Search Results - "Pflugfelder, Gert O."
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The Tbx6 Transcription Factor Dorsocross Mediates Dpp Signaling to Regulate Drosophila Thorax Closure
Published in International journal of molecular sciences (20-04-2022)“…Movement and fusion of separate cell populations are critical for several developmental processes, such as neural tube closure in vertebrates or embryonic…”
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2
Putative Breast Cancer Driver Mutations in TBX3 Cause Impaired Transcriptional Repression
Published in Frontiers in oncology (29-10-2015)“…The closely related T-box transcription factors TBX2 and TBX3 are frequently overexpressed in melanoma and various types of human cancers, in particular,…”
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3
The Transcription Factors TBX2 and TBX3 Interact with Human Papillomavirus 16 (HPV16) L2 and Repress the Long Control Region of HPVs
Published in Journal of Virology (01-04-2013)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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4
Optomotor-blind negatively regulates Drosophila eye development by blocking Jak/STAT signaling
Published in PloS one (17-03-2015)“…Organ formation requires a delicate balance of positive and negative regulators. In Drosophila eye development, wingless (wg) is expressed at the lateral…”
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5
The Dorsocross T-box transcription factors promote tissue morphogenesis in the Drosophila wing imaginal disc
Published in Development (Cambridge) (01-08-2012)“…The Drosophila wing imaginal disc is subdivided into notum, hinge and blade territories during the third larval instar by formation of several deep apical…”
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6
Fold formation at the compartment boundary of Drosophila wing requires Yki signaling to suppress JNK dependent apoptosis
Published in Scientific reports (29-11-2016)“…Compartment boundaries prevent cell populations of different lineage from intermingling. In many cases, compartment boundaries are associated with…”
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7
Dpp signaling inhibits proliferation in the Drosophila wing by Omb-dependent regional control of bantam
Published in Development (Cambridge) (15-07-2013)“…The control of organ growth is a fundamental aspect of animal development but remains poorly understood. The morphogen Dpp has long been considered as a…”
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8
A Fluorescent Core−Shell Dendritic Macromolecule Specifically Stains The Extracellular Matrix
Published in Journal of the American Chemical Society (25-06-2008)“…The extracellular cell matrix (ECM) surrounds cells and plays important roles in many aspects of cellular fate, including cell migration, stem cell…”
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9
Glial and neuronal expression of polyglutamine proteins induce behavioral changes and aggregate formation in Drosophila
Published in Glia (01-01-2005)“…Patients with polyglutamine expansion diseases, like Huntington's disease or several spinocerebellar ataxias, first present with neurological symptoms that can…”
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10
Fluorescent Core/Shell Nanoparticles for Specific Cell-Nucleus Staining
Published in Small (Weinheim an der Bergstrasse, Germany) (01-07-2008)“…Water‐soluble fluorescent core/shell nanoparticles containing multiple ‐COOH groups are synthesized via atom‐transfer radical polymerization by applying…”
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The orthologous Tbx transcription factors Omb and TBX2 induce epithelial cell migration and extrusion in vivo without involvement of matrix metalloproteinases
Published in Oncotarget (15-12-2014)“…The transcription factors TBX2 and TBX3 are overexpressed in various human cancers. Here, we investigated the effect of overexpressing the orthologous Tbx…”
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12
Spatial discontinuity of optomotor-blind expression in the Drosophila wing imaginal disc disrupts epithelial architecture and promotes cell sorting
Published in BMC developmental biology (23-02-2010)“…Decapentaplegic (Dpp) is one of the best characterized morphogens, required for dorso-ventral patterning of the Drosophila embryo and for anterior-posterior…”
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13
Optomotor-blind expression in glial cells is required for correct axonal projection across the Drosophila inner optic chiasm
Published in Developmental biology (01-03-2008)“…In the Drosophila adult visual system, photoreceptor axons and their connecting interneurons are tied into a retinotopic pattern throughout the consecutive…”
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14
Optomotor-blind in the Development of the Drosophila HS and VS Lobula Plate Tangential Cells
Published in Journal of neurogenetics (01-12-2014)“…Abstract The horizontal system and vertical system cells of the dipteran optic lobes are well understood regarding their physiology and role in visually guided…”
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15
Functional identity of hypothalamic melanocortin neurons depends on Tbx3
Published in Nature metabolism (01-02-2019)“…Heterogeneous populations of hypothalamic neurons orchestrate energy balance via the release of specific signatures of neuropeptides. However, how specific…”
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16
Enhancer trap infidelity in Drosophila optomotor-blind
Published in Fly (Austin, Tex.) (01-04-2013)“…Reporter gene activity in enhancer trap lines is often implicitly assumed to mirror quite faithfully the endogenous expression of the "trapped" gene, even…”
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17
Invertebrate Synapsins: A Single Gene Codes for Several Isoforms in Drosophila
Published in The Journal of neuroscience (15-05-1996)“…Vertebrate synapsins constitute a family of synaptic proteins that participate in the regulation of neurotransmitter release. Information on the presence of…”
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18
Null mutations in Drosophila Optomotor-blind affect T-domain residues conserved in all Tbx proteins
Published in Molecular genetics and genomics : MGG (01-02-2010)“…The T-box transcription factors TBX2 and TBX3 are overexpressed in many human cancers raising the need for a thorough understanding of the cellular function of…”
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19
Control of the gene optomotor-blind in Drosophila wing development by decapentaplegic and wingless
Published in Science (American Association for the Advancement of Science) (15-03-1996)“…Diffusible factors of several protein families control appendage outgrowth and patterning in both insects and vertebrates. In Drosophila wing development, the…”
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20
Defective Pigment Granule Biogenesis and Aberrant Behavior Caused by Mutations in the Drosophila AP-3β Adaptin Gene ruby
Published in Genetics (Austin) (01-05-2000)“…Lysosomal protein trafficking is a fundamental process conserved from yeast to humans. This conservation extends to lysosome-like organelles such as mammalian…”
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